Abstract
Secure Multiparty Computation (SMC) facilitates secure collaboration among multiple parties while safeguarding the privacy of their confidential data. This paper introduces a two-party quantum SMC protocol designed for evaluating binary Boolean functions using single qubits. Complexity analyses demonstrate a reduction of 66.7% in required quantum resources, achieved by utilizing single qubits instead of multi-particle entangled states. However, the quantum communication cost has increased by 40% due to the amplified exchange of qubits among participants. Furthermore, we bolster security by performing additional quantum operations along the y-axis of the Bloch sphere, effectively hiding the output from potential adversaries. We design the corresponding quantum circuit and implement the proposed protocol on the IBM Qiskit platform, yielding reliable outcomes.

Abstract

Abstract
Lung cancer stands as the most prevalent and deadliest type of cancer, with adenocarcinoma being the most common subtype. Computed Tomography (CT) is widely used for detecting tumours and their phenotype characteristics, for an early and accurate diagnosis that impacts patient outcomes. Machine learning algorithms have already shown the potential to recognize patterns in CT scans to classify the cancer subtype. In this work, two distinct pipelines were employed to perform binary classification between adenocarcinoma and non-adenocarcinoma. Firstly, radiomic features were classified by Random Forest and eXtreme Gradient Boosting classifiers. Next, a deep learning approach, based on a Residual Neural Network and a Transformer-based architecture, was utilised. Both 2D and 3D CT data were initially explored, with the Lung-PET-CT-Dx dataset being employed for training and the NSCLC-Radiomics and NSCLC-Radiogenomics datasets used for external evaluation. Overall, the 3D models outperformed the 2D ones, with the best result being achieved by the Hybrid Vision Transformer, with an AUC of 0.869 and a balanced accuracy of 0.816 on the internal test set. However, a lack of generalization capability was observed across all models, with the performances decreasing on the external test sets, a limitation that should be studied and addressed in future work.

Abstract

Abstract
Lung cancer is one of the leading causes of cancer-related deaths worldwide, mainly due to late diagnosis. Screening programs can benefit from Computer-Aided Diagnosis (CAD) systems that detect and classify lung nodules using Computed Tomography (CT) scans. A great proportion of the literature proposes deep learning models based on single and private datasets with no evaluation of their generalisation capability. The main goal of this work is to study and address the lack of generalisation to out-of-domain data (source domain different from the target domain). In this work, we propose using a ResNet architecture with 2.5D inputs capable of maintaining the spatial information of the nodules (3 input channels based on the anatomical planes). Secondly, we apply domain-specific data augmentation tailored for CT scans. Combined with data augmentation, using 2.5D inputs achieves the best results, both in in-domain data (LIDC-IDRI: N=1377 nodules; and LNDb: N=183 nodules) and in out-of-domain data (LUNGx: N=73 nodules). In in-domain data, an Area Under the Curve (AUC) of 0.914 was achieved in the internal test set and 0.746 in one of the external test sets. Notably, in out-of-domain data, where the ground-truth labels have been confirmed by biopsy, whereas the training data only involved radiologist annotation regarding the "likelihood of malignancy", AUC improves from 0.576 to 0.695, reaching a performance close to that of radiology experts. In the future, strategies should be applied to deal with the level of uncertainty of lung nodule annotations based solely on the observation of the CT scans.Clinical relevance- This work provides an automatic method for lung nodule malignancy classification based on CT scans, combined with generalisation methods that allow a good performance across different cohort populations and hospitals.

Abstract
The integration of solar photovoltaic (PV) systems and smart grids has enabled distributed energy trading, yet the development of regulatory frameworks for microgrid energy markets remains a challenge. Rising energy costs and greenhouse gas emissions necessitate innovative strategies to ensure affordable, sustainable, and reliable power for communities. This paper proposes a Community Energy Market (CEM) leveraging Linear Programming (LP) optimization to minimize energy costs and enhance renewable energy utilization. The results demonstrate that the CEM approach significantly increases energy self-sufficiency, reducing reliance on the grid. This method achieves Rs.38,830 cost saving. Furthermore, local energy trading within communities yields 68.75% % energy savings and reduces CO2 emissions by 88.01%. These findings highlight the effectiveness of the CEM model in fostering community collaboration, improving microgrid resilience, and promoting environmental sustainability. The proposed solution emphasizes the need for diversifying energy sources and adopting advanced energy market systems to deliver long-term, cost-effective, and eco-friendly energy solutions.