Abstract
This paper studies the use of non-invasive acoustic emission recordings for clinical device tracking. In particular, audio signals recorded at the proximal end of a needle are used to detect perforation events that occur when the needle tip crosses internal tissue layers. A comparative study is performed to assess the capacity of different features and envelopes in detecting perforation events. The results obtained from the considered experimental setup show a statistically significant correlation between the extracted envelopes and the perforation events, thus leading the way for future development of perforation detection algorithms.

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Google Ads is a powerful tool for companies wishing to gain visibility on Google searches, as it offers impression privileges for advertisers, by featuring the ad above the organic results listing. This chapter contributes to the optimization of Google Ads campaigns. It includes an empirical study with a sample of marketing professionals exploring their views on the challenges of Google Ads as a digital marketing tool. According to the participants in this study, Google Ads campaign profitability depends, largely, on the ability to choose a keyword pool that achieves the company's goals. Moreover, the complexity of these pay-per-click decisions, the costs involved, and its business implications demand more reasoned, quantified, and, if possible, optimized solutions. The chapter develops linear programming optimization models based on impressions, clicks, conversions, and billing. The models are tested on a real example using Excel optimization add-ins.