Abstract
Breast cancer conservative treatment (BCCT) is considered the gold standard of breast cancer treatment. However, aesthetic results are heterogeneous and difficult to evaluate in a standardised way. The limited reproducibility of subjective aesthetic evaluation in BCCT forced the research on objective methods. A recent computer system was developed to objectively and automatically evaluate the aesthetic result of BCCT In this system, the detection of the breast contour on the digital photograph of the patient is necessary to extract the features subsequently used in the evaluation process. In this paper we extend an algorithm based on the shortest path on a graph to detect automatically the breast contour. The advantage of graph algorithms is that they are guaranteed to find the global optimum of the problem; the difficulty is that they make it hard to enforce shape constraints. We define and compare different techniques to introduce the a priory knowledge of the mammary contour. Experimental results show that the proposed techniques consistently outperform the base method.

Abstract
The cosmetic result is an important endpoint for breast cancer conservative treatment (BCCT), but the verification of this outcome remains without a standard. Objective assessment methods are preferred to overcome the drawbacks of subjective evaluation. In this paper a novel algorithm is proposed, based on support vector machines, for the classification of ordinal categorical data. This classifier is then applied as a new methodology for the objective assessment of the aesthetic result of BCCT. Based on the new classifier, a semi-objective score for quantification of the aesthetic results of BCCT was developed, allowing the discrimination of patients into four classes.

Abstract
The automatic detection and segmentation of the pectoral muscle in the medio-lateral oblique view of mammograms is essential for further analysis of breast anormalies. However, it is still a very difficult task since the sizes, shapes and intensity contrasts of pectoral muscles change greatly from image to image. In this paper, an algorithm based on the shortest path on a graph is proposed to automatically detect the pectoral muscle contour. To overcome the difficulties of searching for the path between a lateral and the top margins of the image, this is first transformed, using polar coordinates. In the transformed image, the muscle boundary in amongst the shortest paths between the top and the bottom rows. A comprehensive comparison with manually-drawn contours reveals the strength of the proposed method.

Abstract
Automatic pectoral muscle removal on mediolateral oblique view of mammogram is an essential step for many mammographic processing algorithms. However, the wide variability in the position of the muscle contour, together with the similarity between in muscle and breast tissues makes the detection a difficult task. In this paper, we propose a two step procedure to detect the muscle contour. In a first step, the endpoints of the contour are predicted with a pair of support vector regression models; one model is trained to predict the intersection point of the contour with the top row while the other is designed for the prediction of the endpoint of the contour on the left column. Next, the muscle contour is computed as the shortest path between the two endpoints. A comprehensive comparison with manually-drawn contours reveals the strength of the proposed method.

Abstract
Breast Cancer Conservative Treatment (BCCT) is considered nowadays to be the most widespread form of locor-regional breast cancer treatment. However, aesthetic results are heterogeneous and difficult to evaluate in a standardized way. The limited reproducibility of subjective aesthetic evaluation in BCCT motivated the research towards objective methods. A recent computer system (BCCT. core) was developed to objectively and automatically evaluate the aesthetic result of BCCT. The system is centered on a support vector machine (SVM) classifier with a radial basis function (RBF) used to predict the overall cosmetic result from features computed on a digital photograph of the patient. However, this classifier is not ideal for the interpretation of the factors being used in the prediction. Therefore, an often suggested improvement is the interpretability of the model being used to assess the overall aesthetic result. In the current work we investigate the accuracy of different interpretable methods against the model currently deployed in the BCCT. core software. We compare the performance of decision trees and linear classifiers with the RBF SVM currently in BCCT. core. In the experimental study, these interpretable models shown a similar accuracy to the currently used RBF SVM, suggesting that the later can be replaced without sacrificing the performance of the BCCT.core.

Abstract