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The Portuguese governmental network comprising all the 776 ministers and junior ministers who were part of the 19 governments between the year 1976 and 2013 is presented and analyzed. The data contain information on connections concerning business and other types of organizations and, to our knowledge, there is no such extensive research in previous literature. Upon the presentation of the data, a social network analysis considering the temporal dimension is performed at three levels of granularity: network-level, subnetwork-level (political groups) and node-level. A discussion based on the results is presented. We conclude that although it fits two of the four preconditions of a small-world model, the Portuguese governmental network is not a small-world network, although presenting an evolution pointing toward becoming one. Also, we use a resilience test to study the evolution of the robustness of the Portuguese governmental network, pinpointing the moment when a set of members became structurally important.

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Aims: Cardiovascular (CV) events are the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD), including those patients on peritoneal dialysis (PD). Fibroblast growth factor 23 (FGF23) has been associated with left ventricular hypertrophy (LVH) and mortality in patients with CKD. However, the role of FGF23 in uremic vasculopathy remains unclear. In this study, we aimed to assess the relationship between FGF23 and LVH, endothelial dysfunction, vascular calcification, and arterial stiffness in 48 stable PD patients. Methods: Left ventricular mass index (LVMI) was assessed using 2-D echocardiography. Intact FGF23 blood levels were evaluated using an ELISA kit (Immutopics, Inc., San Clemente, CA, USA). Reactive hyperemia index (RHI) is a surrogate marker of endothelial dysfunction and the augmentation index (AI) is a surrogate marker of arterial stiffness. Both were assessed using peripheral arterial tonometry (EndoPAT 2000). Vascular calcification (VC) was assessed using the Adragao score. Results: In unadjusted analysis; FGF23 was positively correlated with serum Pi (r = 0.487, p < 0.001), serum urea (r = 0.351, p = 0.015), serum creatinine (r = 0.535, p < 0.001), dialysis vintage (r = 0.309, p = 0.033), and LVMI (r = 0.369, p = 0.027) and was negatively correlated with age (r = -0.343, p = 0.017), residual renal function (r = -0.359, p < 0.012), and AI (r = -0.304, p = 0.038). In multivariate adjusted analysis, FGF23 was associated with LVMI (beta = 0.298, p = 0.041), serum Pi (beta = 0.345, p = 0.018), and age (beta = -0.372, p = 0.007) independent of dialysis vintage, gender, residual renal function (RRF), albumin, C-reactive protein and systolic blood pressure. There were no associations found between FGF23 and RHI, AI, or VC in multivariable-adjusted models. Conclusions: Our results show that FGF23 is associated with LVH but not with endothelial dysfunction, arterial stiffness, or vascular calcification in PD patients.

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Gathering knowledge about food and nutritional habits of a population is of the utmost importance since dietary intervention positively impacts health outcomes across the life span. With this transversal epidemiologic study representative of the adult Portuguese population (data from SPCNA), we tried to know the nutritional intake pattern (energy and macronutrients) of the Portuguese population. In an domiciliary individualized interview sociodemographic data were registered and food intake was evaluated by the 24-hour recall method. Portuguese energy intake, is on average, 2056 kcal/day, distributed by 19.1% of protein, 45.8% of carbohydrates and 31.3% of total fat, and 3.8% of ethanol. These data will be important to Portuguese public health interventions. © 2016 The Authors

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