2013
Autores
Guedes, N; Pinto, T; Vale, ZA; Sousa, TM; Sousa, T;
Publicação
24th International Workshop on Database and Expert Systems Applications, DEXA 2013, Prague, Czech Republic, August 26-29, 2013
Abstract
2013
Autores
Chambel, T; Bove, VM; Strover, S; Viana, P; Thomas, G;
Publicação
MM 2013 - Proceedings of the 2013 ACM Multimedia Conference
Abstract
Immersive media has the potential for strong impact on users' emotions and their sense of presence and engagement. The main objective of this workshop is to bring together researchers, students, media producers, service providers and industry players in the area of emergent immersive media. The workshop will provide a platform for a deep discussion on ongoing work, recent achievements and experiences. It is expected not only to consolidate experiences but also to identify aspects where strong collaboration among all the interested players is needed and to point towards future working directions. Copyright © 2013 ACM.
2013
Autores
Costa, PM; Pitt, J; Galvao, T; Falcao E Cunha, J;
Publicação
MobileHCI 2013 - Proceedings of the 15th International Conference on Human-Computer Interaction with Mobile Devices and Services
Abstract
In recent years, the technological developments in mobile and communication networks have paved the way for smart environments, whose final goal is to provide users with enhanced experiences. The measure of user experience satisfaction, or quality of experience, may be defined as an affective state in response to a service. Thus, an experiment was devised to explore the relationship between users' affective state and their context, for assessing quality of experience in urban public transport services. A pilot study, conducted to evaluate the feasibility and requirements of such an experiment is presented, leading to a large scale field study. © 2013 Authors.
2013
Autores
Domingues, MA; Soares, C; Jorge, AM;
Publicação
INFORMATION SYSTEMS AND E-BUSINESS MANAGEMENT
Abstract
The goal of many web portals is to select, organize and distribute content in order to satisfy its users/customers. This process is usually based on meta-data that represent and describe content. In this paper we describe a methodology and a system to monitor the quality of the meta-data used to describe content in web portals. The methodology is based on the analysis of the meta-data using statistics, visualization and data mining tools. The methodology enables the site's editor to detect and correct problems in the description of contents, thus improving the quality of the web portal and the satisfaction of its users. We also define a general architecture for a system to support the proposed methodology. We have implemented this system and tested it on a Portuguese portal for management executives. The results validate the methodology proposed.
2013
Autores
Alwen, J; Barbosa, M; Farshim, P; Gennaro, R; Gordon, SD; Tessaro, S; Wilson, DA;
Publicação
IMACC
Abstract
We investigate the relationship between Functional Encryption (FE) and Fully Homomorphic Encryption (FHE), demonstrating that, under certain assumptions, a Functional Encryption scheme supporting evaluation on two ciphertexts implies Fully Homomorphic Encryption. We first introduce the notion of Randomized Functional Encryption (RFE), a generalization of Functional Encryption dealing with randomized functionalities of interest in its own right, and show how to construct an RFE from a (standard) semantically secure FE. For this we define the notion of entropically secure FE and use it as an intermediary step in the construction. Finally we show that RFEs constructed in this way can be used to construct FHE schemes thereby establishing a relation between the FHE and FE primitives. We conclude the paper by recasting the construction of RFE schemes in the context of obfuscation. © 2013 Springer-Verlag Berlin Heidelberg.
2013
Autores
Pinho, SS; Figueiredo, J; Cabral, J; Carvalho, S; Dourado, J; Magalhaes, A; Gaertner, F; Mendonca, AM; Isaji, T; Cu, JG; Carneiro, F; Seruca, R; Taniguchi, N; Reis, CA;
Publicação
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Abstract
Background: E-cadherin is a cell-cell adhesion molecule and the dysfunction of which is a common feature of more than 70% of all invasive carcinomas, including gastric cancer. Mechanisms behind the loss of E-cadherin function in gastric carcinomas include mutations and silencing at either the DNA or RNA level. Nevertheless, in a high percentage of gastric carcinoma cases displaying E-cadherin dysfunction, the mechanism responsible for E-cadherin dysregulation is unknown. We have previously demonstrated the existence of a bi-directional cross-talk between E-cadherin and two major N-glycan processing enzymes, N-acetylglucosaminyltransferase-III or -V (GnT-III or GnT-V). Methods: In the present study, we have characterized the functional implications of the N-glycans catalyzed by GnT-III and GnT-V on the regulation of E-cadherin biological functions and in the molecular assembly and stability of adherens-junctions in a gastric cancer model. The results were validated in human gastric carcinoma samples. Results: We demonstrated that GnT-III induced a stabilizing effect on E-cadherin at the cell membrane by inducing a delay in the turnover rate of the protein, contributing for the formation of stable and functional adherens-junctions, and further preventing clathrin-dependent E-cadherin endocytosis. Conversely, GnT-V promotes the destabilization of E-cadherin, leading to its mislocalization and unstable adherens-junctions with impairment of cell-cell adhesion. Conclusions: This supports the role of GnT-III on E-cadherin-mediated tumor suppression, and GnT-V on E-cadherin-mediated tumor invasion. General significance: These results contribute to fill the gap of knowledge of those human carcinoma cases harboring E-cadherin dysfunction, opening new insights into the molecular mechanisms underlying E-cadherin regulation in gastric cancer with potential translational clinical applications.
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