Abstract
This study considers a production lot sizing and scheduling problem in the brewery industry. The underlying manufacturing process can be basically divided into two main production stages: preparing the liquids including fermentation and maturation inside the fermentation tanks; and bottling the liquids on the filling lines, making products of different liquids and sizes. This problem differs from other problems in beverage industries due to the relatively long lead times required for the fermentation and maturation processes and because the "ready" liquid can remain in the tanks for some time before being bottled. The main planning challenge is to synchronize the two stages (considering the possibility of a "ready" liquid staying in the tank until bottling), as the production bottlenecks may alternate between these stages during the planning horizon. This study presents a novel mixed integer programming model that represents the problem appropriately and integrates both stages. In order to solve real-world problem instances, MIP-based heuristics are developed, which explore the model structure. The results show that the model is able to comprise the problem requirements and the heuristics produce relatively good-quality solutions.

Abstract
The operating theater is the biggest hospital budget expenditure. The usage of surgery related resources and its intrinsic planning must be carefully devised in order to achieve better operational performance. However, from long to short term planning, the decision processes inherent to the operating theater are often the subject of empiricism. Moreover, the current hospital information systems available in Portuguese public hospitals lack a decision support system component, which could assist in achieving better planning solutions. This work reports the development of a centralized system for the operating theater planning to support decision-making tasks of surgeons, chief specialty managers, and hospital administration. Its main components concern surgery scheduling, operating theater's resource allocation and performance measurement. The enhancement of the planning processes, the increase of policy compliance, and the overall performance of the operating theater compared to the former methodologies are also discussed.

Abstract

Abstract
In this paper, we investigate a two-stage lot-sizing and scheduling problem in a spinning industry. A new hybrid method called HOPS (Hamming-Oriented Partition Search), which is a branch-and-bound based procedure that incorporates a fix-and-optimize improvement method is proposed to solve the problem. An innovative partition choice for the fix-and-optimize is developed. The computational tests with generated instances based on real data show that HOPS is a good alternative for solving mixed integer problems with recognized partitions such as the lot-sizing and scheduling problem.

Abstract
Setup operations are significant in some production environments. It is mandatory that their production plans consider some features, as setup state conservation across periods through setup carryover and crossover. The modelling of setup crossover allows more flexible decisions and is essential for problems with long setup times. This paper proposes two models for the capacitated lot-sizing problem with backlogging and setup carryover and crossover. The first is in line with other models from the literature, whereas the second considers a disaggregated setup variable, which tracks the starting and completion times of the setup operation. This innovative approach permits a more compact formulation. Computational results show that the proposed models have outperformed other state-of-the-art formulation.

Abstract