Abstract

Abstract

Abstract

Abstract

Abstract
Federated Learning (FL) enables decentralized model training while preserving data privacy but remains susceptible to poisoning attacks. Malicious clients can manipulate local data or model updates, threatening FL’s reliability, especially in privacy-sensitive domains like healthcare and finance. While client-side optimization algorithms play a crucial role in training local models, their resilience to such attacks is underexplored. This study empirically evaluates the robustness of three widely used optimization algorithms: SGD, Adam, and RMSProp—against label-flipping attacks (LFAs) in image classification tasks using Convolutional Neural Networks (CNNs). Through 900 individual runs in both federated and centralized learning (CL) settings, we analyze their performance under Independent and Identically Distributed (IID) and Non-IID data distributions. Results reveal that SGD is the most resilient, achieving the highest accuracy in 87% of cases, while Adam performs best in 13%. Additionally, centralized models outperform FL on CIFAR-10, whereas FL excels on Fashion-MNIST, highlighting the impact of dataset characteristics on adversarial robustness. © 2025 Elsevier B.V., All rights reserved.

Abstract
Providing healthcare professionals with quick access to structured standardized information enables comprehensive analysis and improves clinical decision-making. However, an important part of the records in health institutions is in the form of free text. This paper proposes a pipeline that automatically extracts medical information from Electronic Medical Records (EMRs), based on large language models (LLMs) and a domain ontology defined and validated in collaboration with a medical expert. The output is a knowledge graph of clinical narratives that can be used to search through repositories of EMRs or discover new facts. To promote the standardization of the extracted medical terms, we link them to existing international coding systems using biomedical repositories (UMLS - Unified Medical Language System and BioPortal - Biomedical Ontology Repository). We showcase our approach on a set of Portuguese clinical texts of cases of Acute Myeloid Leukemia (AML) guided by one medical expert. We evaluate the quality of the extraction and of the knowledge graph. © 2025 Elsevier B.V., All rights reserved.