Abstract
This paper proposes a novel approach for the provision of non-frequency ancillary service (AS) by consumers connected to low-voltage distribution networks. The proposed approach considers an asymmetric pool-based local market for AS negotiation, allowing consumers to set a flexibility quantity and desired price to trade. A case study with 98 consumers illustrates the proposed market-based non-frequency AS provision approach. Also, three different strategies of consumers' participation are implemented and tested in a real low-voltage distribution network with radial topology. It is shown that consumers can make a profit from the sale of their flexibility while contributing to keeping the network power losses, voltage, and current within pre-defined limits. Ultimately, the results demonstrate the value of AS coming directly from end-users.

Abstract
Tension remains between the observed and modeled properties of substellar objects, but objects in binary orbits, with known dynamical masses, can provide a way forward. HD 72946 B is a recently imaged brown dwarf companion to a nearby, solar-type star. We achieve similar to 100 mu as relative astrometry of HD 72946 B in the K band using VLTI/GRAVITY, unprecedented for a benchmark brown dwarf. We fit an ensemble of measurements of the orbit using orbitize! and derive a strong dynamical mass constraint M B = 69.5 +/- 0.5 M Jup assuming a strong prior on the host star mass M A = 0.97 +/- 0.01 M circle dot from an updated stellar analysis. We fit the spectrum of the companion to a grid of self-consistent BT-Settl-CIFIST model atmospheres, and perform atmospheric retrievals using petitRADTRANS. A dynamical mass prior only marginally influences the sampled distribution of effective temperature, but has a large influence on the surface gravity and radius, as expected. The dynamical mass alone does not strongly influence retrieved pressure-temperature or cloud parameters within our current retrieval setup. Independently of the cloud prescription and prior assumptions, we find agreement within +/- 2 sigma between the C/O of the host (0.52 +/- 0.05) and brown dwarf (0.43-0.63), as expected from a molecular cloud collapse formation scenario, but our retrieved metallicities are implausibly high (0.6-0.8) in light of the excellent agreement of the data with the solar-abundance model grid. Future work on our retrieval framework will seek to resolve this tension. Additional study of low surface gravity objects is necessary to assess the influence of a dynamical mass prior on atmospheric analysis.

Abstract
Pathologies in concrete structures, such as cracks, splintering, efflorescence, corrosion spots, and exposed steel bars, can be visually evidenced on the concrete surface. This paper proposes a method for automatically detecting these pathologies from images of the concrete structure. The proposed method uses deep neural networks to detect pathologies in these images. This method results in time savings and error reduction. The paper presents results in detecting the pathologies from wide-angle images containing the overall structure and also for the specific pathology identification task for cropped images of the region of the pathology. Identifying pathologies in cropped images, the classification task could be performed with 99.4% accuracy using cross-validation and classifying cracks. Wide images containing no, one, or several pathologies in the same image, the case of pathology detection, could be analyzed with the YOLO network to identify five pathology classes. The results for detection with YOLO were measured with mAP, mean Average Precision, for five classes of concrete pathology, reaching 11.80% for fissure, 19.22% for fragmentation, 5.62% for efflorescence, 27.24% for exposed bar, and 24.44% for corrosion. Pathology identification in concrete photos can be optimized using deep learning.

Abstract
Regulated exocytosis consists of the fusion between vesicles and the plasma membranes, leading to the formation of a narrow fusion pore through which secretions exit the vesicle lumen into the extracellular space. An increase in the cytosolic concentration of free Ca2+ ([Ca2+](i)) is considered the stimulus of this process. However, whether this mechanism can be preserved in a simplified system of membrane lawns with docked secretory vesicles, devoid of cellular components, is poorly understood. Here, we studied peptide discharge from individual secretory vesicles docked at the plasma membrane, prepared from primary endocrine pituitary cells (the lactotrophs), releasing hormone prolactin. To label secretory vesicles, we transfected lactotrophs to express the fluorescent atrial natriuretic peptide (ANP.emd), previously shown to be expressed in and released from prolactin-containing vesicles. We used stimulating solutions containing different [Ca2+] to evoke vesicle peptide discharge, which appeared similar in membrane lawns and in intact stimulated lactotrophs. All vesicles examined discharged peptides in a subquantal manner, either exhibiting a unitary or sequential time course. In the membrane lawns, the unitary vesicle peptide discharge was predominant and slightly slower than that recorded in intact cells, but with a shorter delay with respect to the stimulation onset. This study revealed directly that Ca2+ triggers peptide discharge from docked single vesicles in the membrane lawns with a half-maximal response of similar to 8 mu M [Ca2+], consistent with previous whole-cell patch-clamp studies in endocrine cells where the rapid component of exocytosis, interpreted to represent docked vesicles, was fully activated at <10 mu M [Ca2+]. Interestingly, the sequential subquantal peptide vesicle discharge indicates that fluctuations between constricted and dilated fusion pore states are preserved in membrane lawns and that fusion pore regulation appears to be an autonomously controlled process.

Abstract
We consider a continuous lifetime model for investor whose lifetime is a random variable. We assume the investor has an access to the social welfare system, the financial market and the life insurance market. The investor aims to find the optimal strategies that maximize the expected utility obtained from consumption, investing in the financial market, buying life insurance, registering in the social welfare system, the size of his estate in the event of premature death and the size of his fortune at time of retirement if he lives that long. We use dynamic programming techniques to derive a second-order nonlinear partial differential equation whose solution is the maximum objective function. We use special case of discounted constant relative risk aversion utilities to find an explicit solutions for the optimal strategies. Finally, we have shown a numerical solution for the problem under consideration and study some properties for the optimal strategies.

Abstract
The adoption of smart grids is becoming a common reality worldwide. This new reality is starting to impact energy customers as they face a dynamic grid in which they can actively participate. However, if energy customers are not prepared to participate actively, they can have their energy costs increased. This paper provides a review of acceptance models and customer surveys around the world made to assess the customers' perception and willingness to participate in smart grids. Contributing to this assessment, this paper presents a survey undertaken in Portugal. The survey results demonstrate a willingness, from the customer's end, to actively participate in smart grid initiatives. It was found that 92.9% of participants are willing to plan their energy usage to face hourly energy prices and that 95.0% of participants are willing to accept an external control of at least one appliance, enabling direct load control demand response programs. Also, the results identified two cognitive tendencies, negativity bias, and loss aversion, which can impact how customers participate in smart grids. These cognitive tendencies and the literature acceptance models demonstrate the importance of conducting social science studies targeting smart grids to fully achieve the efficient participation of end customers.