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Publications

2020

Forming intersectoral partnerships for social innovation in Portugal [O processo de formação de parcerias intersetoriais em iniciativas de inovação social em Portugal]

Authors
Borges, MA; Dandolini, GA; Soares, AL;

Publication
Analise Social

Abstract
The purpose of this article is to describe the process of forming intersectoral partnerships in social innovation initiatives in Portugal. The methodological approach used was the qualitative study of multiple cases through a triangulated analysis of the data. This resulted in a set of interrelated categories explaining the formation process of the partnerships: formation of the partners, means of identification, motivation of the partners to form the partnership, criteria for forming the partnership, determining factors, facilitators, and training process. We discuss the implications of this process and foment some strategies to support the development of intersectoral partnerships for social innovation initiatives.

2020

A gamification platform to foster energy efficiency in office buildings

Authors
Iria, J; Fonseca, N; Cassola, F; Barbosa, A; Soares, F; Coelho, A; Ozdemir, A;

Publication
ENERGY AND BUILDINGS

Abstract
Office buildings consume a significant amount of energy that can be reduced through behavioral change. Gamification offers the means to influence the energy consumption related to the activities of the office users. This paper presents a new mobile gamification platform to foster the adoption of energy efficient behaviors in office buildings. The gamification platform is a mobile application with multiple types of dashboards, such as (1) an information dashboard to increase the awareness of the users about their energy consumption and footprint, (2) a gaming dashboard to engage users in real-time energy efficiency competitions, (3) a leaderboard to promote peer competition and comparison, and (4) a message dashboard to send tailor-made messages about energy efficiency opportunities. The engagement and gamification strategies embedded in these dashboards exploit economic, environmental, and social motivations to stimulate office users to adopt energy efficient behaviors without compromising their comfort and autonomy levels. The gamification platform was demonstrated in an office building environment. The results suggest electricity savings of 20%. © 2020 Elsevier B.V.

2020

Student Research Abstract: Multimodal Deep Learning Based Approach for Cells State Classification

Authors
Silva, PR;

Publication
PROCEEDINGS OF THE 35TH ANNUAL ACM SYMPOSIUM ON APPLIED COMPUTING (SAC'20)

Abstract
With the advances of the big data era in biology, deep learning have been incorporated in analysis pipelines trying to transform biological information into valuable knowledge. Deep learning demonstrated its power in promoting bioinformatics field including sequence analysis, bio-molecular property and function prediction, automatic medical diagnosis and to analyse cell imaging data. The ambition of this work is to create an approach that can fully explore the relationships across modalities and subjects through mining and fusing features from multi-modality data for cell state classification. The system should be able to classify cell state through multimodal deep learning techniques using heterogeneous data such as biological images, genomics and clinical annotations. Our pilot study addresses the data acquisition process and the framework capable to extract biological parameters from cell images.

2020

A strategy for electricity buyers in futures markets

Authors
Monteiro, C; Ramirez Rosado, IJ; Fernandez Jimenez, LA;

Publication
E3S Web of Conferences

Abstract
This paper presents an original trading strategy for electricity buyers in futures markets. The strategy applies a medium-term electricity price forecasting model to predict the monthly average spot price which is used to evaluate the Risk Premium for a physical delivery under a monthly electricity futures contract. The proposed trading strategy aims to provide an advantage relatively to the traditional strategy of electricity buyers (used as benchmark), anticipating the good/wrong decision of buying electricity in the futures market instead in the day-ahead market. The mid-term monthly average spot price forecasting model, which supports the trading strategy, uses only information available from futures and spot markets at the decision moment. Both the new trading strategy and the monthly average spot price forecasting model, proposed in this paper, have been successfully tested with historical data of the Iberian Electricity Market (MIBEL), although they could be applied to other electricity markets. © 2020 The Authors, published by EDP Sciences.

2020

Motivating Students to Learn Computer Programming in Higher Education: The SimProgramming Approach

Authors
Nunes, RR; Cruz, G; Pedrosa, D; Maia, AM; Morgado, L; Paredes, H; Cravino, J; Martins, P;

Publication
TECH-EDU

Abstract
This paper presents an action research study aiming to motivate undergraduate students to develop their computer programming learning skills, particularly within the transition from beginner to proficient level. The SimProgramming motivational approach is presented as a didactic proposal for this context. From the results of this iterative research process, we concluded that SimProgramming is a promising tool for teaching computer programming skills in intermediate classes, with potential to be used and/or applied in other educational contexts.

2020

Combined burden and functional impact tests for cancer driver discovery using DriverPower

Authors
Shuai, S; Abascal, F; Amin, SB; Bader, GD; Bandopadhayay, P; Barenboim, J; Beroukhim, R; Bertl, J; Boroevich, KA; Brunak, S; Campbell, PJ; Carlevaro Fita, J; Chakravarty, D; Chan, CWY; Chen, K; Choi, JK; Deu Pons, J; Dhingra, P; Diamanti, K; Feuerbach, L; Fink, JL; Fonseca, NA; Frigola, J; Gambacorti Passerini, C; Garsed, DW; Gerstein, M; Getz, G; Guo, Q; Gut, IG; Haan, D; Hamilton, MP; Haradhvala, NJ; Harmanci, AO; Helmy, M; Herrmann, C; Hess, JM; Hobolth, A; Hodzic, E; Hong, C; Hornshøj, H; Isaev, K; Izarzugaza, JMG; Johnson, R; Johnson, TA; Juul, M; Juul, RI; Kahles, A; Kahraman, A; Kellis, M; Khurana, E; Kim, J; Kim, JK; Kim, Y; Komorowski, J; Korbel, JO; Kumar, S; Lanzós, A; Larsson, E; Lawrence, MS; Lee, D; Lehmann, KV; Li, S; Li, X; Lin, Z; Liu, EM; Lochovsky, L; Lou, S; Madsen, T; Marchal, K; Martincorena, I; Martinez Fundichely, A; Maruvka, YE; McGillivray, PD; Meyerson, W; Muiños, F; Mularoni, L; Nakagawa, H; Nielsen, MM; Paczkowska, M; Park, K; Park, K; Pedersen, JS; Pons, T; Pulido Tamayo, S; Raphael, BJ; Reimand, J; Reyes Salazar, I; Reyna, MA; Rheinbay, E; Rubin, MA; Rubio Perez, C; Sahinalp, SC; Saksena, G; Salichos, L; Sander, C; Schumacher, SE; Shackleton, M; Shapira, O; Shen, C; Shrestha, R; Shuai, S; Sidiropoulos, N; Sieverling, L; Sinnott Armstrong, N; Stein, LD; Stuart, JM; Tamborero, D; Tiao, G; Tsunoda, T; Umer, HM; Uusküla Reimand, L; Valencia, A; Vazquez, M; Verbeke, LPC; Wadelius, C; Wadi, L; Wang, J; Warrell, J; Waszak, SM; Weischenfeldt, J; Wheeler, DA; Wu, G; Yu, J; Zhang, J; Zhang, X; Zhang, Y; Zhao, Z; Zou, L; von Mering, C; Gallinger, S; Stein, L;

Publication
Nature Communications

Abstract
The discovery of driver mutations is one of the key motivations for cancer genome sequencing. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we describe DriverPower, a software package that uses mutational burden and functional impact evidence to identify driver mutations in coding and non-coding sites within cancer whole genomes. Using a total of 1373 genomic features derived from public sources, DriverPower’s background mutation model explains up to 93% of the regional variance in the mutation rate across multiple tumour types. By incorporating functional impact scores, we are able to further increase the accuracy of driver discovery. Testing across a collection of 2583 cancer genomes from the PCAWG project, DriverPower identifies 217 coding and 95 non-coding driver candidates. Comparing to six published methods used by the PCAWG Drivers and Functional Interpretation Working Group, DriverPower has the highest F1 score for both coding and non-coding driver discovery. This demonstrates that DriverPower is an effective framework for computational driver discovery. © 2020, The Author(s).

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