Abstract
Assembly lines are at the core of many manufacturing systems, and planning for a well-balanced flow is key to ensure long-term efficiency. However, in flexible configurations such as Multi-Manned Assembly Lines (MMAL), the balancing problem also becomes more challenging. Due to the increased relevance of these assembly lines, this work aims to investigate the MMAL balancing problem, to contribute for a more effective decision-making process. Therefore, a new approach is proposed based on Deep Reinforcement Learning (DRL) embedded in a Digital Twin architecture. The proposed approach provides a close-to-reality training environment for the agent, using Discrete Event Simulation to simulate the production system dynamics. This methodology was tested on a real-world instance with preliminary results showing that similar solutions to the ones obtained using optimization-based strategies are achieved. This research provides evidence of success in terms of dynamic resource assignment to tasks and workers as a basis for future developments.

Abstract

Abstract
To design and deploy their supply chains, companies must naturally take quite different decisions, some being strategic or tactical, and others of an operational nature. This work resulted in a decision support system for optimising a biomass supply chain in Portugal, allowing a more efficient operations management, and enhancing the design process. Uncertainty and variability in the biomass supply chain is a critical issue that needs to be considered in the production planning of bioenergy plants. A simulation/optimisation framework was developed to support decision-making, by combining plans generated by a resource allocation optimisation model with the simulation of disruptive wildfire scenarios in the forest biomass supply chain. Different scenarios have been generated to address uncertainty and variability in the quantity and quality of raw materials in the different supply nodes. Computational results show that this simulation/optimisation approach can have a significant impact in the operations efficiency, particularly when disruptions occur closer to the end of the planning horizon. The approach seems to be easily scalable and easy to extend to other sectors.

Abstract
The rapid advancement of warehouse automation has increased the need for intelligent intralogistics solutions that enhance material handling efficiency and optimize space utilization. This research presents a simulation-based methodology that integrates Autonomous Mobile Robots (AMRs) with container loading optimization in a unified decision-support framework that dynamically synchronizes AMR routing with optimized truckload configurations, a feature not commonly addressed jointly in existing literature to improve warehouse operations. By leveraging a hybrid approach combining discrete event and agent-based simulation in FlexSim, the study evaluates the impact of AMR fleet size, routing strategies, and truckload configurations on overall logistics performance. A proof-of-concept industrial case study illustrates how different scenarios influence key performance metrics, such as total operation time and resource utilization. The findings demonstrate that synchronized AMR deployment and optimized container loading strategies contribute to increased throughput, reduced handling time, and enhanced logistics unit utilization. This work provides a framework for dynamic logistics planning, offering valuable insights for companies seeking to enhance warehouse efficiency and sustainability through simulation-driven decision support. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2026.

Abstract
The adoption of Autonomous Mobile Robots (AMRs) has emerged as a promising solution to enhance efficiency and reduce operational costs for industrial companies. Given the significant cost of AMRs, it is crucial to determine the optimal number and characteristics before making significant investments. This study proposes a decision-support framework based on simulation to assess the impact of integrating AMR robots in a complex distribution center. Additionally, this framework aids decision-makers in determining the optimal fleet size of AMR robots and corresponding charging stations. A simulation model was developed using data from a leading retail company, focusing on pallet movement within the facility, comparing scenarios combining AMRs with other intralogistics implementations. This methodology incorporates uncertainty, variability (statistical distributions to create transportation orders, acceleration, demand and offer fluctuations) and implements fleet management, transportation capacity, demand matching, and resource utilization according to real case scenarios. The proposed model replicates accurate robot coordination and actual deployment environments, ensuring that the tested scenarios approximate the real-world conditions as much as possible. Preliminary findings show results supporting the decision-making for a fleet size to meet weekly production targets, optimize robot utilization, and coordinate charging instances to prevent production stops. Conclusions suggest that the proposed simulation approach is an effective tool for planning and implementing logistics solutions, enabling users to make informed decisions before investing. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2026.