Abstract
The Electroencephalogram (EEG) is a medical tool that captures, in a non-invasive way, electrical signals from the brain activities performed by neurons. EEG signals have been the target of study as a biomarker of Parkinsons disease (PD), where several methods of analysis are applied. The present work aims to evaluate features extracted from EEG signals, through methodologies such as HOS, Haralick descriptors, and Fractal Features, as new biomarkers for PD identification. Data from 50 individuals, available at the Open Neuro repository, who underwent an attentional cognitive task were analyzed. RF and SVM algorithms were employed for the classification of the extracted features. The best accuracy achieved was 79.49% in differentiating between Parkinsons subjects and control subjects using Haralick descriptors and RF classifier, suggesting that these features can identify activations in brain areas caused by dopaminergic medication.

Abstract
The notable expansion of technologies related to automated processes has been observed in recent years, largely driven by the significant advantages they provide across diverse industries. Concurrently, there has been a rise in simulation technologies aimed at replicating these complex systems. Nevertheless, in order to fully leverage the potential of these technologies, it is crucial to ensure the highest possible resemblance of simulations to real-world scenarios. In brief, this work consists of the development of a data acquisition and processing pipeline allowing a posterior search for the optimal physical parameters in MuJoCo simulator to obtain a more accurate simulation of a dexterous robotic hand. In the end, a Random Search optimization algorithm was used to validate this same pipeline.

Abstract

Abstract
Background/Objectives: Obstructive sleep apnea (OSA) classification relies on polysomnography (PSG) results. Current guidelines recommend the development of clinical prediction algorithms in screening prior to PSG. A recent intuitive and user-friendly tool (OSABayes), based on a Bayesian network model using six clinical variables, has been proposed to quantify the probability of OSA. Our aims are (1) to validate OSABayes prospectively, (2) to build a smartphone app based on the proposed model, and (3) to evaluate app usability. Methods: We prospectively included adult patients suspected of OSA, without suspicion of other sleep disorders, who underwent level I or III diagnostic PSG. Apnea-hypopnea index (AHI) and OSABayes probabilities were obtained and compared using the area under the ROC curve (AUC [95%CI]) for OSA diagnosis (AHI >= 5/h) and higher severity levels (AHI >= 15/h) prediction. We built the OSABayes app on 'App Inventor 2', and the usability was assessed with a cognitive walkthrough method and a general evaluation. Results: 216 subjects were included in the validation cohort, performing PSG levels I (34%) and III (66%). OSABayes presented an AUC of 83.6% [77.3-90.0%] for OSA diagnosis and 76.3% [69.9-82.7%] for moderate/severe OSA prediction, showing good response for both types of PSG. The OSABayes smartphone application allows one to calculate the probability of having OSA and consult information about OSA and the tool. In the usability evaluation, 96% of the proposed tasks were carried out. Conclusions: These results show the good discrimination power of OSABayes and validate its applicability in identifying patients with a high pre-test probability of OSA. The tool is available as an online form and as a smartphone app, allowing a quick and accessible calculation of OSA probability.

Abstract

Abstract

As climate change drives increasingly severe heatwaves, the strain on public health systems continues to grow, particularly for vulnerable populations. Our work argues for the integration of digital health technologies into heatwave action plans, drawing lessons from the COVID-19 pandemic's success in deploying such tools. It explores the potential of digital communication strategies, telemedicine, and data-driven simulations to enhance public awareness, maintain healthcare accessibility, and improve real-time crisis responses. Despite their effectiveness, digital solutions remain underutilized in existing European heat-health action plans. We emphasize the need for a proactive, systems-based approach to optimize heatwave management and ensure equitable healthcare access, particularly for at-risk communities. Integrating digital health innovations can transform heatwave response strategies, making them more flexible, efficient, and capable of saving lives.