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About

I graduated in Applied Physics (Optics and Lasers) at the University of Minho (1996), obtained the MSc in Optoelectronics and Lasers at the Physics Department of the University of Porto (2000); in 2006 I concluded a PhD program at Porto University in collaboration with the Department of Physics and Optical Sciences at the University of North Carolina at Charlotte, NC, USA, with work in luminescence based optical fibre systems for biochemical sensing applications using quantum dots. Since 1997 I have been involved in several research and technology transfer projects related to optical fibre sensing technology, developing new sensing configurations and interrogation techniques for optical sensors. I am, since 2007 a Senior researcher at INESC TEC reponsible for the Biochemical Sensors team, where we explore the potential of optical fibre and integrated optics technologies in environmental and medical applications framed by several R&D projects. I have more than 200 publications in the fields of sensors in national and international conferences and peer reviewed journals, I am author of 3 book chapters and also hold one patent. I am a member of SPIE and SPOF.

Interest
Topics
Details

Details

  • Nationality

    Portugal
  • Centre

    Applied Photonics
  • Contacts

    +351220402301
    pedro.jorge@inesctec.pt
029
Publications

2021

Biosensors for Biogenic Amines: A Review

Authors
Vasconcelos, H; Coelho, LCC; Matias, A; Saraiva, C; Jorge, PAS; de Almeida, JMMM;

Publication
Biosensors

Abstract
Biogenic amines (BAs) are well-known biomolecules, mostly for their toxic and carcinogenic effects. Commonly, they are used as an indicator of quality preservation in food and beverages since their presence in higher concentrations is associated with poor quality. With respect to BA’s metabolic pathways, time plays a crucial factor in their formation. They are mainly formed by microbial decarboxylation of amino acids, which is closely related to food deterioration, therefore, making them unfit for human consumption. Pathogenic microorganisms grow in food without any noticeable change in odor, appearance, or taste, thus, they can reach toxic concentrations. The present review provides an overview of the most recent literature on BAs with special emphasis on food matrixes, including a description of the typical BA assay formats, along with its general structure, according to the biorecognition elements used (enzymes, nucleic acids, whole cells, and antibodies). The extensive and significant amount of research that has been done to the investigation of biorecognition elements, transducers, and their integration in biosensors, over the years has been reviewed.

2021

Development of a Long Period Fiber Grating Interrogation System Using A Multimode Laser Diode

Authors
Silva, LH; Santos, P; Coelho, LCC; Jorge, P; Baptista, JM;

Publication
Sensors

Abstract
Optical fiber gratings have long shown their sensing capabilities. One of the main challenges, however, is the interrogation method applied, since typical systems tend to use broadband light sources with optical spectrum analyzers, laser scanning units or CCD (Charged Coupled Device) spectrometers. The following paper presents the development of an interrogation system, which explores the temperature response of a multimode laser diode, in order to interrogate long period fiber gratings. By performing a spectral sweep along one of its rejection bands, a discrete attenuation spectrum is created. Through a curve fitting technique, the original spectrum is restored. The built unit, while presenting a substantially reduced cost compared with typical interrogation systems, is capable of interrogating along a 10 nm window with measurement errors reaching minimum values as low as 0.4 nm, regarding the grating central wavelength, and 0.4 dB for its attenuation. Given its low cost and reduced dimensions, the developed system shows potential for slow-changing field applications.

2021

Effect of low-doses of gamma radiation on electric arc-induced long period fiber gratings

Authors
Mesonero Santos, P; Fernandez Medina, A; Coelho, LCC; Viveiros, D; Jorge, PA; Belenguer, T; Heredero, RL;

Publication
Sensors

Abstract
This work presents an experimental study on the effects of gamma radiation on Long Period Fiber Gratings (LPFGs) in a low-dose test campaign to evaluate their eventual degradation. The study was carried out with standard single-mode fibers where the grating was inscribed using the Electric-Arc Discharge (EAD) technique. Before the gamma campaign, a detailed optical characterization was performed with repeatability tests to verify the accuracy of the setup and the associated error sources. The gamma-induced changes up to a dose of 200 krad and the recovery after radiation were monitored with the Dip Wavelength Shift (DWS). The results show that the gamma sensitivity for a total dose of 200 krad is 11 pm/krad and a total DWS of 2.3 nm has been observed with no linear dependence. Post-radiation study shows that recovery from radiation-induced wavelength shift is nearly complete in about 4000 h. Experimental results show that the changes suffered under gamma irradiation of these LPFGs are temporary making them a good choice as sensors in space applications. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

2021

Detection of biogenic amines in several foods with different sample treatments: An overview

Authors
Vasconcelos, H; de Almeida, JMMM; Matias, A; Saraiva, C; Jorge, PAS; Coelho, LCC;

Publication
Trends in Food Science & Technology

Abstract

2020

iLoF: An intelligent Lab on Fiber Approach for Human Cancer Single-Cell Type Identification

Authors
Paiva, JS; Jorge, PAS; Ribeiro, RSR; Balmana, M; Campos, D; Mereiter, S; Jin, CS; Karlsson, NG; Sampaio, P; Reis, CA; Cunha, JPS;

Publication
Scientific reports

Abstract
With the advent of personalized medicine, there is a movement to develop "smaller" and "smarter" microdevices that are able to distinguish similar cancer subtypes. Tumor cells display major differences when compared to their natural counterparts, due to alterations in fundamental cellular processes such as glycosylation. Glycans are involved in tumor cell biology and they have been considered to be suitable cancer biomarkers. Thus, more selective cancer screening assays can be developed through the detection of specific altered glycans on the surface of circulating cancer cells. Currently, this is only possible through time-consuming assays. In this work, we propose the "intelligent" Lab on Fiber (iLoF) device, that has a high-resolution, and which is a fast and portable method for tumor single-cell type identification and isolation. We apply an Artificial Intelligence approach to the back-scattered signal arising from a trapped cell by a micro-lensed optical fiber. As a proof of concept, we show that iLoF is able to discriminate two human cancer cell models sharing the same genetic background but displaying a different surface glycosylation profile with an accuracy above 90% and a speed rate of 2.3 seconds. We envision the incorporation of the iLoF in an easy-to-operate microchip for cancer identification, which would allow further biological characterization of the captured circulating live cells.

Supervised
thesis

2020

Fiber Laser Plasma Spectroscopy for Real-Time

Author
Miguel Fernandes Soares Ferreira

Institution
UP-FCUP

2020

Laser Induced Breakdown Spectroscopy (LIBS) as an analytical tool for geological samples

Author
Diana Faria Capela

Institution
UP-FCUP

2020

Fast prototyping of advanced sensing devices using three-dimensional direct writing with femtosecond laser

Author
Vítor Alexandre Oliveira Amorim

Institution
UP-FCUP

2020

Development of differential optrodes for highly sensitive and reliable chemical sensing

Author
João Pedro Sampaio Mendes

Institution
UP-FCUP

2020

Optimization of LaserInduced Breakdown Spectroscopy (LIBS) for application in the cork industry

Author
Hugo Azevedo Veloso

Institution
UP-FCUP