Abstract
Introduction: The improvements made to healthcare IT systems made over the past years led to the creation of a multitude of different applications essential to the institutions daily operations. Aim: We aim to create and install a system capable of displaying production metrics for healthcare management with little requirements, efforts and software providers involved. Methods: We propose a system capable of displaying production metrics for healthcare facilities, by extracting HL7 messages and other eHealth relevant protocols directly from the institution's network infrastructure. Our system is then able to populate a knowledge database with meaningful information derived from the gathered data. Results: Our system is currently being tested on a large healthcare facility where it extracts and analyses a daily average of 44,000 HL7 messages. The system is currently capable of inferring and displaying the daily distribution of healthcare related activities such as laboratory orders or even relevant billing information. Conclusion: HL7 messages moving over the network contain valuable information that can then be used to assess many relevant production metrics for the entire facility and from otherwise non-interoperable production systems that, in most cases, can only be seen as black boxes by other system integrators.

Abstract
The development of eHealth technologies over the last few years has been pushing healthcare institutions to evolve their own infrastructures. Along with this evolution, critical systems now need to use communication standards such as HL7 or DICOM in order to exchange information in a more meaningful and efficient way. However, healthcare institutions often experience complications when different systems communicate directly even when using communication standards. We aim to assess the quality of the data present in HL7 messages exchanged between different critical systems in a large healthcare facility and therefore propose an integration infrastructure that allows a real time and centralized way to manage, route and monitor the integration flows between various systems.

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Determining the frequency of small subgraphs is an important graph mining primitive. One major class of algorithms for this task is based upon the enumeration of all sets of k connected nodes. These are known as network-centric algorithms. FAst Subgraph Enumeration (FaSE) is a exact algorithm for subgraph counting that contrasted with its past approaches by performing the isomorphism tests while doing the enumeration, encapsulating the topological information in a g-trie and thus largely reducing the number of required isomorphism tests. Our goal with this paper is to expand this approach by providing an approximate algorithm, which we called Rand-FaSE. It uses an unbiased sampling estimator for the number of subgraphs of each type, allowing an user to trade some accuracy for even faster execution times. We tested our algorithm on a set of representative complex networks, comparing it with the exact alternative, FaSE. We also do an extensive analysis by studying its accuracy and speed gains against previous sampling approaches. With all of this, we believe FaSE and Rand-FaSE pave the way for faster network-centric census algorithms.

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