Abstract
Over the years, literature reported inumerous applications of electrochemical and surface plasmon resonance (SPR) immunoassays for biosensing but, so far, the combination of the two methods in the same sensing spot for analytical purposes is much less explored and discussed. The aim of this Review is to highlight the great potential of electrochemistry combined-SPR (eSPR) as analytical tool for screening chemically and biologically relevant (bio)molecules by combining the unique features of SPR integrated with electrochemical readout.In the first part of the Review, we describe the urgent need of innovative methods for screening clinical biological markers (General Introduction), briefly discuss general concepts of SPR and electrochemical sensing (Concepts behind eSPR biosensors) and highlight the hyphenation of two methods to developed combined biosensing systems (Set-up configuration and eSPR principles). Firstly, we briefly give an overview of the setup for implementation of eSPR technique and discuss some relevant experimental conditions to perform the combined optical and electrochemical measurements. Then, the principles and fundamentals of eSPR biosensors are presented and described. We also present representative examples of eSPR biosensors in the literature (Applications of eSPR biosensors).In the second part, we review studies on how combined electrical and plasmonic detection contributed to the biosensing field, in particular, for the successful screening of clinically relevant biomolecules, namely proteins (Detection of proteins), nucleic acids (Detection of nucleic acids), small size chemical species (Detection of small molecules) and cells (Living-cell Analysis).Finally, we discuss the current limitations of eSPR biosensors performance and suggest possible ways to overcome these limitations (Limitations and optimization) and then we explore aspects about the development of the method and its applications and discuss areas of likely future growth (Conclusions and perspectives). (c) 2022 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Abstract
A strain gauge sensor based on Fiber Bragg Grating (FBG) for diameter measurement is proposed and experimentally demonstrated. The sensor is easily fabricated inserting the FBG on the strain gauge-it was fabricated using a 3D printer-and fixing the FBG in two points of this structure. The idea is to vary the diameter of the structure. We developed two experimental setups, the first one is used to evaluate the response of the FBG to strain and the second one to assess the possibility of using the structure developed to monitor the desired parameter. The results demonstrated that the structure can be used as a way to monitor the diameter variation in some applications. The sensor presented a sensitivity of 0.5361 nm/mm and a good linear response of 0.9976 using the Strain Gauge with FBG and fused taper.

Abstract
This work addresses the role of optical sensing within the new emerging paradigm Industry 4.0. It starts with some thoughts about complex systems and their inherent need of enlarged sensorial tools. Then, the principles of optical sensing are presented with identification of the two principal types. After summarizing what is meant by Industry 4.0, it is detailed how optical sensing can contribute to the raise up of this new industrial concept, focusing on vision, physical sensing, chemical sensing, and sensor multiplexing. Emphasis is given in fiber optic sensing and, when feasible, in fiber Bragg grating sensing technology. Finally, some final remarks are delivered.

Abstract
This paper proposes a scheme to determine the optical dispersion properties of a medium using multiple localized surface plasmon resonances (SPR) in a D-shaped photonic crystal fiber (PCF) whose flat surface is covered by three adjacent gold layers of different thicknesses. Using computational simulations, we show how to customize plasmon resonances at different wavelengths, thus allowing for obtaining the second-order dispersion. The central aspect of this sensing configuration is to balance miniaturization with low coupling between the different localized plasmon modes in adjacent metallic nanostructures. The determination of the optical dispersion over a large spectral range provides information on the concentration of different constituents of a medium, which is of paramount importance when monitoring media with time-varying concentrations, such as fluidic media.

Abstract
Surface plasmon-polaritons are electromagnetic modes that can be excited at a conducting-dielec-tric interface [1]. The engineering of surface plasmon resonance (SPR) based devices is a milestone in the development of optical sensors. The ability to construct an all-optical system to confine lightwave power at subwavelength dimensions with higher levels of sensitivity and resolution in a broad spectral range are the central features that have attracted a rapid-growing interest in SPR sensors [2]. Particularly, minute variations in the refractive index of the surrounding medium (also known as analyte) change significantly the characteristics of the electromagnetic fields of a surface plasmon mode. As a consequence, the spectral shifts in the mode phase and also losses variations in the associated confined power can be used to detect analyte properties that are described in terms of the refractive index [3].

Abstract
Cylindrical structure analysis is important in several areas and can be performed through the evaluation of the diameter changes of these structures. Two important areas can be mentioned: pipelines for oil or gas distribution and the condition and growth of trees. In the tree diameter changes, monitoring is directly related to irrigation, since it depends on the water soil deficit and trees are important in the global circulation of heat and water. This diameter can change in the order of 5 mm for some species. In this paper, a strain gauge sensor based on a core diameter mismatch technique for diameter measurement is proposed and investigated. The sensor structure is formed by splicing an uncoated short section of MMF (Multimode Fiber) between two standard SMFs (Singlemode Fiber) called SMF–MMF–SMF (SMS); the MMF length is 15 mm. Two cylindrical structures were placed on a 3D printer, with different diameter sizes ((Formula presented.) : 80 mm and 110 mm), to assist in monitoring the diameter changes. The SMS sensor was placed on the printed structure and fixed at two points, such that, by reducing the diameter of the structure, the sensor presents dips or peaks shift of the transmittance spectrum due to the induced curvature and strain. Three values were used for the spacing between the fixation points ((Formula presented.)): (a) 5 mm, (b) 10 mm, and (c) 15 mm. For each choice of fixation points, (Formula presented.) = 80 mm: (a) a sensitivity of -0.876 nm/mm, (Formula presented.) of 0.9909 and a dynamic range of 5 mm; (b) a sensitivity of -0.3892 nm/mm, (Formula presented.) of 0.9954 and a dynamic range of 4 mm; and (c) a sensitivity of -0.768 nm/mm, (Formula presented.) of 0.9811 and a dynamic range of 2 mm. For (Formula presented.) = 110 mm, the sensor presents for each choice of fixation points: (a) a sensitivity of -0.22 nm/mm, (Formula presented.) of 0.9979 and a dynamic range of 8 mm; (b) a sensitivity of -0.2284 nm/mm, (Formula presented.) of 0.9888 and a dynamic range of 6 mm; and (c) a sensitivity of -0.691 nm/mm, (Formula presented.) of 0.9892 and a dynamic range of 3.5 mm. © 2021 by the authors.