Abstract
Determining subgraph frequencies is at the core of several graph mining methodologies such as discovering network motifs or computing graphlet degree distributions. Current state-of-the-art algorithms for this task either take advantage of common patterns emerging on the networks or target a set of specific subgraphs for which analytical calculations are feasible. Here, we propose a novel network generic framework revolving around a new data-structure, a Condensed Graph, that combines both the aforementioned approaches, but generalized to support any subgraph topology and size. Furthermore, our methodology can use as a baseline any enumeration based census algorithm, speeding up its computation. We target simple topologies that allow us to skip several redundant and heavy computational steps using combinatorics. We were are able to achieve substantial improvements, with evidence of exponential speedup for our best cases, where these patterns represent up to 97% of the network, from a broad set of real and synthetic networks.

Abstract
In this work, we propose a novel algorithm for heart sound segmentation. The proposed approach is based on the combination of two families of state-of-the-art solutions for such problem, hidden Markov models and deep neural networks, in a single training framework. The proposed approach is tested with heart sounds from the PhysioNet dataset and it is shown to achieve an average sensitivity of 93.9% and an average positive predictive value of 94.2% in detecting the boundaries of fundamental heart sounds.

Abstract
Stomach cancer is the third deadliest type of cancer in the world (0.86 million deaths in 2017). In 2035, a 20% increase will be observed both in incidence and mortality due to demographic effects if no interventions are foreseen. Upper GI endoscopy (UGIE) plays a paramount role in early diagnosis and, therefore, improved survival rates. On the other hand, human and technical factors can contribute to misdiagnosis while performing UGIE. In this scenario, artificial intelligence (AI) has recently shown its potential in compensating for the pitfalls of UGIE, by leveraging deep learning architectures able to efficiently recognize endoscopic patterns from UGIE video data. This work presents a review of the current state-of-the-art algorithms in the application of AI to gastroscopy. It focuses specifically on the threefold tasks of assuring exam completeness (i.e., detecting the presence of blind spots) and assisting in the detection and characterization of clinical findings, both gastric precancerous conditions and neoplastic lesion changes. Early and promising results have already been obtained using well-known deep learning architectures for computer vision, but many algorithmic challenges remain in achieving the vision of AI-assisted UGIE. Future challenges in the roadmap for the effective integration of AI tools within the UGIE clinical practice are discussed, namely the adoption of more robust deep learning architectures and methods able to embed domain knowledge into image/video classifiers as well as the availability of large, annotated datasets.

Abstract

Abstract
This paper is concerned with the semantic segmentation within domain-specific contexts, such as those pertaining to biology, physics, or material science. Under these circumstances, the objects of interest are often irregular and have fine structure, i.e., detail at arbitrarily small scales. Empirically, they are often understood as self-similar processes, a concept grounded in Multifractal Analysis. We find that this multifractal behaviour is carried out through a convolutional neural network (CNN), if we view its channel-wise responses as self-similar measures. A function of the local singularities of each measure we call Singularity Stregth Recalibration (SSR) is set forth to modulate the response at each layer of the CNN. SSR is a lightweight, plug-in module for CNNs. We observe that it improves a baseline U-Net in two biomedical tasks: skin lesion and colonic polyp segmentation, by an average of 1.36% and 1.12% Dice score, respectively. To the best of our knowledge, this is the first time multifractal-analysis is conducted end-to-end for semantic segmentation.

Abstract
Gastric Intestinal Metaplasia (GIM) is one of the precancerous conditions in the gastric carcinogenesis cascade and its optical diagnosis during endoscopic screening is challenging even for seasoned endoscopists. Several solutions leveraging pre-trained deep neural networks (DNNs) have been recently proposed in order to assist human diagnosis. In this paper, we present a comparative study of these architectures in a new dataset containing GIM and non-GIM Narrow-band imaging still frames. We find that the surveyed DNNs perform remarkably well on average, but still measure sizeable interfold variability during cross-validation. An additional ad-hoc analysis suggests that these baseline architectures may not perform equally well at all scales when diagnosing GIM.