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About

About

Aurélio Campilho is Professor in the Department of Electrical and Computer Engineering, Faculty of Engineering, University of Porto, Portugal. He is a Senior Member of the IEEE – The Institute of Electrical and Electronics Engineers. He is coordinator of the Center for Biomedical Engineering Research (C-BER) and develops research at the Biomedical Imaging Lab from C-BER from INESC TEC – Institute for Systems and Computer Engineering, Technology and Science. His teaching activities are in the  courses: Bioengineering Master Degree: Introduction to Scientific Computing, Biomedical Image Analysis and Computer-aided Diagnosis; Doctoral Degree in Electrical and Computer Engineering: Image Analysis and Recognition. His current research interests include the areas of biomedical engineering, medical image analysis, image processing and computer vision, particularly in Computer-aided Diagnosis applied in several imaging modalities, including ophthalmic images, carotid ultrasound imaging and computed tomography of the lung. He is General Chair of the series of International Conferences on Image Analysis and Recognition (ICIAR).

Interest
Topics
Details

Details

  • Name

    Aurélio Campilho
  • Role

    Affiliated Researcher
  • Since

    01st January 2014
  • Nationality

    Portugal
  • Contacts

    +351222094106
    aurelio.campilho@inesctec.pt
006
Publications

2022

Lesion-Based Chest Radiography Image Retrieval for Explainability in Pathology Detection

Authors
Pedrosa, J; Sousa, P; Silva, J; Mendonca, AM; Campilho, A;

Publication
PATTERN RECOGNITION AND IMAGE ANALYSIS (IBPRIA 2022)

Abstract

2022

Assessing clinical applicability of COVID-19 detection in chest radiography with deep learning

Authors
Pedrosa, J; Aresta, G; Ferreira, C; Carvalho, C; Silva, J; Sousa, P; Ribeiro, L; Mendonca, AM; Campilho, A;

Publication
SCIENTIFIC REPORTS

Abstract
The coronavirus disease 2019 (COVID-19) pandemic has impacted healthcare systems across the world. Chest radiography (CXR) can be used as a complementary method for diagnosing/following COVID-19 patients. However, experience level and workload of technicians and radiologists may affect the decision process. Recent studies suggest that deep learning can be used to assess CXRs, providing an important second opinion for radiologists and technicians in the decision process, and super-human performance in detection of COVID-19 has been reported in multiple studies. In this study, the clinical applicability of deep learning systems for COVID-19 screening was assessed by testing the performance of deep learning systems for the detection of COVID-19. Specifically, four datasets were used: (1) a collection of multiple public datasets (284.793 CXRs); (2) BIMCV dataset (16.631 CXRs); (3) COVIDGR (852 CXRs) and 4) a private dataset (6.361 CXRs). All datasets were collected retrospectively and consist of only frontal CXR views. A ResNet-18 was trained on each of the datasets for the detection of COVID-19. It is shown that a high dataset bias was present, leading to high performance in intradataset train-test scenarios (area under the curve 0.55–0.84 on the collection of public datasets). Significantly lower performances were obtained in interdataset train-test scenarios however (area under the curve > 0.98). A subset of the data was then assessed by radiologists for comparison to the automatic systems. Finetuning with radiologist annotations significantly increased performance across datasets (area under the curve 0.61–0.88) and improved the attention on clinical findings in positive COVID-19 CXRs. Nevertheless, tests on CXRs from different hospital services indicate that the screening performance of CXR and automatic systems is limited (area under the curve < 0.6 on emergency service CXRs). However, COVID-19 manifestations can be accurately detected when present, motivating the use of these tools for evaluating disease progression on mild to severe COVID-19 patients. © 2022, The Author(s).

2022

Carotid Ultrasound Boundary Study (CUBS): Technical considerations on an open multi-center analysis of computerized measurement systems for intima-media thickness measurement on common carotid artery longitudinal B-mode ultrasound scans

Authors
Meiburger, KM; Marzola, F; Zahnd, G; Faita, F; Loizou, CP; Laine, N; Carvalho, C; Steinman, DA; Gibello, L; Bruno, RM; Clarenbach, R; Francesconi, M; Nicolaides, AN; Liebgott, H; Campilho, A; Ghotbi, R; Kyriacou, E; Navab, N; Griffin, M; Panayiotou, AG; Gherardini, R; Varetto, G; Bianchini, E; Pattichis, CS; Ghiadoni, L; Rouco, J; Orkisz, M; Molinari, F;

Publication
COMPUTERS IN BIOLOGY AND MEDICINE

Abstract
After publishing an in-depth study that analyzed the ability of computerized methods to assist or replace human experts in obtaining carotid intima-media thickness (CIMT) measurements leading to correct therapeutic decisions, here the same consortium joined to present technical outlooks on computerized CIMT measurement systems and provide considerations for the community regarding the development and comparison of these methods, including considerations to encourage the standardization of computerized CIMT measurements and results presentation. A multi-center database of 500 images was collected, upon which three manual segmentations and seven computerized methods were employed to measure the CIMT, including traditional methods based on dynamic programming, deformable models, the first order absolute moment, anisotropic Gaussian derivative filters and deep learning-based image processing approaches based on U-Net convolutional neural networks. An inter- and intra-analyst variability analysis was conducted and segmentation results were analyzed by dividing the database based on carotid morphology, image signal-to-noise ratio, and research center. The computerized methods obtained CIMT absolute bias results that were comparable with studies in literature and they generally were similar and often better than the observed inter- and intra-analyst variability. Several computerized methods showed promising segmentation results, including one deep learning method (CIMT absolute bias = 106 +/- 89 mu m vs. 160 +/- 140 mu m intra-analyst variability) and three other traditional image processing methods (CIMT absolute bias = 139 +/- 119 mu m, 143 +/- 118 mu m and 139 +/- 136 mu m). The entire database used has been made publicly available for the community to facilitate future studies and to encourage an open comparison and technical analysis

2022

Attention-driven Spatial Transformer Network for Abnormality Detection in Chest X-Ray Images

Authors
Rocha, J; Pereira, SC; Pedrosa, J; Campilho, A; Mendonca, AM;

Publication
2022 IEEE 35TH INTERNATIONAL SYMPOSIUM ON COMPUTER-BASED MEDICAL SYSTEMS (CBMS)

Abstract

2022

Retinal and choroidal vasoreactivity in central serous chorioretinopathy

Authors
Penas, S; Araujo, T; Mendonca, AM; Faria, S; Silva, J; Campilho, A; Martins, ML; Sousa, V; Rocha Sousa, A; Carneiro, A; Falcao Reis, F;

Publication
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Abstract
Purpose This study aims to investigate retinal and choroidal vascular reactivity to carbogen in central serous chorioretinopathy (CSC) patients. Methods An experimental pilot study including 68 eyes from 20 CSC patients and 14 age and sex-matched controls was performed. The participants inhaled carbogen (5% CO2 + 95% O-2) for 2 min through a high-concentration disposable mask. A 30 degrees disc-centered fundus imaging using infra-red (IR) and macular spectral domain optical coherence tomography (SD-OCT) using the enhanced depth imaging (EDI) technique was performed, both at baseline and after a 2-min gas exposure. A parametric model fitting-based approach for automatic retinal blood vessel caliber estimation was used to assess the mean variation in both arterial and venous vasculature. Choroidal thickness was measured in two different ways: the subfoveal choroidal thickness (SFCT) was calculated using a manual caliper and the mean central choroidal thickness (MCCT) was assessed using an automatic software. Results No significant differences were detected in baseline hemodynamic parameters between both groups. A significant positive correlation was found between the participants' age and arterial diameter variation (p < 0.001, r= 0.447), meaning that younger participants presented a more vasoconstrictive response (negative variation) than older ones. No significant differences were detected in the vasoreactive response between CSC and controls for both arterial and venous vessels (p = 0.63 and p = 0.85, respectively). Although the vascular reactivity was not related to the activity of CSC, it was related to the time of disease, for both the arterial (p = 0.02, r = 0.381) and venous (p = 0.001, r= 0.530) beds. SFCT and MCCT were highly correlated (r= 0.830, p < 0.001). Both SFCT and MCCT significantly increased in CSC patients (p < 0.001 and p < 0.001) but not in controls (p = 0.059 and 0.247). A significant negative correlation between CSC patients' age and MCCT variation (r = - 0.340, p = 0.049) was detected. In CSC patients, the choroidal thickness variation was not related to the activity state, time of disease, or previous photodynamic treatment. Conclusion Vasoreactivity to carbogen was similar in the retinal vessels but significantly higher in the choroidal vessels of CSC patients when compared to controls, strengthening the hypothesis of a choroidal regulation dysfunction in this pathology.

Supervised
thesis

2021

Detection of lung nodules in computed tomography images

Author
Guilherme Moreira Aresta

Institution
UP-FEUP

2021

Explainable Artificial Medical Intelligence for Automated Thoracic Pathology Screening

Author
Joana Maria Neves da Rocha

Institution
UP-FEUP

2021

Artificial Intelligence-based Decision Support Models for COVID-19 Detection

Author
Sofia Perestrelo de Vasconcelos Cardoso Pereira

Institution
UP-FCUP

2021

Multi-Objective Long-Term Transmission Expansion Planning

Author
Luiz Eduardo de Oliveira

Institution
UP-FEUP

2020

content based image retrieval as a computer aided diagnosis tool for radiologists

Author
José Ricardo Ferreira de Castro Ramos

Institution
UP-FEUP