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Sobre
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Sobre

Licenciei-me em Física Aplicada (Otíca e Lasers) pela Universidade do Minho (1996), tendo obtido o Mestrado em Lasers e Optoelectrónica no Departamento de Física da Faculdade de Ciências da Universidade do Porto (2000). Em 2006 conclui o Doutoramento em Física pela Universidade do Porto, em colaboração com o Department of Physics and Optical Sciences da University of North Carolina at Charlotte, EUA, com trabalho em sensores em fibra ótica baseados em luminescência de Quantum dots, para medição de parâmetros bioquímicos. Desde 1997 tenho estado envolvido em diversos projectos de investigação e desenvolvimento e transferência de tecnologia relacionados com tecnologia de sensores em fibra ótica, desenvolvendo novas configurações e técnicas de interrogação para sensores óticos. Presentemente e desde 2007 sou investigador Sénior do INESC TEC responsável pela equipa de sensores bioquímicos, onde exploramos o potencial das tecnologias de fibra ótica e ótica integrada em aplicações médicas e de monitorização ambiental, enquadrados em diferentes projectos de investigação e dsenvolvimento.  Sou autor de mais de 200 publicações ná àrea dos sensores, em conferências nacionais e internacionais e em jornais da especialidade, com revisão por pares. Sou autor de 3 capitulos de livro e de uma patente. Sou membro da SPIE e da SPOF.

Tópicos
de interesse
Detalhes

Detalhes

028
Publicações

2020

iLoF: An intelligent Lab on Fiber Approach for Human Cancer Single-Cell Type Identification

Autores
Paiva, JS; Jorge, PAS; Ribeiro, RSR; Balmaña, M; Campos, D; Mereiter, S; Jin, C; Karlsson, NG; Sampaio, P; Reis, CA; Cunha, JPS;

Publicação
Scientific reports

Abstract
With the advent of personalized medicine, there is a movement to develop "smaller" and "smarter" microdevices that are able to distinguish similar cancer subtypes. Tumor cells display major differences when compared to their natural counterparts, due to alterations in fundamental cellular processes such as glycosylation. Glycans are involved in tumor cell biology and they have been considered to be suitable cancer biomarkers. Thus, more selective cancer screening assays can be developed through the detection of specific altered glycans on the surface of circulating cancer cells. Currently, this is only possible through time-consuming assays. In this work, we propose the "intelligent" Lab on Fiber (iLoF) device, that has a high-resolution, and which is a fast and portable method for tumor single-cell type identification and isolation. We apply an Artificial Intelligence approach to the back-scattered signal arising from a trapped cell by a micro-lensed optical fiber. As a proof of concept, we show that iLoF is able to discriminate two human cancer cell models sharing the same genetic background but displaying a different surface glycosylation profile with an accuracy above 90% and a speed rate of 2.3 seconds. We envision the incorporation of the iLoF in an easy-to-operate microchip for cancer identification, which would allow further biological characterization of the captured circulating live cells.

2020

Femtosecond laser direct written off-axis fiber Bragg gratings for sensing applications

Autores
Viveiros, D; Amorim, VA; Maia, JM; Silva, S; Frazao, O; Jorge, PAS; Fernandes, LA; Marques, PVS;

Publicação
Optics and Laser Technology

Abstract
First order off-axis fiber Bragg gratings (FBGs) were fabricated in a standard single mode fiber (SMF-28e) through femtosecond laser direct writing. A minimum offset distance between the grating and core center of 2.5 µm was found to create a multimode section, which supports two separate fiber modes (LP0,1 and LP1,1), each split into two degenerate polarization modes. The resulting structure breaks the cylindrical symmetry of the fiber, introducing birefringence (˜10-4) resulting in a polarization dependent Bragg wavelength for each mode. Based on the modal and birefringence behavior, three off-axis FBGs were fabricated with 3.0, 4.5 and 6.0 µm offsets from the core center, and then characterized in strain, temperature, and curvature. The tested off-axis FBGs exhibited a similar strain sensitivity of ~1.14 pm/µ? and a temperature sensitivity of ~12 pm/C. The curvature and orientation angle were simultaneously monitored by analyzing the intensity fluctuation and the wavelength shift of the LP1,1 Bragg resonance. A maximum curvature sensitivity of 0.53 dB/m-1 was obtained for the off-axis FBG with a 3.0 µm offset. © 2020 Elsevier Ltd

2020

Author Correction: iLoF: An intelligent Lab on Fiber Approach for Human Cancer Single-Cell Type Identification

Autores
Paiva, JS; Jorge, PAS; Ribeiro, RSR; Balmaña, M; Campos, D; Mereiter, S; Jin, C; Karlsson, NG; Sampaio, P; Reis, CA; Cunha, JPS;

Publicação
Scientific Reports

Abstract

2020

Temperature Stability and Spectral Tuning of Long Period Fiber Gratings Fabricated by Femtosecond Laser Direct Writing

Autores
Viveiros, D; de Almeida, JMMM; Coelho, L; Vasconcelos, H; Maia, JM; Amorim, VA; Jorge, PAS; Marques, PVS;

Publicação
Sensors

Abstract
Long period fiber gratings (LPFGs) were fabricated in a standard single mode fiber (SMF-28e) through femtosecond (fs) laser direct writing. LPFGs with longer and shorter periods were fabricated, which allows coupling from the fundamental core mode to lower and higher order asymmetric cladding modes (LP1,6 and LP1,12, respectively). For the grating periods of 182.7 and 192.5 µm, it was verified that the LP1,12 mode exhibits a TAP at approximately 1380 and 1448 nm in air and water, respectively. Characterization of the LPFGs subjected to high-temperature thermal treatment was accomplished. Fine-tuning of the resonance band’s position and thermal stability up to 600 °C was shown. The temperature sensitivity was characterized for the gratings with different periods and for different temperature ranges. A maximum sensitivity of -180.73, and 179.29 pm/°C was obtained for the two resonances of the 182.7 µm TAP LPFG, in the range between 250 and 600 °C.

2019

Preface

Autores
Lechuga, L; Raptis, I; Jorge, P; Cusano, A;

Publicação
Optics and Laser Technology

Abstract

Teses
supervisionadas

2019

Fiber Laser Plasma Spectroscopy for Real-Time

Autor
Miguel Fernandes Soares Ferreira

Instituição
UP-FCUP

2019

Fast prototyping of advanced sensing devices using three-dimensional direct writing with femtosecond laser

Autor
Vítor Alexandre Oliveira Amorim

Instituição
UP-FCUP

2019

Development of differential optrodes for highly sensitive and reliable chemical sensing

Autor
João Pedro Sampaio Mendes

Instituição
UP-FCUP

2019

Optical fibre tweezers for trapping and manipulation of sub-­micrometre particles

Autor
Sandra Cristina Martins Rodrigues

Instituição
UP-FCUP

2019

Fabrication of opticals Ensing devices by 3D laser micromachining

Autor
Carlos Duarte Rodrigues Viveiros

Instituição
UP-FCUP