Abstract
Nowadays, breast cancer has become the most common cancer amongst females. As long as breast is assumed to be a feminine symbol, any imposed deformation of surgical procedures can affect the patients' quality of life. However, using a planning tool which is based on parametric modeling, not only improves surgeons' skills in order to perform surgeries with better cosmetic outcomes, but also increases the interaction between surgeons and patients during the decision for necessary procedures. In the current research, a methodology of parametric modeling, called Free-Form Deformation (FFD) is studied. Finally, confirmed by a quantitative analysis, we proposed two simplified versions of FFD methodology to increase model similarity to input data and decrease required fitting time.

Abstract
In classification, when there is a disproportion in the number of observations in each class, the data is said to be class imbalance. Class imbalance is pervasive in real world applications of data classification and has been the focus of much research. The minority class contributes too little to the decision boundary because the learning process learns from each observation in isolation. In this paper, we discuss the application of learning pairwise rankers as a solution to class imbalance. We compare ranking models to alternatives from the literature.

Abstract
Background and objective: Cosmetic outcome of breast cancer conservative treatment (BCCT) remains without a standard evaluation method. Subjective methods, in spite of their low reproducibility, continue to be the most frequently used. Objective methods, although more reproducible, seem unable to translate all the subtleties involved in cosmetic outcome. The breast cancer conservative treatment cosmetic results (BCCT. core) software was developed in 2007 to try to overcome these pitfalls. The software is a semi-automatic objective tool that evaluates asymmetry, color differences and scar visibility using patient's digital pictures. The purpose of this work is to review the use of the BCCT. core software since its availability in 2007 and to put forward future developments. Methods: All the online requests for BCCT. core use were registered from June 2007 to December 2014. For each request the department, city and country as well as user intention (clinical use/research or both) were questioned. A literature search was performed in Medline, Google Scholar and ISI Web of Knowledge for all publications using and citing "BCCT.core". Results: During this period 102 centers have requested the software essentially for clinical use. The BCCT. core software was used in 19 full published papers and in 29 conference abstracts. Conclusions: The BCCT. core is a user friendly semi-automatic method for the objective evaluation of BCCT. The number of online requests and publications have been steadily increasing turning this computer program into the most frequently used tool for the objective cosmetic evaluation of BCCT.

Abstract
Patient-specific surgical predictions of Breast Conserving Therapy, through mechano-biological simulations, could inform the shared decision making process between clinicians and patients by enabling the impact of different surgical options to be visualised. We present an overview of our processing workflow that integrates MR images and three dimensional optical surface scans into a personalised model. Utilising an interactively generated surgical plan, a multi-scale open source finite element solver is employed to simulate breast deformity based on interrelated physiological and biomechanical processes that occur post surgery. Our outcome predictions, based on the pre-surgical imaging, were validated by comparing the simulated outcome with follow-up surface scans of four patients acquired 6 to 12 months post-surgery. A mean absolute surface distance of 3.3mm between the follow-up scan and the simulation was obtained.

Abstract
Motion is a fundamental cue for scene analysis and human activity understanding in videos. It can be encoded in trajectories for tracking objects and for action recognition, or in form of flow to address behavior analysis in crowded scenes. Each approach can only be applied on limited scenarios. We propose a motion-based system that represents the spatial and temporal features of the flow in terms of I ong-range trajectories. The novelty resides on the system formulation, its generic approach to handle scene variability and motion variations, motion integration from local and global representations, and the resulting long-range trajectories that overcome trajectory-based approach problems. We report the results and conclusions that state its pertinence on different scenarios, comparing and correlating the extracted trajectories of individual pedestrians, manually annotated. We also propose an evaluation framework and stress the diverse system characteristics that can be used for human activity tasks, namely on motion segmentation.

Abstract
Iris liveness detection methods have been developed to overcome the vulnerability of iris biometric systems to spoofing attacks. In the literature, it is typically assumed that a known attack modality will be perpetrated. Then liveness models are designed using labelled samples from both real/live and fake/spoof distributions, the latter derived from the assumed attack modality. In this work it is argued that a comprehensive modelling of the spoof samples is not possible in a real-world scenario where the attack modality cannot be known with a high degree of certainty. In fact making this assumption will render the liveness detection system more vulnerable to attacks that were not included in the original training. To provide a more realistic evaluation, this work proposes: a) testing the binary models with unknown spoof samples that were not present in the training step; b) the use of a single-class classification designing the classifier by modelling only the distribution of live samples. The results obtained support the assertion that many evaluation methods from the literature are misleading and may lead to optimistic estimates of the robustness of liveness detection in practical use cases.