Abstract
Deep Learning has reached human-level performance in several medical tasks including clas-sification of histopathological images. Continuous effort has been made at finding effective strategies to interpret these types of models, among them saliency maps, which depict the weights of the pixels on the classification as an heatmap of intensity values, have been by far the most used for image classification. However, there is a lack of tools for the systematic evaluation of saliency maps, and existing works introduce non-natural noise such as random or uniform values. To address this issue, we propose an approach to evaluate the faithfulness of the saliency maps by introducing natural perturbations in the image, based on oppose-class substitution, and studying their impact on evaluation metrics adapted from saliency models. We validate the proposed approach on a breast cancer metastases detection dataset PatchCamelyon with 327,680 patches of histopathological images of sentinel lymph node sections. Results show that GradCAM, Guided-GradCAM and gradient-based saliency map methods are sensitive to natural perturbations and correlate to the presence of tumor evidence in the image. Overall, this approach proves to be a solution for the validation of saliency map methods without introducing confounding variables and shows potential for application on other medical imaging tasks.

Abstract
Healthcare agents, in particular in the oncology field, are currently collecting vast amounts of diverse patient data. In this context, some decision-support systems, mostly based on deep learning techniques, have already been approved for clinical purposes. Despite all the efforts in introducing artificial intelligence methods in the workflow of clinicians, its lack of interpretability - understand how the methods make decisions - still inhibits their dissemination in clinical practice. The aim of this article is to present an easy guide for oncologists explaining how these methods make decisions and illustrating the strategies to explain them. Theoretical concepts were illustrated based on oncological examples and a literature review of research works was performed from PubMed between January 2014 to September 2020, using deep learning techniques, interpretability and oncology as keywords. Overall, more than 60% are related to breast, skin or brain cancers and the majority focused on explaining the importance of tumor characteristics (e.g. dimension, shape) in the predictions. The most used computational methods are multilayer perceptrons and convolutional neural networks. Nevertheless, despite being successfully applied in different cancers scenarios, endowing deep learning techniques with interpretability, while maintaining their performance, continues to be one of the greatest challenges of artificial intelligence.

Abstract

Abstract
ydata-profiling is an open-source Python package for advanced exploratory data analysis that enables users to generate data profiling reports in a simple, fast, and efficient manner, fostering a standardized and visual understanding of the data. Beyond traditional descriptive properties and statistics, ydata-profiling follows a Data-Centric AI approach to exploratory analysis, as it focuses on the automatic detection and highlighting of complex data characteristics often associated with potential data quality issues, such as high ratios of missing or imbalanced data, infinite, unique, or constant values, skewness, high correlation, high cardinality, non-stationarity, seasonality, duplicate records, and other inconsistencies. The source code, documentation, and examples are available in the GitHub repository: https://github.com/ydataai/ydata-profiling.

Abstract
PurposeThis study analyzes the impact of packaging-free practices in food retail stores, particularly supermarkets, on customer loyalty.Design/methodology/approachBased on the literature on the impacts of sustainable practices and corporate social responsibility (CSR) policies on consumer behavior, this study defined a set of seven hypotheses that were tested using data collected from 447 consumers that regularly buy food products at supermarkets. The data were subjected to structural equation modeling using SmartPLS.FindingsThis study confirmed that packaging-free practices positively influence brand image, brand trust, satisfaction and customer loyalty. The expected positive impacts of brand image and satisfaction on customer loyalty were also confirmed. However, the expected impact of brand trust on customer loyalty was not confirmed.Practical implicationsThis article demonstrates how a competitive sector can reap benefits from implementing sustainable practices in the operational domain, particularly by offering packaging-free products at the point of purchase. Thus, as recommended, general retail stores (e.g. supermarkets) gradually increase the stores' offering of packaging-free food products, as this practice has been shown to have positive impacts not only on brand image, but also on customer satisfaction and loyalty.Originality/valueThis study extends the literature on the effects of sustainable practices on customer loyalty, by focusing on a specific practice. Furthermore, this study contributes to the advancement of research on packaging-free practices in retail by developing a research framework and providing evidence on the direct and indirect effects of this specific practice on customer loyalty.

Abstract
Being a part of society, employees' behavior can't be ignored, and it must be encouraged to sustain nature for the upcoming generation. Following the resource-based view theory, this study aims to identify the factors influencing employees toward sustainable behavior. To meet the objectives, cross-sectional data were collected from employees of manufacturing companies, and structural equation modeling was used for the analysis. The study results show a positive effect of participative decision-making and employee motivation on employees' eco-friendly innovation capabilities and behavior. Additionally, this research reveals that employee motivation partially mediates the link between participative decision-making, eco-friendly innovation capabilities, and behavior. Furthermore, this research evidenced a positive moderation of green culture on the relationship between participative decision-making and eco-friendly innovation capabilities, evidencing that the relationship is stronger when the culture is high. This research contributes to the existing literature by providing a deeper understanding of the factors influencing employees' eco-friendly innovation capabilities and behavior. It highlights the significant roles of green culture as a moderator and employee motivation as a mediator, offering novel perspectives to both theory and practice.