Abstract
This study analyzed the potential of proximal optical sensing as an effective approach for early disease detection. A compact, modular sensing system, combining direct UV–Vis spectroscopy with optical fibers, supported by a principal component analysis (PCA), was applied to evaluate the modifications promoted by the bacteria Xanthomonas euvesicatoria in tomato leaves (cv. cherry). Plant infection was achieved by spraying a bacterial suspension (108 CFU mL-1) until run-off occurred, and a similar approach was followed for the control group, where only water was applied. A total of 270 spectral measurements were performed on leaves, on five different time instances, including pre- and post-inoculation measurements. PCA was then applied to the acquired data from both healthy and inoculated leaves, which allowed their distinction and differentiation, three days after inoculation, when unhealthy plants were still asymptomatic.

Abstract
In the last two years, the world has gone through an unprecedented change in the most diverse dimensions (social, economic, and even political), leading that society had to adapt very quickly to the contingencies imposed by COVID-19. All organizations (independent of their area of activity) had to adjust their processes to respond, efficiently and effectively, to these constraints. In this context, companies with concerns in internationalization (those that are already internationalized and those in an internationalization process) have had to resort to technologies to support the change in their modus operandi. The digital transformation (until now had an essential role in the transformation of organizations, but which was in a relatively slow implementation process) started to perform, in an accelerated way, the base of work for the heads of the organizations to be able to respond to these challenges. In this context, the transformation of the business model, supported by digital technology, has been documented as one of the strategies used to respond to disruptive environmental changes, particularly technologies that help companies identify new business practices. This study aims to find evidence of the importance of integrating and influencing technological innovations in the practice of international business strategy before and during COVID-19 pandemic. The results show the influence of the digitalization on the business strategies.

Abstract
Recently, research concerning the navigation of Autonomous Surface Vehicles (ASVs) has been increasing. However, a big scale implementation of these vessels is still held back by a plethora of challenges such as multi-object tracking. This article presents the development of a tracking model through transfer learning techniques, based on referenced object trackers for urban scenarios. The work consisted in training a neural network through deep learning techniques, including data association and comparison of three different optimisers, Adadelta, Adam and SGD, determining the best hyper-parameters to maximise the training efficiency. The developed model achieved decent performance at tracking large vessels in the ocean, being successful even in harsh lighting conditions and lack of image focus.

Abstract
Compared to rodents, sheep offer several attractive features as an experimental model for testing different medical and surgical interventions related to pathological gait caused by neurological diseases and injuries. To use sheep for development of novel treatment strategies in the field of neuroscience, it is key to establish the relevant kinematic features of locomotion in this species. To use sheep for development of novel treatment strategies in the field of neuroscience, it is crucial to understand fundamental baseline characteristics of locomotion in this species. Despite their relevance for medical research, little is known about the locomotion in the ovine model, and next to nothing about the three-dimensional (3D) kinematics of the hindlimb. This study is the first to perform and compare two-dimensional (2D) and 3D hindlimb kinematics of the sagittal motion during treadmill walking in the ovine model. Our results show that the most significant differences took place throughout the swing phase of the gait cycle were for the distal joints, ankle and metatarsophalangeal joint, whereas the hip and knee joints were much less affected. The results provide evidence of the inadequacy of a 2D approach to the computation of joint kinematics in clinically normal sheep during treadmill walking when the interest is centered on the hoof's joints. The findings from the present investigation are likely to be useful for an accurate, quantitative and objective assessment of functionally altered gait and its underlying neuronal mechanisms and biomechanical consequences.

Abstract
As quantum computing approaches its first commercial implementations, quantum simulation emerges as a potentially ground-breaking technology for several domains, including biology and chemistry. However, taking advantage of quantum algorithms in quantum chemistry raises a number of theoretical and practical challenges at different levels, from the conception to its actual execution. We go through such challenges in a case study of a quantum simulation for the hydrogen (H-2) and lithium hydride (LiH) molecules, at an actual commercially available quantum computer, the IBM Q. The former molecule has always been a playground for testing approximate calculation methods in quantum chemistry, while the latter is just a little bit more complex, lacking the mirror symmetry of the former. Using the variational quantum eigensolver method, we study the molecule's ground state energy versus interatomic distance, under the action of stationary electric fields (Stark effect). Additionally, we review the necessary calculations of the matrix elements of the second quantization Hamiltonian encompassing the extra terms concerning the action of electric fields, using STO-LG-type atomic orbitals to build the minimal basis sets.

Abstract
Exposure to air pollution in early years can exacerbate the risk of noncommunicable diseases throughout childhood and the entire life course. This study aimed to assess temperature, relative humidity (RH), carbon dioxide (CO2) and monoxide (CO), particulate matter (PM2.5, PM10), ultrafine particles, nitrogen dioxide (NO2), ozone (O3), formaldehyde, acetaldehyde and volatile organic compounds (VOC) levels in the two rooms where infant twins spend more time at home (30 dwellings, Northern Portugal). Findings showed that, in general, the worst indoor environmental quality (IEQ) settings were found in bedrooms. In fact, although most of the bedrooms surveyed presented adequate comfort conditions in terms of temperature and RH, several children are sleeping in a bedroom with improper ventilation and/or with a significant degree of air pollution. In particular, mean concentrations higher than recommended limits were found for CO2, PM2.5, PM10 and total VOC. Additionally, terpenes and decamethylcyclopentasiloxane were identified as main components of emissions from indoor sources. Overall, findings revealed that factors related to behaviors of the occupants, namely related to a conscientious use of cleaning products, tobacco and other consumer products (air-fresheners, incenses/candles and insecticides) and promotion of ventilation are essential for the improvement of air quality in households and for the promotion of children's health.