Abstract
This study presents variability assessment of real time measurements from in-vivo internal joint loads with instrumented implant during post-operative (PO) recovery process from total hip arthroplasty on daily living gait activities. A total of 112 trials walking supported by crutches in both hands, contralateral and ipsilateral sides, walking on treadmill at constant velocities, accelerating, decelerating and free walking, were assessed from 9 different patients ranging 0.3 to 76-month PO. Variability was assessed based on standard deviation of the vertical joint load normalized to each subject body weight with this metric adequacy to monitor PO recover.

Abstract
The current surge in the deployment of web applications underscores the need to consider users' individual preferences in order to enhance their experience. In response to this, an innovative approach is emerging that focuses on the detailed analysis of interaction data captured by web browsers. These data, which includes metrics such as the number of mouse clicks, keystrokes, and navigation patterns, offer insights into user behavior and preferences. By leveraging this information, developers can achieve a higher degree of personalization in web applications, particularly in the context of interactive elements such as online games. This paper presents the WebTraceSense project, which aims to pioneer this approach by developing a framework that encompasses a backend and frontend, advanced visualization modules, a DevOps cycle, and the integration of AI and statistical methods. The backend of this framework will be responsible for securely collecting, storing, and processing vast amounts of interaction data from various websites. The frontend will provide a user-friendly interface that allows developers to easily access and utilize the platform's capabilities. One of the key components of this framework is the visualization modules, which will enable developers to monitor, analyze, and interpret user interactions in real time, facilitating more informed decisions about user interface design and functionality. Furthermore, the WebTraceSense framework incorporates a DevOps cycle to ensure continuous integration and delivery, thereby promoting agile development practices and enhancing the overall efficiency of the development process. Moreover, the integration of AI methods and statistical techniques will be a cornerstone of this framework. By applying machine learning algorithms and statistical analysis, the platform will not only personalize user experiences based on historical interaction data but also infer new user behaviors and predict future preferences. In order to validate the proposed components, a case study was conducted which demonstrated the usefulness of the WebTraceSense framework in the creation of visualizations based on an existing dataset.

Abstract
The expected development and massification of Local Energy Markets (LEM), in particular the ones associated with Renewable Energy Communities, poses new challenges, and requires new operations strategies to their promoters, aggregators, and end-consumers. One of the mechanisms that can be used to speed up the spreading of this kind of market is the use of Demand Response (DR) programs since they can be designed to increase the community's savings and profits. In this framework, the end customers are induced to change their normal consumption patterns by temporarily reducing and/or shifting their electricity consumption away from periods with low local generation in response to a signal from a service provider, i.e., aggregator. To this purpose, this paper presents an Agent Based Model (ABM) using the Q-Learning mechanism to implement and to simulate a LEM and its interaction with the Wholesale Market (WSM), using also and incentive-based DR program. The overall objective of this design is to decrease average energy costs by moving the demand to periods of large availability of wind or solar resources or to store energy for future use. The developed model was tested considering real data regarding energy consumption and PV generation. The proposed paper describes and discusses the obtained market strategy and the profits that can be obtained with this approach.

Abstract
AbstractBreakthroughs in sequencing technologies led to an exponential growth of genomic data, providing unprecedented biological in-sights and new therapeutic applications. However, analyzing such large amounts of sensitive data raises key concerns regarding data privacy, specifically when the information is outsourced to third-party infrastructures for data storage and processing (e.g., cloud computing). Current solutions for data privacy protection resort to centralized designs or cryptographic primitives that impose considerable computational overheads, limiting their applicability to large-scale genomic analysis.We introduce Gyosa, a secure and privacy-preserving distributed genomic analysis solution. Unlike in previous work, Gyosafollows a distributed processing design that enables handling larger amounts of genomic data in a scalable and efficient fashion. Further, by leveraging trusted execution environments (TEEs), namely Intel SGX, Gyosaallows users to confidentially delegate their GWAS analysis to untrusted third-party infrastructures. To overcome the memory limitations of SGX, we implement a computation partitioning scheme within Gyosa. This scheme reduces the number of operations done inside the TEEs while safeguarding the users’ genomic data privacy. By integrating this security scheme inGlow, Gyosaprovides a secure and distributed environment that facilitates diverse GWAS studies. The experimental evaluation validates the applicability and scalability of Gyosa, reinforcing its ability to provide enhanced security guarantees. Further, the results show that, by distributing GWASes computations, one can achieve a practical and usable privacy-preserving solution.

Abstract
Radiography is the primary modality for diagnosing canine hip dysplasia (CHD), with visual assessment of radiographic features sometimes used for accurate diagnosis. However, these features typically constitute small regions of interest (ROI) within the overall image, yet they hold vital diagnostic information and are crucial for pathological analysis. Consequently, automated detection of ROIs becomes a critical preprocessing step in classification or segmentation systems. By correctly extracting the ROIs, the efficiency of retrieval and identification of pathological signs can be significantly improved. In this research study, we employed the most recent iteration of the YOLO (version 8) model to detect hip joints in a dataset of 133 pelvic radiographs. The best-performing model achieved a mean average precision (mAP50:95) of 0.81, indicating highly accurate detection of hip regions. Importantly, this model displayed feasibility for training on a relatively small dataset and exhibited promising potential for various medical applications.

Abstract
Diabetic foot is a serious complication that poses significant risks for diabetic patients. The resulting reduction in protective sensitivity in the plantar region requires early detection to prevent ulceration and ultimately amputation. The primary method employed for evaluating this sensitivity loss is the 10 gf Semmes-Weinstein monofilament test, commonly used as a first-line procedure. However, the lack of calibration in existing devices often introduces decision errors due to unreliable feedback. In this article, the mechanical behavior of a monofilament was analytically modeled, seeking to promote awareness of the impact of different factors on clinical decisions. Furthermore, a new device for the automation of the metrological evaluation of the monofilament is described. Specific testing methodologies, used for the proposed equipment, are also described, creating a solid base for the establishment of future calibration guidelines. The obtained results showed that the tested monofilaments had a very high error compared to the 10 gf declared by the manufacturers. To improve the precision and reliability of assessing the sensitivity loss, the frequent metrological calibration of the monofilament is crucial. The integration of automated verification, simulation capabilities, and precise measurements shows great promise for diabetic patients, reducing the likelihood of adverse outcomes.