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Publications

Publications by CTM

2025

Tartrazine for Optical Clearing of Tissues: Stability and Diffusion Issues

Authors
Guerra, AR; Oliveira, LR; Rodrigues, GO; Pinheiro, MR; Carvalho, MI; Tuchin, VV; Oliveira, LM;

Publication
JOURNAL OF BIOPHOTONICS

Abstract
Measuring the density of tartrazine (TZ) powder allowed to develop a protocol for fast preparation of aqueous solutions with a desired concentration. The stability time of these solutions decreases exponentially with the increase of TZ concentration: solutions with TZ concentrations below 25% remain stable for more than 24 h, while the solution with 60% TZ remains stable only for 35 min. To validate the developed protocol, muscle samples were immersed in the 40% TZ solution and, as expected, the tissue transparency increased smoothly and exponentially during the whole treatment of 30 min. The diffusion time of TZ in ex vivo skeletal muscle was quantitatively determined with high accuracy as tau TZ = 5.39 +/- 0.49 min for sample thickness of 0.5 mm. By measuring the refractive index of TZ solutions during preparation, it will be easier to prepare such solutions in a fast manner for future research on tissue optical clearing.

2025

Quartic soliton solutions of a normal-dispersion-based mode-locked laser

Authors
Facao, M; Malheiro, D; Carvalho, MI;

Publication
PHYSICAL REVIEW A

Abstract
We studied the characteristics, regions of existence, and stability of different types of solitons for a distributed model of a mode-locked laser whose dispersion is purely quartic and normal. Among the different types of solitons, we identified three main branches that are named according to their different amplitude: low, medium, and high amplitude solitons. It was found that the first solitons are always unstable while the latter two exist and are stable in relatively large regions of the parameter space. Moreover, the stability regions of medium and high amplitude solitons overlap over a certain range of parameters, manifesting effects of bistability. The energy of high amplitude solitons increases quadratically with their width, whereas the energy of medium amplitude solitons may decrease or increase with the width depending on the parameter region. Furthermore, we have investigated the long term evolution of the continuous-wave solutions under modulational instability, showing that medium amplitude solitons can arise in this scenario. Additionally, we assessed the effects of second- and third-order dispersion on medium and high amplitude solitons and found that both remain stable in the presence of these terms.

2025

Dissipative pulses stabilized by nonlinear gradient terms: A review of their dynamics and their interaction

Authors
Descalzi, O; Facao, M; Carvalho, MI; Cartes, C; Brand, HR;

Publication
PHYSICA D-NONLINEAR PHENOMENA

Abstract
We study the dynamics as well as the interaction of stable dissipative solitons (DSs) of the cubic complex Ginzburg-Landau equation which are stabilized only by nonlinear gradient (NLG) terms. First we review stationary, periodic, quasi-periodic, and chaotic solutions. Then we investigate sudden transitions to chaotic from periodic and vice versa as a function of one parameter, as well as different outcomes, for fixed parameters, when varying the initial condition. In addition, we present a quasi-analytic approach to evaluate the separation of nearby trajectories for the case of stationary DSs as well as for periodic DSs, both stabilized by nonlinear gradient terms. In a separate section collisions between different types of DSs are reviewed. First we present a concise review of collisions of DSs without NLG terms and then the results of collisions between stationary DSs stabilized by NLG terms are summarized focusing on the influence of the nonlinear gradient term associated with the Raman effect. We point out that both, meandering oscillatory bound states as well as bound states with large amplitude oscillations appear to be specific for coupled cubic complex Ginzburg-Landau equations with a stabilizing cubic nonlinear gradient term.

2025

Tutorial on the Use of the Photon Diffusion Approximation for Fast Calculation of Tissue Optical Properties

Authors
Pinheiro, MR; Carvalho, MI; Oliveira, LM;

Publication
JOURNAL OF BIOPHOTONICS

Abstract
Computer simulations, which are performed at a single wavelength at a time, have been traditionally used to estimate the optical properties of tissues. The results of these simulations need to be interpolated. For a broadband estimation of tissue optical properties, the use of computer simulations becomes time consuming and computer demanding. When spectral measurements are available for a tissue, the use of the photon diffusion approximation can be done to perform simple and direct calculations to obtain the broadband spectra of some optical properties. The additional estimation of the reduced scattering coefficient at a small number of discrete wavelengths allows to perform further calculations to obtain the spectra of other optical properties. This study used spectral measurements from the heart muscle to explain the calculation pipeline to obtain a complete set of the spectral optical properties and to show its versatility for use with other tissues for various biophotonics applications.

2025

Optimizing 5G network slicing with DRL: Balancing eMBB, URLLC, and mMTC with OMA, NOMA, and RSMA

Authors
Malta, S; Pinto, P; Fernández-Veiga, M;

Publication
JOURNAL OF NETWORK AND COMPUTER APPLICATIONS

Abstract
The advent of 5th Generation (5G) networks has introduced the strategy of network slicing as a paradigm shift, enabling the provision of services with distinct Quality of Service (QoS) requirements. The 5th Generation New Radio (5G NR) standard complies with the use cases Enhanced Mobile Broadband (eMBB), Ultra-Reliable Low Latency Communications (URLLC), and Massive Machine Type Communications (mMTC), which demand a dynamic adaptation of network slicing to meet the diverse traffic needs. This dynamic adaptation presents both a critical challenge and a significant opportunity to improve 5G network efficiency. This paper proposes a Deep Reinforcement Learning (DRL) agent that performs dynamic resource allocation in 5G wireless network slicing according to traffic requirements of the 5G use cases within two scenarios: eMBB with URLLC and eMBB with mMTC. The DRL agent evaluates the performance of different decoding schemes such as Orthogonal Multiple Access (OMA), Non-Orthogonal Multiple Access (NOMA), and Rate Splitting Multiple Access (RSMA) and applies the best decoding scheme in these scenarios under different network conditions. The DRL agent has been tested to maximize the sum rate in scenario eMBB with URLLC and to maximize the number of successfully decoded devices in scenario eMBB with mMTC, both with different combinations of number of devices, power gains and number of allocated frequencies. The results show that the DRL agent dynamically chooses the best decoding scheme and presents an efficiency in maximizing the sum rate and the decoded devices between 84% and 100% for both scenarios evaluated.

2025

A blockchain architecture with smart contracts for an additive symbiotic network - a case study

Authors
Ferreira, IA; Palazzo, G; Pinto, A; Pinto, P; Sousa, P; Godina, R; Carvalho, H;

Publication
OPERATIONS MANAGEMENT RESEARCH

Abstract
Adopting innovative technologies such as blockchain and additive manufacturing can help organisations promote the development of additive symbiotic networks, thus pursuing higher sustainable goals and implementing circular economy strategies. These symbiotic networks correspond to industrial symbiosis networks in which wastes and by-products from other industries are incorporated into additive manufacturing processes. The adoption of blockchain technology in such a context is still in a nascent stage. Using the case study method, this research demonstrates the adoption of blockchain technology in an additive symbiotic network of a real-life context. The requirements to use a blockchain network are identified, and an architecture based on smart contracts is proposed as an enabler of the additive symbiotic network under study. The proposed solution uses the Hyperledger Fabric Attribute-Based Access Control as the distributed ledger technology. Even though this solution is still in the proof-of-concept stage, the results show that adopting it would allow the elimination of intermediary entities, keep available tracking records of the resources exchanged, and improve trust among the symbiotic stakeholders (that do not have any trust or cooperation mechanisms established before the symbiotic relationship). This study highlights that the complexity associated with introducing a novel technology and the technology's immaturity compared to other data storage technologies are some of the main challenges related to using blockchain technology in additive symbiotic networks.

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