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Purpose: To aggregate, interpret, and synthesize findings from qualitative studies on patients' experiences with chemotherapy-induced peripheral neuropathy (CIPN). Methods: A qualitative metasynthesis was conducted following the thematic synthesis approach of Thomas & Harden. A systematic literature search was performed in MEDLINE, CINAHL, Psychology and Behavioral Sciences Collection, and Scopus, including studies published up to December 2024. Two researchers independently conducted the screening and data extraction. They also independently evaluated the quality of the included studies. The data from these studies were then thematically analyzed and synthesized using Dorothea Orem's model. Results: Eighteen studies were included. Four main categories were identified: (1) Physical and Functional Impact of CIPN, (2) Emotional and Psychological Impact, (3) Coping Strategies and Self-management, and (4) Support and Barriers to Health. The findings revealed distinct self-care deficits related to functional limitations, emotional distress, and coping challenges. Utilizing Orem's Nursing Theory of Self-Care Deficit, these deficits were mapped onto different levels of nursing intervention, ranging from compensatory support to educational and self-management strategies, emphasizing an action-oriented approach in patient care. Conclusions: This metasynthesis highlights the complex and multidimensional effects of peripheral neuropathy on the lives of cancer patients. Applying Orem's model underscores the critical role of nurses in addressing healthcare system gaps, functional impairments, and long-term adaptation challenges to enhance supportive care for individuals suffering from CIPN.

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Radon (Rn-222) is a unique atmospheric tracer, since it is an inert gaseous radionuclide with a predominantly terrestrial source and a short half-life (3.8232 (8) d), enabling quantification of the relative degree of recent (< 21 d) terrestrial influences on marine air masses. High quality measurements of atmospheric radon activity concentration in remote oceanic locations enable the most accurate identification of baseline conditions. Observations of GHGs under baseline conditions, representative of hemispheric background values, are essential to characterise long-term changes in hemispheric-mean GHG concentrations, differentiate between natural and anthropogenic GHG sources, and improve understanding of the global carbon budget.The EU-funded project NuClim (Nuclear observations to improve Climate research and GHG emission estimates) will establish world-leading high-quality atmospheric measurements of radon activity concentration and of selected GHG concentrations (CO2, and CH4) at a remote oceanic location, the Eastern North Atlantic (ENA) facility, managed by the Atmospheric Radiation Measurement (ARM) programme (Office of Science from the U.S. Department of Energy), located on Graciosa Island (Azores archipelago), near the middle of the north Atlantic Ocean. These observations will provide an accurate, time-varying atmospheric baseline reference for European greenhouse gas (GHG) levels, enabling a clearer distinction between anthropogenic emissions and slowly changing background levels. NuClim will also enhance measurement of atmospheric radon activity concentration at the Mace Head Station, allowing the identification of latitudinal gradients in baseline atmospheric composition, and supporting the evaluation of the performance of GHG mitigation measures for countries in the northern hemisphere.The high-quality nuclear and GHG observations from NuClim, and the resulting classification of terrestrial influences on marine air masses, will assist diverse climate and environmental studies, including the study of pollution events, characterisation of marine boundary layer clouds and aerosols, and exploration of the impact of natural planktonic communities on GHG emissions. This poster presents an overview of NuClim, outlines the project objectives and methodologies, and summarises the relevant data products that will be made available to the climate community.Project NuClim received funding from the EURATOM research and training program 2023-2025 under Grant Agreement No 101166515.

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