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Publications

2018

Classification of Breast Cancer Histology Images Through Transfer Learning Using a Pre-trained Inception Resnet V2

Authors
Ferreira, CA; Melo, T; Sousa, P; Meyer, MI; Shakibapour, E; Costa, P; Campilho, A;

Publication
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

Abstract
Breast cancer is one of the leading causes of female death worldwide. The histological analysis of breast tissue allows for the differentiation of the tissue suspected to be abnormal into four classes: normal tissue, benign tumor, in situ carcinoma and invasive carcinoma. Automatic diagnostic systems can help in that task. In this sense, this work propose a deep neural network approach using transfer learning to classify breast cancer histology images. First, the added top layers are trained and a second fine-tunning is done on some feature extraction layers that are frozen previously. The used network is an Inception Resnet V2. In order to overcome the lack of data, data augmentation is performed too. This work is a suggested solution for the ICIAR 2018 BACH-Challenge and the accuracy is 0.76 in the blind test set. © 2018, Springer International Publishing AG, part of Springer Nature.

2018

Creation of Retinal Mosaics for Diabetic Retinopathy Screening: A Comparative Study

Authors
Melo, T; Mendonça, AM; Campilho, A;

Publication
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

Abstract
The creation of retinal mosaics from sets of fundus photographs can significantly reduce the time spent on the diabetic retinopathy (DR) screening, because through mosaic analysis the ophthalmologists can examine several portions of the eye at a single glance and, consequently, detect and grade DR more easily. Like most of the methods described in the literature, this methodology includes two main steps: image registration and image blending. In the registration step, relevant keypoints are detected on all images, the transformation matrices are estimated based on the correspondences between those keypoints and the images are reprojected into the same coordinate system. However, the main contributions of this work are in the blending step. In order to combine the overlapping images, a color compensation is applied to those images and a distance-based map of weights is computed for each one. The methodology is applied to two different datasets and the mosaics obtained for one of them are visually compared with the results of two state-of-the-art methods. The mosaics obtained with our method present good quality and they can be used for DR grading. © 2018, Springer International Publishing AG, part of Springer Nature.