Abstract
This paper discusses a rectifier inverter composed of two three-leg converters with equal and unequal dc-links voltages connected in series. The operation with equal dc-links voltages divides equally the voltages in each converter. On the other hand, the operation with unequal dc-links voltages increases the number of voltage levels and contributes to reduce harmonic distortion and power losses. Space-vector and level-shifted techniques are discussed. The balance of separated dc sources using redundant voltage vectors is addressed in this paper. A closed-loop controller is used to control the average value of the dc voltages. Simulation results compare power losses and harmonic distortion of three-leg and six-leg topologies. Experimental results are provided to validate the feasibility of the system.

Abstract
Cancer is characterised by somatic genetic variation, but the effect of the majority of non-coding somatic variants and the interface with the germline genome are still unknown. We analysed the whole genome and RNA-seq data from 1,188 human cancer patients as provided by the Pan-cancer Analysis of Whole Genomes (PCAWG) project to map cis expression quantitative trait loci of somatic and germline variation and to uncover the causes of allele-specific expression patterns in human cancers. The availability of the first large-scale dataset with both whole genome and gene expression data enabled us to uncover the effects of the non-coding variation on cancer. In addition to confirming known regulatory effects, we identified novel associations between somatic variation and expression dysregulation, in particular in distal regulatory elements. Finally, we uncovered links between somatic mutational signatures and gene expression changes, including TERT and LMO2, and we explained the inherited risk factors in APOBEC-related mutational processes. This work represents the first large-scale assessment of the effects of both germline and somatic genetic variation on gene expression in cancer and creates a valuable resource cataloguing these effects.

Abstract
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Abstract
The IPP4B workshop assembles a group of researchers from academia and industry - BBC R&D, Ericsson and MOG Technologies - to discuss the state of the art and together envisage future directions for in-programme personalisation in broadcasting. The workshop comprises one invited keynote, two invited presentations together with a paper and discussion sessions.

Abstract
Venous thromboembolism is a pathology that is responsible for high rates of morbidity and mortality in hospitals. An adequate thromboprophylaxis may contribute to an effective improvement of the well-being and safety of patients. One of the important factors for the prescription of a thromboprophylaxis is the determination of the risk of thromboembolism, which can be implemented in several ways, using different methodologies, namely by using risk scales. In this work, developed in the Hospital Center of Tras-os-Montes and Alto Douro, Portugal, we describe the development and implementation of an application with two scales for the assessment and stratification of the risk of thromboembolism, to be applied in hospitalized patients (Caprini scale) and in patients in ambulatory surgery (scale recommended by the Portuguese Ambulatory Surgery Association). The application was integrated into the hospital electronic health record system (SClinico).

Abstract
Availability is a major design issue that should play an important role when deploying and operating wireless sensor networks, specially for critical monitoring applications. Actually, sensing redundancy can be exploited to enhance the attainable availability level of sensor networks, since redundant nodes can replace faulty nodes. When employing camera enabled sensors, the perception of sensing redundancy is considerably changed" when compared to scalar sensors, with direct impact on network availability. In such way, some characteristics as deployment density, viewing angle and sensing range should be properly evaluated in wireless visual sensor networks, in order to better estimate the network availability. Nevertheless, when deploying visual sensors on occluded environments, viewed areas and resulted overlapping may be significantly altered, redefining sensing redundancy. We then propose an algorithm to automatically select redundant nodes in wireless visual sensor networks deployed on areas with occlusion, according to network configurations and application availability requirements. Additionally, an algorithm to adjust cameras' orientations in occluded environments is also proposed. Mathematical assessment of the proposed algorithms are performed, allowing the discussion of how parameters of deployed networks can influence applications monitoring availability.