Abstract
This article presents a systematic review of Multiple Instance Learning (MIL) applied to image classification, specifically highlighting its applications in medical imaging. Motivated by the need for a comprehensive and up-to-date analysis due to the scarcity of recent reviews, this study uses defined selection criteria to systematically assess the quality and synthesize data from relevant studies. Focusing on MIL, a subfield of machine learning that deals with learning from sets of instances or bags, this review is crucial for medical diagnosis, where accurate lesion detection is a challenge. The review details the methodologies, advances and practical implementations of MIL, emphasizing the attention-grabbing and transformative mechanisms that improve the analysis of medical images. Challenges such as the need for extensive annotated datasets and significant computational resources are discussed. In addition, the review covers three main topics: the characterization of MIL algorithms in various imaging domains, a detailed evaluation of performance metrics, and a critical analysis of data structures and computational resources. Despite these challenges, MIL offers a promising direction for research with significant implications for medical diagnostics, highlighting the importance of continued exploration and improvement in this area.

Abstract
Early and accurate disease diagnosis is pivotal for effective phytosanitary management strategies in agriculture. Hyperspectral sensing has emerged as a promising tool for early disease detection, yet challenges remain in effectively harnessing its potential. This study compares parametric spectral Vegetation Indices (VIs) and a nonparametric Gaussian Process Classification based on an Automated Spectral Band Analysis Tool (GPC-BAT) for diagnosing plant bacterial diseases using hyperspectral data. The study conducted experiments on tomato plants in controlled conditions and kiwi plants in field settings to assess the performance of VIs and GPC-BAT. In the tomato experiment, the modeling processes were applied to classify the spectral data measured on the healthy class of plants (sprayed with water only) and discriminate them from the data captured on plants inoculated with the two bacterial suspensions (108 CFU mL-1). In the kiwi experiment, the standard modeling results of the spectral data collected on nonsymptomatic plants were compared to the ones obtained using symptomatic plants' spectral data. VIs, known for their simplicity in extracting biophysical information, successfully distinguished healthy and diseased tissues in both plant species. The overall accuracy achieved was 63% and 71% for tomato and kiwi, respectively. Limitations were observed, particularly in differentiating specific disease infections accurately. On the other hand, GPC-BAT, after feature reduction, showcased enhanced accuracy in identifying healthy and diseased tissues. The overall accuracy ranged from 70% to 75% in the tomato and kiwi case studies. Despite its effectiveness, the model faced challenges in accurately predicting certain disease infections, especially in the early stages. Comparative analysis revealed commonalities and differences in the spectral bands identified by both approaches, with overlaps in critical regions across plant species. Notably, these spectral regions corresponded to the absorption regions of various photosynthetic pigments and structural components affected by bacterial infections in plant leaves. The study underscores the potential of hyperspectral sensing in disease diagnosis and highlights the strengths and limitations of VIs and GPC-BAT. The identified spectral features hold biological significance, suggesting correlations between bacterial infections and alterations in plant pigments and structural components. Future research avenues could focus on refining these approaches for improved accuracy in diagnosing diverse plant-pathogen interactions, thereby aiding disease diagnosis. Specifically, efforts could be directed towards adapting these methodologies for early detection, even before symptom manifestation, to better manage agricultural diseases.

Abstract
In this work, we assess the impact of self-supervised learning (SSL) approaches on the detection of gastritis atrophy (GA) and intestinal metaplasia (IM) conditions. GA and IM are precancerous gastric lesions. Detecting these lesions is crucial to intervene early and prevent their progression to cancer. A set of experiments is conducted over the Chengdu dataset, by considering different amounts of annotated data in the training phase. Our results reveal that, when all available data is used for training, SSL approaches achieve a classification accuracy on par with a supervised learning baseline, (81.52% vs 81.76%). Interestingly, we observe that in low-data regimes (here represented as retaining only 12.5% of annotated data for training), the SSL model guarantees an accuracy gain with respect to the supervised learning baseline of approximately 1.5% (73.00% vs 71.52%). This observation hints at the potential of SSL models in leveraging unlabeled data, thus showcasing more robust performance improvements and generalization. Experimental results also show that SSL performance is significantly dependent on the specific data augmentation techniques and parameters adopted for contrastive learning, thus advocating for further investigations into the definition of optimal data augmentation frameworks specifically tailored for gastric lesion detection applications.

Abstract

Abstract
This paper introduces an advanced acoustic imaging system leveraging multibeam water column data at various frequencies to detect and classify marine litter. This study encompasses (i) the acquisition of test tank data for diverse types of marine litter at multiple acoustic frequencies; (ii) the creation of a comprehensive acoustic image dataset with meticulous labelling and formatting; (iii) the implementation of sophisticated classification algorithms, namely support vector machine (SVM) and convolutional neural network (CNN), alongside cutting-edge detection algorithms based on transfer learning, including single-shot multibox detector (SSD) and You Only Look once (YOLO), specifically YOLOv8. The findings reveal discrimination between different classes of marine litter across the implemented algorithms for both detection and classification. Furthermore, cross-frequency studies were conducted to assess model generalisation, evaluating the performance of models trained on one acoustic frequency when tested with acoustic images based on different frequencies. This approach underscores the potential of multibeam data in the detection and classification of marine litter in the water column, paving the way for developing novel research methods in real-life environments.

Abstract
Agile methodologies, initially designed for the project level, face challenges when applied at enterprise levels where complex projects and diverse stakeholders are involved. To meet this challenge, several large-scale agile methodologies have been proposed. However, these approaches are not flexible enough or tailored to the needs of organizations, projects, and their teams. It is in this context that hybrid methodologies have emerged. This study aims to conduct a systematic literature review to trace the evolution of hybrid scaling of agile and characterize different approaches to implement it. This study starts by assessing 1509 studies through the use of the PRISMA 2020 framework and identifies 38 relevant studies in this field. The findings indicate that the majority of studies are from 2021 onwards and that qualitative methodologies supported by case studies predominate, making it possible to characterize tailoring processes in these organizations. Moreover, the implementation of hybrid scaling of agile is supported by the paradigm of ambidextrous strategy, a combination of agile with traditional project management methodologies, and continuous improvements. This study contributes insights into navigating the complexities of agile scaling, offering practical guidance for organizations seeking to optimize their project management practices.