Abstract
HAL 9000 is an Intrusion Tolerant Systems (ITSs) Risk Manager, which assesses configuration risks against potential intrusions. It utilizes gathered threat knowledge and remains operational, even in the absence of updated information. Based on its advice, the ITSs can dynamically and proactively adapt to recent threats to minimize and mitigate future intrusions from malicious adversaries. Our goal is to reduce the risk linked to the exploitation of recently uncovered vulnerabilities that have not been classified and/or do not have a script to reproduce the exploit, considering the potential that they may have already been exploited as zero-day exploits. Our experiments demonstrate that the proposed solution can effectively learn and replicate National Vulnerability Database's evaluation process with 99% accuracy.

Abstract
Intervention studies have been explored to identify actions to effectively remediate indoor environmental quality (IEQ) problems and to improve people's health, well-being, comfort, and productivity. This study assessed a comprehensive set of IEQ indicators related to ventilation, air pollution, thermal comfort, illuminance, and noise for the first time in Portuguese office buildings. The purpose was to derive evidence-based corrective measures for a further environmental intervention program. The study monitored and surveyed 15 open-space offices from six modern office buildings in Porto (Portugal) during a workday between September and December 2022. Illuminance was of most concern among the assessed IEQ indicators since the measured levels were below the minimum limit required in 27% of the evaluated workplaces. For CO2, although mean concentrations were below 1000 ppm, absolute values exceeding that level were consistently registered in 20% of the offices during the afternoon period. Mean levels of PM2.5, PM10, and ultrafine particles exceeding the WHO guidelines were found in 13%, 7%, and 7% of the offices, respectively. The assessed thermal comfort levels were typically neutral, corresponding to an estimated mean of 6% of dissatisfied people. Based on the findings, an intervention plan was designed to be implemented in the further stages of this work. The priority interventions to test include relocation of printers (PM source removal), optimisation of ventilation rates (using real-time data from CO2 sensors), adjustment of desk positions to improve illuminance, and introduction of indoor plants.

Abstract
The integration of artificial intelligence (AI) in medical diagnostics represents a significant advancement in managing upper gastrointestinal (GI) cancer, which is a major cause of global cancer mortality. Specifically for gastric cancer (GC), chronic inflammation causes changes in the mucosa such as atrophy, intestinal metaplasia (IM), dysplasia, and ultimately cancer. Early detection through endoscopic regular surveillance is essential for better outcomes. Foundation models (FMs), which are machine or deep learning models trained on diverse data and applicable to broad use cases, offer a promising solution to enhance the accuracy of endoscopy and its subsequent pathology image analysis. This review explores the recent advancements, applications, and challenges associated with FMs in endoscopy and pathology imaging. We started by elucidating the core principles and architectures underlying these models, including their training methodologies and the pivotal role of large-scale data in developing their predictive capabilities. Moreover, this work discusses emerging trends and future research directions, emphasizing the integration of multimodal data, the development of more robust and equitable models, and the potential for real-time diagnostic support. This review aims to provide a roadmap for researchers and practitioners in navigating the complexities of incorporating FMs into clinical practice for the prevention/management of GC cases, thereby improving patient outcomes.

Abstract

Abstract
The research objective of this work is to develop and evaluate an enterprise architecture for rural accommodation in the Iberian Peninsula that responds to the demand of the remote labor market. Through an extensive literature review and the application of ArchiMate modeling, this study focuses on providing an enterprise architecture that promotes business resilience and environmental sustainability and boosts the local economy. The proposed enterprise architecture is remotely evaluated by experts, highlighting potential benefits, challenges, and areas for improvement. The results show that the proposed enterprise architecture has the potential to improve the long-term success of rural lodging businesses, enhance the customer experience, promote sustainability, and contribute to economic growth in rural areas through value exchange among stakeholders. The ArchiMate model provides a holistic perspective on stakeholder interactions and interoperability across all functional business areas: Customer Service, Product Management, Omnichannel Commerce, Human Resources, Business Strategy, Marketing, and Sustainability Management. The idea is to empower rural lodging businesses to create a better customer experience, achieve energy and environmental efficiency, contribute to local development, respond quickly to regulatory changes and compliance, and develop new revenue streams. The main goal is to improve offers, mitigate seasonal effects, and reverse the continuous cycle of decline in areas with low population density. Therefore, this ArchiMate modeling can be the initial basis for the digitization or expansion of the rural lodging industry in other geographies.

Abstract
The adoption of open innovation poses significant challenges that are important to explore. Studies in this field have mainly focused on exploring the causes of the failure of open innovation among large companies. This study addresses this research gap by employing a sample of 297 Portuguese small- and medium-sized enterprises (SMEs) to explore, through a quantitative study, whether the dimensions and causes of failure differ between large organizations and SMEs. A total of seven dimensions of causes of failure are considered, including strategy-related, organizational structure, organizational culture, knowledge and intellectual property management, management skill and action, resources, and interfirm collaboration. The findings reveal significant differences in four of these seven dimensions: the main causes of failure are related to the resources and management processes of open innovation in SMEs, while large companies face more challenges in the organizational structure and culture components. This study offers theoretical insights into the gaps in the literature to better understand the challenges facing open innovation. Furthermore, this study offers practical guidelines for SMEs to identify and mitigate these main obstacles, promoting better innovation management practices.