2023
Autores
Duarte, M; Pereira-Rodrigues, P; Ferreira-Santos, D;
Publicação
Abstract Clinical digital tools are an up-and-coming new technology that can be used in the screening or diagnosis of obstructive sleep apnea (OSA) patients, notwithstanding the crucial role of polysomnography (PSG) – the gold standard. The aim of our study was to identify, gather, and analyze existing digital tools and smartphone-based health platforms that are being used for this disease’s screening or diagnosis in the adult population. We performed a comprehensive literature search in MEDLINE, Scopus, and Web of Science databases for studies evaluating the validity of digital tools in OSA screening or diagnosis until November 2022. The risk of bias was assessed using JBI Critical Appraisal Tool for Diagnostic Test Accuracy Studies. Sensitivity, specificity, and area under the receiver-operating curve (AUC) were used as discrimination measures. We retrieved 1714 articles, 41 of which were included. We found 7 smartphone-based tools, 10 wearables, 11 bed/mattress sensors, 5 nasal airflow devices, and 8 other sensors that did not fit the previous categories. Only 8 (20%) studies performed external validation of their developed tool. Of those, the highest reported values for AUC, sensitivity, and specificity were 0.99, 96%, and 92%, respectively, for a clinical cutoff of apnea-hypopnea index (AHI) = 30 and correspond to a non-contact audio recorder that records sleep sounds, which are then analyzed by a deep learning technique that automatically detects sleep apnea events, calculates the AHI, and identifies OSA. Looking at the studies that only internally validated their models, the work that reported the highest accuracy measures showed AUC, sensitivity, and specificity values of 1.00, 100%, and 96%, respectively, for a clinical cutoff AHI = 30. It uses the Sonomat – a foam mattress that, aside from recording breath sounds, has pressure sensors that generate voltage when deformed, thus detecting respiratory movements, and using it to classify OSA events. These clinical tools presented promising results, showing high discrimination measures (best results reaching AUC > 0.99). However, there is still a need for quality studies, comparing the developed tools with the gold standard and validating them in external populations and other environments before they can be used in a clinical setting. This systematic review was registered in PROSPERO under reference CRD42023387748.
2023
Autores
Maksimenko, J; Rodrigues, PP; Nakazawa-Miklasevica, M; Pinto, D; Miklasevics, E; Trofimovics, G; Gardovskis, J; Cardoso, F; Cardoso, MJ;
Publicação
JMIR FORMATIVE RESEARCH
Abstract
2023
Autores
Portela, D; Amaral, R; Rodrigues, PP; Freitas, A; Costa, E; Fonseca, JA; Sousa Pinto, B;
Publicação
HEALTH INFORMATION MANAGEMENT JOURNAL
Abstract
Background Quantifying and dealing with lack of consistency in administrative databases (namely, under-coding) requires tracking patients longitudinally without compromising anonymity, which is often a challenging task. Objective This study aimed to (i) assess and compare different hierarchical clustering methods on the identification of individual patients in an administrative database that does not easily allow tracking of episodes from the same patient; (ii) quantify the frequency of potential under-coding; and (iii) identify factors associated with such phenomena. Method We analysed the Portuguese National Hospital Morbidity Dataset, an administrative database registering all hospitalisations occurring in Mainland Portugal between 2011-2015. We applied different approaches of hierarchical clustering methods (either isolated or combined with partitional clustering methods), to identify potential individual patients based on demographic variables and comorbidities. Diagnoses codes were grouped into the Charlson an Elixhauser comorbidity defined groups. The algorithm displaying the best performance was used to quantify potential under-coding. A generalised mixed model (GML) of binomial regression was applied to assess factors associated with such potential under-coding. Results We observed that the hierarchical cluster analysis (HCA) + k-means clustering method with comorbidities grouped according to the Charlson defined groups was the algorithm displaying the best performance (with a Rand Index of 0.99997). We identified potential under-coding in all Charlson comorbidity groups, ranging from 3.5% (overall diabetes) to 27.7% (asthma). Overall, being male, having medical admission, dying during hospitalisation or being admitted at more specific and complex hospitals were associated with increased odds of potential under-coding. Discussion We assessed several approaches to identify individual patients in an administrative database and, subsequently, by applying HCA + k-means algorithm, we tracked coding inconsistency and potentially improved data quality. We reported consistent potential under-coding in all defined groups of comorbidities and potential factors associated with such lack of completeness. Conclusion Our proposed methodological framework could both enhance data quality and act as a reference for other studies relying on databases with similar problems.
2023
Autores
Portela, D; Rodrigues, PP; Freitas, A; Costa, E; Bousquet, J; Fonseca, JA; Pinto, BS;
Publicação
JOURNAL OF ASTHMA
Abstract
Background: Most previous studies assessing multimorbidity in asthma assessed the frequency of individual comorbid diseases. Objective: We aimed to assess the frequency and clinical and economic impact of co-occurring groups of comorbidities (comorbidity patterns using the Charlson Comorbidity Index) on asthma hospitalizations. Methods: We assessed the dataset containing a registration of all Portuguese hospitalizations between 2011-2015. We applied three different approaches (regression models, association rule mining, and decision trees) to assess both the frequency and impact of comorbidities patterns in the length-of-stay, in-hospital mortality and hospital charges. For each approach, separate analyses were performed for episodes with asthma as main and as secondary diagnosis. Separate analyses were performed by participants' age group. Results: We assessed 198340 hospitalizations in patients >18 years old. Both in hospitalizations with asthma as main or secondary diagnosis, combinations of diseases involving cancer, metastasis, cerebrovascular disease, hemiplegia/paraplegia, and liver disease displayed a relevant clinical and economic burden. In hospitalizations having asthma as a secondary diagnosis, we identified several comorbidity patterns involving asthma and associated with increased length-of-stay (average impact of 1.3 [95%CI=0.6-2.0]-3.2 [95%CI=1.8-4.6] additional days), in-hospital mortality (OR range=1.4 [95%CI=1.0-2.0]-7.9 [95%CI=2.6-23.5]) and hospital charges (average additional charges of 351.0 [95%CI=219.1-482.8] to 1470.8 [95%CI=1004.6-1937.0]) Euro compared with hospitalizations without any registered Charlson comorbidity). Consistent results were observed with association rules mining and decision tree approaches. Conclusions: Our findings highlight the importance not only of a complete assessment of patients with asthma, but also of considering the presence of asthma in patients admitted by other diseases, as it may have a relevant impact on clinical and health services outcomes.
2023
Autores
Correia, A; Guimaraes, D; Paredes, H; Fonseca, B; Paulino, D; Trigo, L; Brazdil, P; Schneider, D; Grover, A; Jameel, S;
Publicação
IEEE TRANSACTIONS ON HUMAN-MACHINE SYSTEMS
Abstract
Visualizing and examining the intellectual landscape and evolution of scientific communities to support collaboration is crucial for multiple research purposes. In some cases, measuring similarities and matching patterns between research publication document sets can help to identify people with similar interests for building research collaboration networks and university-industry linkages. The premise of this work is assessing feasibility for resolving ambiguous cases in similarity detection to determine authorship with natural language processing (NLP) techniques so that crowdsourcing is applied only in instances that require human judgment. Using an NLP-crowdsourcing convergence strategy, we can reduce the costs of microtask crowdsourcing while saving time and maintaining disambiguation accuracy over large datasets. This article contributes a next-gen crowd-artificial intelligence framework that used an ensemble of term frequency-inverse document frequency and bidirectional encoder representation from transformers to obtain similarity rankings for pairs of scientific documents. A sequence of content-based similarity tasks was created using a crowd-powered interface for solving disambiguation problems. Our experimental results suggest that an adaptive NLP-crowdsourcing hybrid framework has advantages for inter-researcher similarity detection tasks where fully automatic algorithms provide unsatisfactory results, with the goal of helping researchers discover potential collaborators using data-driven approaches.
2023
Autores
Costa, C; Ferreira, CA;
Publicação
Intelligent Data Engineering and Automated Learning - IDEAL 2023 - 24th International Conference, Évora, Portugal, November 22-24, 2023, Proceedings
Abstract
Paint bases are the essence of the color palette, allowing for the creation of a wide range of tones by combining them in different proportions. In this paper, an Artificial Neural Network is developed incorporating a pre-trained Decoder to predict the proportion of each paint base in an ink mixture in order to achieve the desired color. Color coordinates in the CIELAB space and the final finish are considered as input parameters. The proposed model is compared with commonly used models such as Linear Regression, Random Forest and Artificial Neural Network. It is important to note that the Artificial Neural Network was implemented with the same architecture as the proposed model but without incorporating the pre-trained Decoder. Experimental results demonstrate that the Artificial Neural Network with a pre-trained Decoder consistently outperforms the other models in predicting the proportions of paint bases for color tuning. This model exhibits lower Mean Absolute Error and Root Mean Square Error values across multiple objectives, indicating its superior accuracy in capturing the complexities of color relationships. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2023.
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