Abstract
The U-Net is one of the most fundamental architectural advancements in the deep learning era. It is a crucial tool for image segmentation, especially for biomedical modalities. The research community seems to interpret the effectiveness of neural architectural search (such as the nn-U-Net) as evidence that architectural enhancements proposed since its debut are mostly unnecessary. We argue that there are still network-in-network primitives that can be leveraged to further enhance its performance, focusing on the squeeze-and-excitation (SE) pathway specifically in this paper. Specifically, we study its use of global descriptors, since it should be at odds with the spatial resolution required for dense-prediction tasks. It is theorized in the literature that performance is probably gained from some implicit ability of the learned excitations to filter supposedly uninformative channels during training. We explain this almost unreasonable success through an analysis of the empirical estimates of the excitation covariance matrix. Our analysis also directly contradicts the above conjecture - the most effective SE approach actually displayed the less extreme filtering behaviour, weighing all channels much closer to the mean (0.5). Our experiments are conducted in three diverse, staple biomedical modalities: dermoscopy, colonoscopy, and ultrasound. © 2025 European Signal Processing Conference, EUSIPCO. All rights reserved.

Abstract
Artificial intelligence (AI) holds significant potential for enhancing quality of gastrointestinal (GI) endoscopy, but the adoption of AI in clinical practice is hampered by the lack of rigorous standardisation and development methodology ensuring generalisability. The aim of the Quality Assessment of pre-clinical AI studies in Diagnostic Endoscopy (QUAIDE) Explanation and Checklist was to develop recommendations for standardised design and reporting of preclinical AI studies in GI endoscopy. The recommendations were developed based on a formal consensus approach with an international multidisciplinary panel of 32 experts among endoscopists and computer scientists. The Delphi methodology was employed to achieve consensus on statements, with a predetermined threshold of 80% agreement. A maximum three rounds of voting were permitted. Consensus was reached on 18 key recommendations, covering 6 key domains: data acquisition and annotation (6 statements), outcome reporting (3 statements), experimental setup and algorithm architecture (4 statements) and result presentation and interpretation (5 statements). QUAIDE provides recommendations on how to properly design (1. Methods, statements 1-14), present results (2. Results, statements 15-16) and integrate and interpret the obtained results (3. Discussion, statements 17-18). The QUAIDE framework offers practical guidance for authors, readers, editors and reviewers involved in AI preclinical studies in GI endoscopy, aiming at improving design and reporting, thereby promoting research standardisation and accelerating the translation of AI innovations into clinical practice.

Abstract

Abstract
The medical imaging field contends with limited data for training deep learning (DL) models. Our study evaluated traditional data augmentation (DA) and Generative Adversarial Networks (GANs) in enhancing DL models for identifying stomach precancerous lesions. Classic DA consistently outperformed GAN-based methods with ResNet50 (0.94 vs 0.93 accuracy) and ViT (0.85 vs 0.84 accuracy) models achieving higher accuracy and other performance metrics with DA compared to GANs. Despite this, GAN augmentation showed significant improvements when compared to train with the original dataset, highlighting its role in diversifying datasets and aiding generalization across different medical imaging datasets. Combining both augmentation techniques can enhance model robustness and generalisation capabilities in DL applications for medical diagnostics, leveraging DA's consistency and GANs' diversity.

Abstract
The integration of artificial intelligence (AI) in medical diagnostics represents a significant advancement in managing upper gastrointestinal (GI) cancer, which is a major cause of global cancer mortality. Specifically for gastric cancer (GC), chronic inflammation causes changes in the mucosa such as atrophy, intestinal metaplasia (IM), dysplasia, and ultimately cancer. Early detection through endoscopic regular surveillance is essential for better outcomes. Foundation models (FMs), which are machine or deep learning models trained on diverse data and applicable to broad use cases, offer a promising solution to enhance the accuracy of endoscopy and its subsequent pathology image analysis. This review explores the recent advancements, applications, and challenges associated with FMs in endoscopy and pathology imaging. We started by elucidating the core principles and architectures underlying these models, including their training methodologies and the pivotal role of large-scale data in developing their predictive capabilities. Moreover, this work discusses emerging trends and future research directions, emphasizing the integration of multimodal data, the development of more robust and equitable models, and the potential for real-time diagnostic support. This review aims to provide a roadmap for researchers and practitioners in navigating the complexities of incorporating FMs into clinical practice for the prevention/management of GC cases, thereby improving patient outcomes.