Abstract
Many of nowadays organizations can be said to be knowledge-based. That is, they have relevant decision-making processes that are supported by data and data mining processes. These data may be created/collected by the organization or acquired from external sources (e.g. open data portals). In any case, the quality of the data will, ultimately, be one of the main drivers of decision quality. In this context, it is important that data-producing organizations also produce relevant meta-information characterizing the provenance of the data, its context or the representation standards used. This paper presents a framework to facilitate this process, promoting the inclusion of information concerning representation standards, provenance, trust and permissions at the data level. The main goal is to promote data usability and, consequently, its value for the organizations.

Abstract
Due to their universal accessibility, interactivity and scaling ease, Web applications relying on client-side code execution are currently the most common form of delivering applications and it is likely that they will continue to enter into less common realms such as IoT-based applications. We reason that modern Web applications should be able to exhibit advanced security protection mechanisms and review the research literature that points to useful partial solutions. Then, we propose a framework to support such characteristics and the features needed to implement them, providing a roadmap for a comprehensive solution to support Web application integrity. Copyright

Abstract
The main purpose of this paper is to help small businesses such as startups to successfully adopt and implement digital marketing as a strategy in their business plan. Given that many of these companies have a considerable number of fragile internal characteristics, such as a lack of access to financial capital while lacking also qualified human resources, they can't adopt a technology without first evaluating how it would affect them. With this in mind, this study will go through several stages of qualitative analysis to find the most relevant and important factors in the adoption of digital marketing in startups. We are looking to validate the results of each step with experts in the field; in order to do that an online focus group tool will be used so that the digital marketing specialists can propound their opinions.

Abstract

Abstract
Localization and Mapping of autonomous robots in an harsh and unstable environment such as a steep slope vineyard is a challenging research topic. Dead Reckoning systems can fail due to the harsh conditions of the terrain, and the Global Position System can be affected by noise or even be unavailable. Agriculture is moving towards precision agriculture, with advanced monitoring systems and wireless sensor networks. These systems and wireless sensors are installed in the crop field and can be considered relevant landmarks for robot localization. In this paper the distance accuracy provided by bluetooth based sensors is deeply studied and characterized. It is considered a multi antenna receiver bluetooth system and obtained the transfer functions (from Received Signal Strength Indication (RSSI) to distance estimation) for each set of antenna and sensors. The performance of this technology is compared against Time-of-flight based technologies (Pozyx). The obtained results show that the agricultural wireless sensors can be used as redundant artificial landmarks for localization purposes. Besides, the RSSI characterization allowed to improve the previous results of our Beacon Mapping Procedure (BMP) required for accurate and reliable localization systems.

Abstract
In Portugal, tetrahydrobiopterin (BH4)-responsive patients with phenylketonuria (PKU) are identified using a loading test (LT). Phenylalanine/natural protein (Phe/NP) intake is increased to elevate blood Phe prior to the LT. In a longitudinal retrospective study, the impact of Phe/NP titration post-LT in 58 patients (19.6 ± 8.2 years) with PKU during 4 study periods (SPs) was examined. In SP1 (2010-2013), patients were diet treated only; in SP2 (2014), the Phe/NP titration was followed by the LT in SP3 (2015). In SP4 (2016), patients received diet treatment only (n = 49) or BH4 + diet (n = 9). The median percentage blood Phe within the target range was higher in SP1 versus SP4 (64 [28-85] vs 45 [0-66]; P <.001). Our results suggest that transient Phe/NP titration, associated with a deliberate increase in NP, may adversely affect metabolic control. Controlled studies are necessary to examine the longer term impact of temporary increased NP with BH4 LT in non-BH4-responsive patients.