2026
Authors
Brito, CV; Ferreira, PG; Paulo, JT;
Publication
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS
Abstract
Breakthroughs in sequencing technologies led to an exponential growth of genomic data, providing novel biological insights and therapeutic applications. However, analyzing large amounts of sensitive data raises key data privacy concerns, specifically when the information is outsourced to untrusted third-party infrastructures for data storage and processing (e.g., cloud computing). We introduce Gyosa, a secure and privacy-preserving distributed genomic analysis solution. By leveraging trusted execution environments (TEEs), Gyosa allows users to confidentially delegate their GWAS analysis to untrusted infrastructures. Gyosa implements a computation partitioning scheme that reduces the computation done inside the TEEs while safeguarding the users' genomic data privacy. By integrating this security scheme in Glow, Gyosa provides a secure and distributed environment that facilitates diverse GWAS studies. The experimental evaluation validates the applicability and scalability of Gyosa, reinforcing its ability to provide enhanced security guarantees.
2026
Authors
Adriano C. L. Mourthé; Evelin Amorim; Carlos E. Mello; Alípio Jorge;
Publication
Communications in computer and information science
Abstract
2026
Authors
Vale, J; Silva, VF; Silva, ME; Silva, F;
Publication
CoRR
Abstract
Time series data are essential for a wide range of applications, particularly in developing robust machine learning models. However, access to high-quality datasets is often limited due to privacy concerns, acquisition costs, and labeling challenges. Synthetic time series generation has emerged as a promising solution to address these constraints. In this work, we present a framework for generating synthetic time series by leveraging complex networks mappings. Specifically, we investigate whether time series transformed into Quantile Graphs (QG) -- and then reconstructed via inverse mapping -- can produce synthetic data that preserve the statistical and structural properties of the original. We evaluate the fidelity and utility of the generated data using both simulated and real-world datasets, and compare our approach against state-of-the-art Generative Adversarial Network (GAN) methods. Results indicate that our quantile graph-based methodology offers a competitive and interpretable alternative for synthetic time series generation.
2026
Authors
Pereira, I; Silva, I; Silva, ME;
Publication
AIP Conference Proceedings
Abstract
Analyzing time series of counts often encounters the challenge of missing data, which can significantly hinder the accuracy and reliability of statistical models. This study addresses this issue by employing Poisson first-order integer-valued au-toregressive (PoINAR) models in conjunction with the Gibbs sampler with data augmentation. This method is particularly effective as it accounts for both the mechanisms behind missing data and the intrinsic serial correlation within the time series. Two distinct approaches to data augmentation are explored and compared in this work and illustrated using both simulated and real data. © 2026 Author(s).
2026
Authors
Dias, E; Antunes, C; Ilarri, M; Cunha, J; Silva, ME;
Publication
FISHES
Abstract
Atlantic salmon populations have declined in many regions and are affected by several natural and anthropogenic factors throughout their lives. We investigated the role of environmental drivers and the effect of dam construction on the trend in catches of spawning adults of a migratory population currently at risk. For this purpose, we examined the salmon catches from 1914 to 2020 in the Minho River (NW Portugal, SW Europe), located at the southern limit of this species' distribution. There was a decline in catches over time with an inverse and significant relationship between the trend in catches and lagged temperature. Delayed effects of this type may indicate temperature influences on survival during early life history stages. Similarly, the trend in catches decreased with the increasing number of dams. A forecast model built for the period before the construction of the first major dam in this river (before 1955), including lagged temperature, resulted in a decreasing trend in the number of catches. This demonstrates that catches would have declined due to temperature effects even without dam construction. This does not diminish the role of dams in the observed decline; rather, it reveals that temperature-driven declines would have occurred independently. Nonetheless, efficient management and conservation of this imperiled population require further detailed biological information on the number of returning spawning adults and salmons' survival throughout their life cycle.
2026
Authors
Duarte Nunes, G; Pinto da Silva, J; Magalhães, L; Sousa, R;
Publication
Abstract
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