Abstract
Nuclear-derived morphological features and biomarkers provide relevant insights regarding the tumour microenvironment, while also allowing diagnosis and prognosis in specific cancer types. However, manually annotating nuclei from the gigapixel Haematoxylin and Eosin (H&E)-stained Whole Slide Images (WSIs) is a laborious and costly task, meaning automated algorithms for cell nuclei instance segmentation and classification could alleviate the workload of pathologists and clinical researchers and at the same time facilitate the automatic extraction of clinically interpretable features for artificial intelligence (AI) tools. But due to high intra- and inter-class variability of nuclei morphological and chromatic features, as well as H&Estains susceptibility to artefacts, state-of-the-art algorithms cannot correctly detect and classify instances with the necessary performance. In this work, we hypothesize context and attention inductive biases in artificial neural networks (ANNs) could increase the performance and generalization of algorithms for cell nuclei instance segmentation and classification. To understand the advantages, use-cases, and limitations of context and attention-based mechanisms in instance segmentation and classification, we start by reviewing works in computer vision and medical imaging. We then conduct a thorough survey on context and attention methods for cell nuclei instance segmentation and classification from H&E-stained microscopy imaging, while providing a comprehensive discussion of the challenges being tackled with context and attention. Besides, we illustrate some limitations of current approaches and present ideas for future research. As a case study, we extend both a general (Mask-RCNN) and a customized (HoVer-Net) instance segmentation and classification methods with context- and attention-based mechanisms and perform a comparative analysis on a multicentre dataset for colon nuclei identification and counting. Although pathologists rely on context at multiple levels while paying attention to specific Regions of Interest (RoIs) when analysing and annotating WSIs, our findings suggest translating that domain knowledge into algorithm design is no trivial task, but to fully exploit these mechanisms in ANNs, the scientific understanding of these methods should first be addressed.

Abstract
PurposeThe present study aims to analyse the presumed relationship between VLC use and students' grades.Design/methodology/approachThe research strategy unfolds as a case study (Yin, 1994), framed by how undergraduate students of pharmaceutical sciences used video lecture capture (VLC) and the impact of VLC on pedagogic differentiation. Looking at the course of Mechanistic Toxicology (MecTox), the objective is to describe this case of pharmaceutical sciences in depth.FindingsThe findings reveal that over 90% of students engaged with VLC videos, with the average viewing time exceeding the total available video minutes, indicating strong student engagement. The study particularly highlights VLC's positive impact on students with lower academic performance (grades D and E), suggesting that VLC can help reduce the performance gap and support a more inclusive educational environment.Research limitations/implicationsThe findings may have limited generalisability beyond the specific context and sample used. However, this study allows the research findings to be compared with previous research (Remi & atilde;o et al., 2022), contributing to the debate on how pedagogic research can promote evidence-based decisions regarding innovative strategies. The meaning of educational inclusion processes and diversity is, thus, contingent on the institutionalisation of research as a practice of teaching and learning.Practical implicationsThe results of this study thus provide interesting insights for the design of strategic action, considering the diversity of students as seen in parents' academic qualifications and students' conditions (e.g. student-workers, living away from home, holding a grant of economic and social support).Social implicationsThe implications of research findings for society bring the issue of equity in education to the fore. By addressing the diverse needs of students, HEIs can contribute to greater educational equity.Originality/valueUsing VLC as a differentiated pedagogic device might give diversity real content insofar as institutional and national policies can mitigate the possible negative effects of parents' low academic qualifications and the students' conditions of living away from their residence area and holding a grant of economic and social support.

Abstract
In many data stream applications, there is a normal concept, and the objective is to identify normal and abnormal concepts by training only with normal concept instances. This scenario is known in the literature as one-class learning (OCL) for data streams. In this OCL scenario for data streams, we highlight two main gaps: (i) lack of methods based on graph neural networks (GNNs) and (ii) lack of interpretable methods. We introduce OPENCAST (One-class graPh autoENCoder for dAta STream), a new method for data streams based on OCL and GNNs. Our method learns representations while encapsulating the instances of interest through a hypersphere. OPENCAST learns low-dimensional representations to generate interpretability in the representation learning process. OPENCAST achieved state-of-the-art results for data streams in the OCL scenario, outperforming seven other methods. Furthermore, OPENCAST learns low-dimensional representations, generating interpretability in the representation learning process and results.

Abstract

Abstract
Recent state-of-the-art forecasting methods are trained on collections of time series. These methods, often referred to as global models, can capture common patterns in different time series to improve their generalization performance. However, they require large amounts of data that might not be available. Moreover, global models may fail to capture relevant patterns unique to a particular time series. In these cases, data augmentation can be useful to increase the sample size of time series datasets. The main contribution of this work is a novel method for generating univariate time series synthetic samples. Our approach stems from the insight that the observations concerning a particular time series of interest represent only a small fraction of all observations. In this context, we frame the problem of training a forecasting model as an imbalanced learning task. Oversampling strategies are popular approaches used to handle the imbalance problem in machine learning. We use these techniques to create synthetic time series observations and improve the accuracy of forecasting models. We carried out experiments using 7 different databases that contain a total of 5502 univariate time series. We found that the proposed solution outperforms both a global and a local model, thus providing a better trade-off between these two approaches.

Abstract
Latent Dirichlet Allocation (LDA) is a fundamental method for clustering short text streams. However, when applied to large datasets, it often faces significant challenges, and its performance is typically evaluated in domain-specific datasets such as news and tweets. This study aims to fill this gap by evaluating the effectiveness of short text clustering methods in a large and diverse e-commerce dataset. We specifically investigate how well these clustering algorithms adapt to the complex dynamics and larger scale of e-commerce text streams, which differ from their usual application domains. Our analysis focuses on the impact of high homogeneity scores on the reported Normalized Mutual Information (NMI) values. We particularly examine whether these scores are inflated due to the prevalence of single-element clusters. To address potential biases in clustering evaluation, we propose using the Akaike Information Criterion (AIC) as an alternative metric to reduce the formation of single-element clusters and provide a more balanced measure of clustering performance. We present new insights for applying short text clustering methodologies in real-world situations, especially in sectors like e-commerce, where text data volumes and dynamics present unique challenges.