Abstract
An increasing area of study for economists and sociologists is the varying organizational structures between business networks. The use of network science makes it possible to identify the determinants of the performance of these business networks. In this work we look for the determinants of inter-firm performance. On one hand, a new method of supervised clustering with attributed networks is proposed, SUWAN, with the aim at obtaining class-uniform clusters of the turnover, while minimizing the number of clusters. This method deals with representative-based supervised clustering, where a set of initial representatives is randomly chosen. One of the innovative aspects of SUWAN is that we use a supervised clustering algorithm to attributed networks that can be accomplished through a combination of weights between the matrix of distances of nodes and their attributes when defining the clusters. As a benchmark, we use Subgroup Discovery on attributed network data. Subgroup Discovery focuses on detecting subgroups described by specific patterns that are interesting with respect to some target concept and a set of explaining features. On the other hand, in order to analyze the impact of the network's topology on the group's performance, some network topology measures, and the group total turnover were exploited. The proposed methodologies are applied to an inter-organizational network, the EuroGroups Register, a central register that contains statistical information on business networks from European countries.

Abstract
Sponsored advertising on search engines is one of the fastest growing online advertising marketplaces. The space available for paid ads, or positions, is sold using auctions and payment is calculated considering the number of clicks each position receives. Two mechanisms are generally used in position auctions: Generalized Second Price (GSP) (e.g. Google, Yahoo!) and Vickrey-Clarke-Groves (VCG) (e.g. Facebook). To understand which mechanism guarantees the highest payoff to market players (search engines and advertisers), a multi-agent simulation is developed in Netlogo. Using the generated data, a supervised learning-based analysis on search engines and bidders' payoffs is made using linear regression models and regression trees. Results suggest that the average payoff for auctioneers (the search engines) and bidders (the advertisers), the price for each position, and first bidder's payment, are significantly different in the GSP and VCG mechanisms. We also found the mechanism that generates the highest payoff for the search engine is the VCG, while for the bidders it is the GSP.

Abstract
Bin picking is a challenging problem that involves using a robotic manipulator to remove, one-by-one, a set of objects randomly stacked in a container. When the objects are prone to entanglement, having an estimation of their pose and shape is highly valuable for more reliable grasp and motion planning. This paper focuses on modeling entangled tubes with varying degrees of curvature. An unconventional machine learning technique, Inductive Logic Programming (ILP), is used to construct sets of rules (theories) capable of modeling multiple tubes when given the cylinders that constitute them. Datasets of entangled tubes are created via simulation in Gazebo. Experiments using Aleph and SWI-Prolog illustrate how ILP can build explainable theories with a high performance, using a relatively small dataset and low amount of time for training. Therefore, this work serves as a proof-of-concept that ILP is a valuable method to acquire knowledge and validate heuristics for pose and shape estimation in complex bin picking scenarios.

Abstract

Abstract
This article reports on the development of a Web platform for the study of Adverse Drug Events (ADEs). The platform is able to import ADE episodes from official Web sites, like OpenFDA, analyse the chemistry of the drugs involved, together with patient data, and produce a potential explanation based on the drugs interactions. Each study uses chemical knowledge to enrich the information on the molecules involved in the episodes. Data Mining is then used to construct models that can help in the explanation of the ADE occurrence and to predict future events. This paper reports on the Web portal developed and the Data Mining experiments conducted to evaluate the quality, and potential explanations of the forecasted adverse reactions, using real reports of drug administration and the subsequent adverse events. The results showed that it was possible to predict the outcomes of ADEs based on the structure of the molecules of the drugs involved and the data collected from real reports of drug administration up to an accuracy of 79%, while also predicting, with high accuracy, the severity of events where the outcome is the death of the patient (with a precision of 98.9%). The platform provides a less expensive and more accurate way of predicting adverse drug reactions compared to traditional methods. This study highlights the importance of understanding drug interactions at a molecular level and the usefulness of utilising Data Mining techniques in predicting ADEs.

Abstract
The oral microbiota is a highly complex and diversified part of the human microbiome. Being located at the interface between the human body and the exterior environment, this microbiota can deepen our understanding of the environmental impacts on the global status of human health. This research topic has been well addressed in Westernized populations, but these populations only represent a fraction of human diversity. Papua New Guinea hosts very diverse environments and one of the most unique human biological diversities worldwide. In this study we performed the first known characterization of the oral microbiome in 85 Papua New Guinean individuals living in different environments, using a qualitative and quantitative approach. We found a significant geographical structure of the Papua New Guineans oral microbiome, especially in the groups most isolated from urban spaces. In comparison to other global populations, two bacterial genera related to iron absorption were significantly more abundant in Papua New Guineans and Aboriginal Australians, which suggests a shared oral microbiome signature. Further studies will be needed to confirm and explore this possible regional-specific oral microbiome profile.