Abstract

Abstract
With the ongoing increase of the network technologies' diversity and the integration of the user level applications, the legacy-style content-independent configuration of the security mechanisms cannot yields in efficient security solutions farther. Our work aims to contribute on the design of auto-reconfigurable (adaptive) security services that are capable to satisfy the application's security level required with minimal network resources' usage. In this paper we propose a new networkcentric security architecture design that relies on the current network security conditions and content-aware mechanisms. The architecture main functional blocks and the corresponding relationships are defined. This architecture shall supply three inter-domain composite user security services, named "public traffic", "secret content" and "private communication", as well as, attack source traceback and distributed access control functionalities.

Abstract

Abstract
We consider a real production planning problem occurring in a glass container manufacturing company. The goal is to minimise the average stock level during a planning horizon of one year, maintaining customers satisfaction and keeping the production at its maximum rate. Besides the production capacity, the main constraints considered are related to the number of setup changes in machines, which is restricted in each factory. The main goal is to find the best balance between the number of setups and the average stock level. We propose a decomposition of the problem into two interrelated problems: a lot-sizing problem and a scheduling problem. For each problem we propose a mathematical model that can be solved using a commercial solver package. To be an efficient managerial tool, the method should provide quickly good solutions. Therefore we solve the lot-sizing problem through a relax-and-fix heuristic and discuss the results. Copyright © 2011 Inderscience Enterprises Ltd.

Abstract
Excess weight may be related to the development of adverse cardiometabolic risk factors in children. The aim of this study was to evaluate the effect of a lifestyle intervention program (nutrition and exercise counseling) on anthropometric parameters and metabolic syndrome (MS) components in Portuguese overweight/obese children. A total of 83 overweight/obese children aged 7-9 years were assigned to a 1-year individual or group-based treatment (GT); 61 children (z-score BMI (zBMI): 1.93 +/- A 0.28; 27 boys and 34 girls) completed the program. Anthropometric and biochemical parameters were assessed at baseline, at 6 months and at 1 year. The overweight/obese children, compared to normal-weight ones, presented significantly higher blood pressure, total-cholesterol, total-cholesterol/high density lipoprotein cholesterol (HDL) ratio, triglycerides, Apolipoprotein B and C-reactive protein levels, while HDL and Apolipoprotein A-I were significantly lower. At baseline, the prevalence of MS was 16.4% in overweight/obese and 0% in normal-weight children. The number of components of MS was significantly higher in children with higher zBMI. Lifestyle intervention led to a significant improvement in zBMI, waist circumference/height ratio, HDL, triglycerides, Apolipoprotein A-I, and Apolipoprotein B levels. The prevalence of MS decreased to 14.8%. The GT intervention seems to be more successful, with a significant decrease in zBMI and an increase in HDL and a lower drop-out rate. Overweight/obese children have multiple risk factors associated with the MS. Lifestyle intervention, both individual and group-based treatment, led to an improvement in the degree of overweight/obesity and in MS components.

Abstract
The consequences of regulatory T cell (Treg) inhibition of interleukine 2 secretion are examined by mathematical modelling. We determine the analytic formula that describes the fine balance between Regulatory T cells and T cells at controlled and immune response equilibrium states. We demonstrate that cytokine dependent growth exhibits a quorum T cell population threshold that determines if immune responses develop on activation. We determine the analytic formulas of T cell proliferation thresholds that allow us to study the sensibility of the quorum growth thresholds controlling immune responses.