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Publicações

Publicações por João Manuel Pedrosa

2019

Velocities of Naturally Occurring Myocardial Shear Waves Increase With Age and in Cardiac Amyloidosis

Autores
Petrescu, A; Santos, P; Orlowska, M; Pedrosa, J; Bézy, S; Chakraborty, B; Cvijic, M; Dobrovie, M; Delforge, M; D’hooge, J; Voigt, J;

Publicação
JACC: Cardiovascular Imaging

Abstract

2019

Deep Learning for Segmentation using an Open Large-Scale Dataset in 2D Echocardiography

Autores
Leclerc, S; Smistad, E; Pedrosa, J; Ostvik, A; Cervenansky, F; Espinosa, F; Espeland, T; Berg, EAR; Jodoin, P; Grenier, T; Lartizien, C; Drhooge, J; Lovstakken, L; Bernard, O;

Publicação
IEEE Transactions on Medical Imaging

Abstract

2018

Ventricular mechanics in adolescent and adult patients with a Fontan circulation: Relation to geometry and wall stress

Autores
Rösner, A; Khalapyan, T; Pedrosa, J; Dalen, H; McElhinney, DB; Friedberg, MK; Lui, GK;

Publicação
Echocardiography

Abstract

2018

Fully Automatic Assessment of Mitral Valve Morphology from 3D Transthoracic Echocardiography

Autores
Pedrosa, J; Queiros, S; Vilaca, J; Badano, L; D'hooge, J;

Publicação
2018 IEEE International Ultrasonics Symposium (IUS)

Abstract

2018

Natural shear wave imaging in the human heart: normal values, feasibility and reproducibility

Autores
Santos, P; Petrescu, A; Pedrosa, J; Orlowska, M; Komini, V; Voigt, J; D'hooge, J;

Publicação
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control

Abstract

2019

Non-invasive myocardial performance mapping using 3D echocardiographic stress-strain loops

Autores
Pedrosa, J; Duchenne, J; Queiros, S; Degtiarova, G; Gheysens, O; Claus, P; Voigt, JU; D'hooge, J;

Publicação
PHYSICS IN MEDICINE AND BIOLOGY

Abstract
Regional contribution to left ventricular (LV) ejection is of much clinical importance but its assessment is notably challenging. While deformation imaging is often used, this does not take into account loading conditions. Recently, a method for intraventricular pressure estimation was proposed, thus allowing for loading conditions to be taken into account in a non-invasive way. In this work, a method for 3D automatic myocardial performance mapping in echocardiography is proposed by performing 3D myocardial segmentation and tracking, thus giving access to local geometry and strain. This is then used to assess local LV stress-strain relationships which can be seen as a measure of local myocardial work. The proposed method was validated against F-18-fluorodeoxyglucose positron emission tomography, the reference method to clinically assess local metabolism. Averaged over all patients, the mean correlation between FDG-PET and the proposed method was 0.67 +/- 0.18. In conclusion, stress-strain loops were, for the first time, estimated from 3D echocardiography and correlated to the clinical gold standard for local metabolism, showing the future potential of real-time 3D echocardiography ( RT3DE) for the assessment of local metabolic activity of the heart.