Abstract
Currently, methylprednisolone sodium succinate (MPSS) is the standard treatment following acute spinal cord injury (SCI) as a consequence of the results obtained from the National Acute Spinal Cord Injury Studies. However, many have questioned the efficacy of MPSS because of its marginal effects. Additionally there has been criticism of both study design and statistical interpretation. The functional consequences of experimental SCI have been assessed in many ways. The purpose of this investigation was to determine the effects of MPSS vs. saline solution (SS) following moderate T10 contusion injury in rat. Functional recovery was evaluated using the 21-point Basso, Beattie and Bresnahan (BBB) locomotor recovery scale, the inclined plane, the beam walk, footprint analysis and the horizontal ladder. To optimize the precision and accuracy of functional results we examined the locomotion on a treadmill using three-dimensional (3D) analysis. Stereology was used to estimate the amount of damaged tissue. The results of the traditional functional methods showed that administration of the NASCIS dosage of MPSS following acute spinal cord contusion did not lead to any significant differences in the functional recovery of MPSS- vs. SS-treated animals. More importantly, the results of the 3D kinematic showed that the MPSS administration did not affect the flexion/extension of the hip, knee and ankle joints during the step cycle. Finally, stereological results revealed no statistically significant differences between the two experimental groups. Altogether, our results support data previously reported by several authors, suggesting that MPSS does not lead to improved functional outcome following experimental acute SCI.

Abstract
The spread of the Internet throughout society has sparked a revolution in the way many areas of knowledge are promoted. Geographic Information Systems (GIS) are, potentially, such an area. By distributing geospatial information and ways to manipulate it across the Web, a universal broadcast service is achieved, allowing users to access data anywhere. Geographic Information (GI) is usually the realm of specialized companies, and the client's role is often limited to consuming such information. This project aims to conceive a prototype of an architecture that allows the visualization of the Geographic Information System of University of Tras-os-Montes and Alto Douro. This prototype will also be used to feed other systems, also being developed, like navigation systems based on GPS to help people with disabilities, namely, blind users.

Abstract
A digital image correlation (DIC) algorithm for displacement measurements combining cross-correlation and a differential technique was validated through a set of experimental tests. These tests consisted of in-plane rigid-body translation and rotation tests, a tensile mechanical test, and a mode I fracture test. The fracture mechanical test, in particular, was intended to assess the accuracy of the method when dealing with discontinuous displacement fields, for which subset-based image correlation methods usually give unreliable results. The proposed algorithm was systematically compared with the Aramis (R) DIC-2D commercial code by processing the same set of images. When processing images from rigid-body and tensile tests (associated with continuous displacement fields), the two methods provided equivalent results. When processing images from the fracture mechanical test, however, the proposed method obtained a better qualitative description of the discontinuous displacements. Moreover, the proposed method gave a more reliable estimation of both crack length and crack opening displacement of the fractured specimen.(C) (C) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.OE.51.4.043602]

Abstract
Computerized analysis of rat gait is becoming an invaluable technique used by some peripheral nerve investigators for the evaluation of function. In this article we describe the use of a biomechanical model of the foot and ankle that allows a quantitative assessment and description of the ankle angle, reflecting plantarflexion and dorsiflexion during the stance phase of gait. Kinematic data of 144 trial walks from 36 normal rats were recorded with a high-speed digital image camera at 225 images per second. The ankle angular changes associated with the specific temporal events of foot placement on the ground through the stance phase were assessed. The information obtained was used to propose a new subdivision of the stance phase in the rat into three major components. This approach will provide a helpful research tool to analyze gait data that rely on the accurate determination of spatiotemporal foot events. (C) 2002 Wiley Periodicals, Inc.

Abstract
Peripheral nerve researchers frequently use the rat sciatic nerve crush model in order to test different therapeutic approaches. The purpose of this study was to determine the sequence of changes after an axonotmetic injury by means of a biomechanical model of the foot and ankle, and compare them with walking track analysis, over a fixed period of time. A kinematic analysis program was used to acquire ankle motion data for further analysis. Although repeated measures analysis of variance showed significant cumulative changes induced by the crush lesion for both ankle kinematic parameters and sciatic functional index, post-hoc multiple comparisons by the Student-Neuman-Keuls test revealed significant differences between week 0 and week 8 only for ankle kinematics. These results are of importance in showing the superiority of ankle kinematics in detecting small biomechanical deficits related to hyperexcitability of the plantarflexor muscles, in contrast with walking track analysis, which showed full motor functional recovery 8 weeks after the crush lesion.

Abstract
In experimental peripheral nerve studies, the rat sciatic nerve model is widely used to examine functional outcome following nerve injury and repair. A variety of evaluation methods exist in the literature, but an adequate selection continues to be a critical point for the researcher. Rats with sciatic nerve injury typically ambulate with an external rotation of the foot. A new functional assessment instrument, the toe out angle (TOA) is quantified using computerized gait analysis. We compared Sciatic Functional Index (SFI) with TOA parameter after peripheral nerve transection and entubulation repair. We found a good correlation between SFI and TOA measurements in terms of predicting functional recovery. Moreover, the TOA provides information on the biomechanical consequences of the external rotation of the foot in the stance phase of walking.