Abstract
The combination of information obtained from data mining technique from physicochemical and organoleptic data analysis allowed similarities between the wines of the nine sub-regions in the Demarcated Region of Vinho Verde. Through clustering techniques, four clusters were identified, each characterized by its centroid. The measure of information gain, together with supervised rule-based learning, was used to find the differentiating characteristics. This study allowed the interconnection of the characteristics of the wines of these sub-regions, which can improve the decision making on the profiles of these same wines.

Abstract
Augmented Reality (AR) is no longer just a gimmick. 50 years after the development of the first head-mounted display, and approaching the 20th anniversary of the first conference dedicated to AR, it is time for a new review on the theme. As such, we present a bibliometric analysis of scientific literature since 1997, using as database the Web of Science. This allowed identifying the most relevant authors, their distribution by subjects, the evolution of publishing by year and the most frequent publications.

Abstract
The aim of this research is to analyze the correlates of adults' participation in sport and frequency of sport. A hurdle model approach comprising a binary choice regression to model participation in sport and a count model to address frequency of sport was applied to analyze the data obtained from 516 personal interviews in a Portuguese city. Participation in sport and frequent sport are associated with men, younger people, not married and without children under 2 years, nonsmokers and regular drinkers and with good perceived health. However, participation in sport and frequency of sport participation are associated with different levels of perception of the benefits of sport activity. Whereas awareness of the health and enjoyment benefits fosters participation, fitness, socializing and appearance might increase the frequency of sport. Sport communication strategies might play a prominent role in persuading potential participants of the benefits of sport activity and frequency.

Abstract
Cancer genome projects are characterizing the genome, epigenome and transcriptome of a large number of samples using the latest high-throughput sequencing assays. The generated data sets pose several challenges for traditional statistical and machine learning methods. In this work we are interested in the task of deriving the most informative genes from a cancer gene expression data set. For that goal we built denoising autoencoders (DAE) and stacked denoising autoencoders and we studied the influence of the input nodes on the final representation of the DAE. We have also compared these deep learning approaches with other existing approaches. Our study is divided into two main tasks. First, we built and compared the performance of several feature extraction methods as well as data sampling methods using classifiers that were able to distinguish the samples of thyroid cancer patients from samples of healthy persons. In the second task, we have investigated the possibility of building comprehensible descriptions of gene expression data by using Denoising Autoencoders and Stacked Denoising Autoencoders as feature extraction methods. After extracting information related to the description built by the network, namely the connection weights, we devised post-processing techniques to extract comprehensible and biologically meaningful descriptions out of the constructed models. We have been able to build high accuracy models to discriminate thyroid cancer from healthy patients but the extraction of comprehensible models is still very limited.

Abstract

Abstract
Recent advances in sequencing allow the study of all identified human genes (22,000 protein encoding genes), which have differential expression between tissues. However, current knowledge on gene interactions lags behind, especially when one of the elements encodes a mitochondrial protein (1500). Mitochondrial proteins are encoded either by mitochondrial DNA (mtDNA; 13 proteins) or by nuclear DNA (nDNA; the remaining), which implies a coordinated communication between the two genomes. Since mitochondria coordinate several life-critical cellular activities, namely energy production and cell death, deregulation of this communication is implicated in many complex diseases such as neurodegenerative diseases, cancer and diabetes. Thus, this work aimed to identify high co-expression groups between mitochondrial genes-all genes, and associated protein networks in several human tissues (Genotype-Tissue Expression database). We developed a pipeline and a web tree viewer that is available at GitHub (https://github.com/Pereira-lab/CoExpression). Biologically, we confirmed the existence of highly correlated pairs of mitochondrial-all protein encoding genes, which act in pathways of functional importance such as energy production and metabolite synthesis, especially in brain tissues. The strongest correlation between mtDNA genes are with genes encoded by this genome, showing that correlation among genes encoded by the same genome is more efficient.