Abstract
Index structures were often used to optimise fetch operations to external storage devices (secondary memory). Nowadays, this also holds for increasingly large amounts of data residing in main-memory (primary memory). Within this scope, this work focuses on index structures that efficiently insert, query and delete valid-time data from very large datasets. This work performs a comparative study on the performance of the Interval B+ tree (IB+ tree) and the Improved Interval B+ tree (I2B+ tree): a variant that improves the time-efficiency of the deletion operation by reducing the number of traversed nodes to access siblings. We performed an extensive analysis of the performance of two operations: insertions and deletions, on both index structures, using multiple datasets with growing volumes of data, distinct temporal distributions and tree parameters (time-split alpha and node order). Results confirm that the I2B+ tree globally outperforms the IB+ tree, since, on average, deletion operations are 7% faster, despite insertions requiring 2% more time. Furthermore, results also allowed to determine the key factors that augment the performance difference on deletions between both trees. Copyright © 2021 by Author/s and Licensed by Veritas Publications Ltd., UK.

Abstract
iReceptor Plus will enable researchers around the world to share and analyse huge immunological distributed datasets, from multiple countries, containing sequencing data pertaining to both healthy and sick individuals. Most of the Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) data is currently stored and curated by individual labs, using a variety of tools and technologies.

Abstract
Index structures are fast-access methods. In the past, they were often used to minimise fetch operations to external storage devices (secondary memory). Nowadays, this also holds for increasingly large amounts of data residing in main-memory (primary memory). Examples of software that deals with this fact are in-memory databases and mobile device applications. Within this scope, this paper focuses on index structures to store, access and delete interval-based time-dependent (temporal) data from very large datasets, in the most efficient way. Index structures for this domain have specific characteristics, given the nature of time and the requirement to index time intervals. This work presents an open-source time-efficiency focused variant of the original Interval B+ tree. We designate this variant Improved Interval B+ tree (I2B+ tree). Our contribution adds to the performance of the delete operation by reducing the amount of traversed nodes to access siblings. We performed an extensive analysis of insert, range queries and deletion operations, using multiple datasets with growing volumes of data, distinct temporal distributions and tree parameters (time-split and node order). Results of the experiments validate the logarithmic performance of these operations and propose the best-observed tree parameter ranges.

Abstract
Delivering information timely across the logistics network is a challenge considering the diversity of entities, technologies, IT maturity and legislation. A way to overcome those challenges is to bring all the parties to a common level by providing technology able to fast and easily connect every system and a common language to allow efficient communication between logistics stakeholders. When we apply the Synchromodality and the Digital twin concepts to logistics, significant improvements can be achieved. Shippers and Integrators can act more precisely, deciding in any step of the global operation by what mode should be selected or combined and following the strict regulations and issuing the mandatory documents timely to avoid bottlenecks. This work produced one real business scenario where the 4-corner model technology-based solution enables synchromodality across the logistics network of one industry unit and its providers and the Digital twin for the process and the VGM (Verified Gross Mass) formality documents. As a solution to this scenario we propose collaboration networks between logistics stakeholders that provide interoperable, low-cost, reliable and secure data exchange, without requiring significant IT developments. To this purpose we studied and developed a demonstrator and tested our solution that consists of the adoption of the 4-corner model as described by Connecting Europe Facility (CEF) eDelivery using access points and the adoption of the standard e-Freight to exchange data over the collaboration network. The widespread use of this solution will increase global efficiency, make the inclusion of every client and provider regardless of resources available, and avoid imponderables in the logistics network. © 2020 IEEE.

Abstract
The development of a single window system for collaborative Multimodal Logistics services with offer for optimized and integrated door-to-door services is a complex endeavor. The concept was previously worked on by a set of European projects whose results were taken as best practices and lessons learned from the logistics sector. In this current paper we present a background and the major problems faced by the logistics sector and how IT can address them, and the existing expectations for collaborative real time door-to-door logistics Services. Next, we present the main results, consisting of an innovative system addressing these expectations - the Logistics Single Window. Finally we draw the conclusions from the results and present how the results innovate when compared with current state of the art. © 2017 IEEE.