Abstract
This paper presents an innovative approach to solve the product-launch planning problem in the pharmaceutical industry, with uncertainty on the product demand and on clinical trials. A mixed integer linear programming (MILP) model, incorporating Monte Carlo simulation (MCS), was developed for optimizing the process design (process-unit allocation and scale-up decisions) and for capacity planning (acquisition of new units), considering the products that still require development, and the products that are already in commercialization. MCS is performed in a two-step procedure, based on Normal and Bernoulli distributions, in order to capture the effects of demand variability and trials pass-fail uncertainty, respectively. Product-launch decisions are made taking into account the probability distributions of alternative process designs, of new capacity requirements, and of the coefficients of the objective function. The applicability of the proposed solution approach is demonstrated in an illustrative case study.

Abstract
Software engineering (SE) is an area with a wide range of concepts and knowledge. Such diversity of topics, requires the application of different teaching and learning techniques for an effective education. Serious Games is one of such techniques, yet its design tends to be complex, currently lacking a map of game design standards that comply with SE education requirements. This paper presents a process to identify the game design patterns that can be effective for teaching software engineering, specifically the software project management topic. Firstly, it begins by identifying the relationship between game design patterns and teaching and learning functions based on literature review. Secondly, it filters which of those teaching and learning functions is most relevant to software project management education, according to SE education specialists. Finally, it validates the relationship between game design patterns and software project management education through an empirical study conducted with master students. The results can be used as a basis for designing and developing serious games for teaching software project management. (C) 2016 The Authors. Published by Elsevier Ltd.

Abstract
This book gathers carefully selected works in Mathematical Economics, on myriad topics including General Equilibrium, Game Theory, Economic Growth, Welfare, Social Choice Theory, Finance. It sheds light on the ongoing discussions that have brought together leading researchers from Latin America and Southern Europe at recent conferences in venues like Porto, Portugal; Athens, Greece; and Guanajuato, Mexico. With this volume, the editors not only contribute to the advancement of research in these areas, but also inspire other scholars around the globe to collaborate and research these vibrant, emerging topics.

Abstract
We propose two methods to characterize the Non-Common Path Aberrations (NCPA) on the TMT/NFIRAOS system; these techniques are known as Phase Diversity and Focal Plane Sharpening. We demonstrate the feasibility of these techniques on an experimental bench. We also explore the operational effects of Phase Diversity and how it might be best applied to a NFIRAOS-like system. In particular we explore the technique of single image Phase Diversity along with the effects of i) estimating either Zernike modes or Disk Harmonics, ii) using multiple diverse images, and III) using diversities other than focus. These operational considerations are explored in a simulation of the NFIRAOS system and we aim to find the best estimation of the NFIRAOS NCPA in the presence of different levels of noise. We find a realistic estimation of NFIRAOS NCPA would be with multi-image Phase Diversity-with focus-diverse images sampled at asymmetric positions on either side of the focal plane (with no estimation of the object).

Abstract
Software transactional memory (STM) is a synchronisation paradigm which improves the parallelism and composability of modern applications executing on a multi-core architecture. However, to abort and retry a transaction multiple times may have a negative impact on the temporal characteristics of a real-time task set. This paper addresses this issue: It provides a framework in which an upper-bound on the worst-case response time of each task is derived, assuming that tasks are scheduled by following either the Non-Preemptive During Attempt (NPDA), Non-Preemptive Until Commit (NPUC) or Stack Resource Policy for Transactional Memory (SRPTM) policy.

Abstract
Although wind power generation has extended a maturity in technology, there are still many concerns regarding the optimal support of regulatory bodies for renewable resources. In this context, the regulatory body should form a market structure or consider market rules and regulations to not only attract investors to renewable power plants, but also provide an efficient market that reflects a safe and clear competition environment. In this paper, an agent-based game-theoretic model is developed to investigate the electricity market behavior under oligopoly circumstances. The proposed model reveals the potential of collusive and strategic behavior of market participants. By employing the proposed model, impacts of different supportive schemes on the behavior of the wind power producer and conventional thermal units are investigated. According to the results obtained, if the regulatory bodies do not consider strategic collusion of market participants, adverse consequences for wind power producers might happen in the long-term horizon.