Abstract
The vast datasets produced in human genomics must be efficiently stored, transferred, and processed while prioritizing storage space and restore performance. Balancing these two properties becomes challenging when resorting to traditional data compression techniques. In fact, specialized algorithms for compressing sequencing data favor the former, while large genome repositories widely resort to generic compressors (e.g., GZIP) to benefit from the latter. Notably, human beings have approximately 99.9 percent of DNA sequence similarity, vouching for an excellent opportunity for deduplication and its assets: leveraging inter-file similarity and achieving higher read performance. However, identity-based deduplication fails to provide a satisfactory reduction in the storage requirements of genomes. In this article, we balance space savings and restore performance by proposing GenoDedup, the first method that integrates efficient similarity-based deduplication and specialized delta-encoding for genome sequencing data. Our solution currently achieves 67.8 percent of the reduction gains of SPRING (i.e., the best specialized tool in this metric) and restores data 1.62x faster than SeqDB (i.e., the fastest competitor). Additionally, GenoDedup restores data 9.96x faster than SPRING and compresses files 2.05x more than SeqDB.

Abstract
Human Activity Recognition is focused on the use of sensing technology to classify human activities and to infer human behavior. While traditional machine learning approaches use hand-crafted features to train their models, recent advancements in neural networks allow for automatic feature extraction. Auto-encoders are a type of neural network that can learn complex representations of the data and are commonly used for anomaly detection. In this work we propose a novel multi-class algorithm which consists of an ensemble of auto-encoders where each auto-encoder is associated with a unique class. We compared the proposed approach with other state-of-the-art approaches in the context of human activity recognition. Experimental results show that ensembles of auto-encoders can be efficient, robust and competitive. Moreover, this modular classifier structure allows for more flexible models. For example, the extension of the number of classes, by the inclusion of new auto-encoders, without the necessity to retrain the whole model. (c) 2021 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http:// creativecommons.org/licenses/by/4.0/).

Abstract
This paper addresses a new Mixed-model Assembly Line Sequencing Problem in the Footwear industry. This problem emerges in a large company, which benefits from advanced automated stitching systems. However, these systems need to be managed and optimised. Operators with varied abilities operate machines of various types, placed throughout the stitching lines. In different quantities, the components of the various shoe models, placed in boxes, move along the lines in either direction. The work assumes that the associated balancing problems have already been solved, thus solely concentrating on the sequencing procedures to minimise the makespan. An optimisation model is presented, but it has just been useful to structure the problems and test small instances due to the practical problems' complexity and dimension. Consequently, two methods were developed, one based on Variable Neighbourhood Descent, named VND-MSeq, and the other based on Genetic Algorithms, referred to as GA-MSeq. Computational results are included, referring to diverse instances and real large-size problems. These results allow for a comparison of the novel methods and to ascertain their effectiveness. We obtained better solutions than those available in the company.

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Abstract
The Internet of Things has revolutionized the way we can think about sales and customer relationship management strategies. In this context, a view of the world where technology is embedded in practically all objects and physical spaces will be an expectable reality. This reality opens up unprecedented opportunities with regard to the levels of customization in the sales process, whether in virtual spaces or in physical spaces. However, IoT also poses enormous challenges in the field of security and in particular in the field of user privacy. In this context, this article, after analyzing some of the main challenges for IoT in the privacy domain and what impact the IoT may have in the business domain and in particular in the subdomains of sales and advertising, presents a conceptual model to support customer empowerment while citizen with regard to the definition and management of privacy policies concerns a context that may go beyond the boundaries of citizenship and be applied in scenarios without borders, whenever there is the possibility of defining policies and legislation above Country. © 2021, The Author(s), under exclusive license to Springer Nature Switzerland AG.