2025
Authors
Saraiva, M; Garcez, J; da Silva, BT; Ferreira, IP; Oliveira, JC; Palma, I;
Publication
LIPIDS IN HEALTH AND DISEASE
Abstract
Background Cardiovascular disease (CVD) is a major cause of mortality worldwide, necessitating more refined strategies for risk assessment. Recently, lipoprotein(a) [Lp(a)] has gained attention for its distinctive role in atherosclerosis, yet its prevalence and impact for cardiovascular risk assessment are not well-documented in the Portuguese population. This study aimed to characterize Lp(a) levels in a real-world Portuguese cohort, investigating its prevalence and association with CVD risk. Methods Retrospective and cross-sectional study of adults who underwent serum Lp(a) analysis in a Portuguese hospital between August 2018 and June 2022. Demographic and anthropometric data, laboratory values, relevant comorbidities and lipid-lowering medication were collected. Results Of 1134 participants, 28.7% had elevated Lp(a) levels (> 125 nmol/L). A higher prevalence was observed in those with atherosclerotic cardiovascular disease (ASCVD) (45.9%) or a family history of premature CVD (41.9%). Additionally, a significant association was found between elevated Lp(a) levels and traditional CVD risk factors, including hypertension, dyslipidemia, and diabetes mellitus. Among those classified as having low-to-moderate CVD risk by (Systematic COronary Risk Evaluation 2) SCORE2, 55.7% exhibited high Lp(a) levels (> 75 nmol/L), suggesting a potential higher risk of CVD disease. Conclusions The prevalence of elevated Lp(a) in Portugal, notably among those with ASCVD or premature CVD history, is concerning. This study underscores the potential of Lp(a) assessment for a more comprehensive approach to cardiovascular risk assessment. This could improve the stratification of CVD risk and identify individuals who could benefit from early intensive management of their risk factors, ultimately reducing the burden of CVD and cardiovascular-related mortality.
2025
Authors
Kurteshi, R; Almeida, F;
Publication
INTERNATIONAL JOURNAL OF ENTREPRENEURIAL BEHAVIOR & RESEARCH
Abstract
Purpose - The objective of this study is to integrate various theories of identity within entrepreneurship and derive insights and propositions that enhance the understanding of how an incubation program influences the formation and development of entrepreneurial team identity. Design/methodology/approach - This study adopts a qualitative multiple case study design to explore how entrepreneurial team identity develops within ventures incubated at CEU iLab. The analysis is based primarily on interviews with individual entrepreneurs from five selected ventures, complemented by secondary data to enrich and contextualize the findings. Findings - The findings revealed the interconnections between entrepreneurial team formation processes, social interactions, networking, entrepreneurial team stability, feedback mechanisms, team dynamics and intrateam trust and legitimacy. Moreover, the cultivation of a culture defined by trust, open communication and the active integration of feedback mechanisms played a pivotal role in the creation of collaborative team environments. Furthermore, the process of building an entrepreneurial team is heavily reliant on shared vision, common values, complementary skill sets, intrateam trust and pre-existing relationships. Originality/value - This study addresses a notable gap in the existing literature by studying how entrepreneurial teams and individual entrepreneurial team members manage to form and develop their entrepreneurial identity. By focusing on the dynamic processes behind identity formation within teams, this research provides novel insights into the motivations that drive individuals and teams to engage in entrepreneurial activities. This focus on the interplay between identity and team processes represents a distinctive and timely addition to the field.
2025
Authors
Baratto, M; Crama, Y; Pedroso, JP; Viana, A;
Publication
EUROPEAN JOURNAL OF OPERATIONAL RESEARCH
Abstract
When each patient of a kidney exchange program has a preference ranking over its set of compatible donors, questions naturally arise surrounding the stability of the proposed exchanges. We extend recent work on stable exchanges by introducing and underlining the relevance of a new concept of locally stable, or L-stable, exchanges. We show that locally stable exchanges in a compatibility digraph are exactly the so-called local kernels (L-kernels) of an associated blocking digraph (whereas the stable exchanges are the kernels of the blocking digraph), and we prove that finding a nonempty L-kernel in an arbitrary digraph is NP-complete. Based on these insights, we propose several integer programming formulations for computing an L-stable exchange of maximum size. We conduct numerical experiments to assess the quality of our formulations and to compare the size of maximum L-stable exchanges with the size of maximum stable exchanges. It turns out that nonempty L-stable exchanges frequently exist in digraphs which do not have any stable exchange. All the above results and observations carry over when the concept of (locally) stable exchanges is extended to the concept of (locally) strongly stable exchanges.
2025
Authors
Fernandes, F; Lopes, JP; Moreira, C;
Publication
IET GENERATION TRANSMISSION & DISTRIBUTION
Abstract
This work proposes an innovative methodology for the optimal placement of grid-forming converters (GFM) in converter-dominated grids while accounting for multiple stability classes. A heuristic-based methodology is proposed to solve an optimisation problem whose objective function encompasses up to 4 stability indices obtained through the simulation of a shortlist of disturbances. The proposed methodology was employed in a modified version of the 39-bus test system, using DigSILENT Power Factory as the simulation engine. First, the GFM placement problem is solved individually for the different stability classes to highlight the underlying physical phenomena that explain the optimality of the solutions and evidence the need for a multi-class approach. Second, a multi-class approach that combines the different stability indices through linear scalarisation (weights), using the normalised distance of each index to its limit as a way to define its importance, is adopted. For all the proposed fitness function formulations, the method successfully converged to a balanced solution among the various stability classes, thereby enhancing overall system stability.
2025
Authors
Rasul, A; Teixeira, R; Baptista, J;
Publication
Energies
Abstract
To achieve lower switching losses and higher frequency capabilities in converter design, researchers worldwide have been investigating Silicon carbide (SiC) modules and MOSFETs. In power electronics, wide bandgap devices such as Silicon carbide are essential for creating more efficient, higher-density, and higher-power-rated converters. Devices like SiC and Gallium nitride (GaN) offer numerous advantages in power electronics, particularly by influencing parasitic capacitance and inductance in printed circuit boards (PCBs). A review paper on Silicon carbide converter designs using coupled inductors provides a comprehensive analysis of the advancements in SiC-based power converter technologies. Over the past decade, SiC converter designs have demonstrated both efficiency and reliability, underscoring significant improvements in performance and design methodologies over time. This review paper examines developments in Silicon carbide converter design from 2014 to 2024, with a focus on the research conducted in the past ten years. It highlights the advantages of SiC technology, techniques for constructing converters, and the impact on other components. Additionally, a bibliometric analysis of prior studies has been conducted, with a particular focus on strategies to minimize switching losses, as discussed in the reviewed articles. © 2025 by the authors.
2025
Authors
Rodrigues Ferraz Esteves, AR; Campos Magalhães, EM; Bernardes De Almeida, G;
Publication
SAE Technical Papers
Abstract
Silent motors are an excellent strategy to combat noise pollution. Still, they can pose risks for pedestrians who rely on auditory cues for safety and reduce driver awareness due to the absence of the familiar sounds of combustion engines. Sound design for silent motors not only tackles the above issues but goes beyond safety standards towards a user-centered approach by considering how users perceive and interpret sounds. This paper examines the evolving field of sound design for electric vehicles (EVs), focusing on Acoustic Vehicle Alerting Systems (AVAS). The study analyzes existing AVAS, classifying them into different groups according to their design characteristics, from technical concerns and approaches to aesthetic properties. Based on the proposed classification, an (adaptive) sound design methodology, and concept for AVAS are proposed based on state-of-the-art technologies and tools (APIs), like Wwise Automotive, and integration through a functional prototype within a virtual environment. We validate our solution by conducting user tests focusing on EV sound perception and preferences in rural and urban environments. Results showed participants preferred nature-like and melodic sounds with a wide range of frequencies, emphasizing 1000Hz, in rural areas, for the AVAS. For the interior experience, melodic, reliable, and relaxing sounds with a frequency range from 200Hz to 500Hz. In urban areas, melodic, futuristic, but not overpowering sounds (80Hz to 700Hz) with balanced frequencies at high speeds were chosen for the car's exterior. In the interior, melodic, futuristic, and combustion engine-like sounds with a low frequencies background and higher frequencies at high speeds were also preferred. © 2025 SAE International. All Rights Reserved.
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