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Abstract
The environmental targets set by power sectors throughout the world are the main drivers toward increasing the share of variable renewable energy sources (VRESs). Growth of VRESs will lead to a higher demand for operational flexibility due to their stochastic nature. Traditionally, conventional generation units provide the major share of additional required flexibility that may result in a higher depreciation. Motivated by this challenge, this paper investigates the potential of Demand Response (DR) as an emerging alternative in systems with significant amounts of wind power. To this end, a comprehensive set of DR programs including tariff-based, incentive-based and combinational DR programs are considered in a stochastic network-constrained market clearing framework. Afterwards, various DR programs are prioritized taking into account the system operator's economic, technical, and environmental desires. Moreover, the sensitivity of different DR programs into customer's price elasticity of demand as well as the participation level are evaluated by means of several sensitivity analyses. The obtained results can provide a guideline for the system operators to opt the most effective DR program.

Abstract
Objective: Axial motor features are common in Parkinson's disease (PD). These include gait impairment and postural abnormalities, such as camptocormia. The response of these symptoms to deep brain stimulation (DBS) is variable and difficult to assess objectively. For the first time, this study analyzes the treatment outcomes of two PD patients with camptocormia that underwent bilateral subthalamic nucleus (STN)-DBS evaluated with disruptive technologies. Patients and methods: Two patients with PD and camptocormia who underwent STN-DBS were included. Gait parameters were quantitatively assessed before and after surgery by using the NeuroKinect system and the camptocormia angle was measured using the camptoapp. Results: After surgery, patient 1 improved 29 points in the UPDRS-III. His camptocormia angle was 68 degrees before and 38 degrees after surgery. Arm and knee angular amplitudes (117.32 +/- 7.47 vs 134.77 +/- 2.70; 144.51 +/- 7.47 vs 169.08 +/- 3.27) and arm swing (3.59 +/- 2.66 vs 5.40 +/- 1.76 cm) improved when compared with his pre-operative measurements. Patient 2 improved 22 points in the UPDRS-III after surgery. Her camptocormia mostly resolved (47 degrees before to 9 degrees after surgery). Gait analysis revealed improvement of stride length (0.29 +/- 0.03 vs 0.35 +/- 0.03 m), stride width (18.25 +/- 1.16 vs 17.9 +/- 0.84 cm), step velocity (0.91 +/- 0.57 vs 1.33 +/- 0.48 m/s), arm swing (4.51 +/- 1.01 vs 7.38 +/- 2.71 cm) and arm and hip angular amplitudes (131.57 +/- 2.45 degrees vs 137.75 +/- 3.18; 100.51 +/- 1.56 vs 102.18 +/- 1.77 degrees) compared with her preoperative results. Conclusion: The gait parameters and camptocormia of both patients objectively improved after surgery, as assessed by the two quantitative measurement systems. STN-DBS might have a beneficial effect on controlling axial posturing and gait, being a potential surgical treatment for camptocormia in patients with PD. However, further studies are needed to derive adequate selection criteria for this patient population.

Abstract
The latest forecasts for the Portuguese tourist industry show that it will represent 16% of the Portuguese GNP very soon and, for 2017, the State Statistical Office registered over 3.5 million guests visiting the North of Portugal and around 7.4 million overnight stays in the region's tourist accommodation, which makes it safe to say that investing in projects that foster a common language in business communication will not only result in tangible financial gains but also in improved multi-cultural and multilingual understanding. Companies need, thus, to communicate seamlessly in a fully internationalised and digital world challenges companies to meet the need to systematise and harmonise language to properly convey meaning, thus promoting successful business undertakings. Such a need, a direct consequence of the phenomenon of globalisation and internationalisation of scientific and technological knowledge, becomes clear in a region with all the necessary elements to anchor sustainable growth, namely the four locations classified as UNESCO's World Heritage sites (Porto's historic center, Alto Douro wine region, Oa Valley Archeological Park and GuimarSes Historic Center). "WiTo - Do you speak wine tourism?" is a project, supported by a PhD thesis, that aims at creating an electronic multilingual thesaurus the wine tourism experts will consider a useful tool for communicating with different publics (experts and non-experts). Thus, we will have to determine which subjects and technical know-how are considered core, complementary and cross-sectional to wine tourism, leading to the conceptual representation of wine tourism specialised language (which, in turn, will allow for structuring and harmonization of the linguistic heritage clearly visible in the area's terminology). This project aims at providing the necessary basis for optimising knowledge transfer (thus promoting a faster flow of technical and scientific information) and its implementation in tourism information systems and electronic support platforms. This article aims at giving an overview of the current research in this area and presenting WiTo by highlighting some of its preliminary results and discussing some of the open questions.