Abstract
Immunohistochemistry (IHC) is crucial for the clinical categorisation of breast cancer cases. Deep generative models may offer a cost-effective alternative by virtually generating IHC images from hematoxylin and eosin samples. This review explores the state-of-the-art in virtual staining for breast cancer biomarkers (HER2, PgR, ER and Ki-67) and benchmarks several models on public datasets. It serves as a resource for researchers and clinicians interested in applying or developing virtual staining techniques.

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Deep learning models have excelled in computer vision tasks in the past decade, but their lack of transparency raises ethical and legal concerns, especially in high-stakes areas such as surveillance and law enforcement. As such, regulations like the European Union's General Data Protection Regulation are now demanding interpretable Artificial Intelligence systems. This paper focuses on automatic face recognition, where existing systems lack interpretability and research into explainable alternatives is limited. To address this gap, we propose two interpretable facial verification models based on Siamese Networks that match and compare semantically-aligned local regions in the images. Experiments show these models rival and even outperform traditional baselines while offering clearer, more accountable explanations, advancing ethical and legally compliant facial recognition.

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