Abstract
This paper proposes a centralized energy management system for low voltage (LV) distribution networks. The main contribution of this model is to manage the energy serving at the local energy communities in the presence of electric vehicle supply equipment (EVSE). Unlocking the demand response potential by the EVSE at the distribution network with the contribution of the active residential prosumers has been investigated in this study under different operational planning scenarios. The developed model is based on the multi-temporal optimal power flow (MTOPF) concept while the unbalanced nature of LV networks has been addressed using unbalanced power flow equations. The aggregator can effectively manage the optimal charging of electric vehicles (EVs) by home and public chargers available at the distribution network. Simulation results on a modified unbalanced LV network illustrate that the optimal operation of EVSE minimizes the electricity costs of end-users. The simulation results show that the operating costs and systems losses reduce by 9.22% and 43.45%, respectively. These results have been obtained considering the switching actions and 100% PV power generation index using the presented MV-LV coordinated operational model. Besides, the energy storage systems improve the peak-to-average (PAR) ratio by 9.87%.

Abstract

Abstract
Background: Cardiac resynchronization therapy (CRT) is an established therapeutic option for heart failure, but despite careful selection around 30% of the patients still do not respond to this therapy. The standard electrocardiogram (ECG) is a practical and inexpensive tool to assess potential responders to CRT but with conflicting evidence regarding the value of different ECG parameters. As such, we conducted a systematic review of real-world studies to assess the value of pre-implantation standard ECG parameters in predicting response to CRT. Methods: We searched on PubMed, Scopus, and Web of Knowledge online databases to identify analytic studies and synthesized results through evidence tables. Results: Sixty-two eligible articles were included in this review. Traditional predictors of response were QRS duration =150 ms and the presence of left bundle branch block morphology. Contemporary ECG parameters, such as the presence of QRS notching or fragmentation, the S wave assessment, the time to intrinsicoid deflection (ID) in lateral leads, and a lead one ratio =12 also showed great potential in assessing response to CRT. Conclusions: This review highlights the promising capability of the standard ECG in predicting response to CRT, particularly when using more contemporary predictors, while emphasizing the necessity for further research to validate the prognostic value of these predictors. © 2025 Elsevier B.V., All rights reserved.

Abstract
This study explores the context of blood donation in Portugal, specifically aiming to understand how communication strategies can effectively recruit young blood donors aged 18 to 24. The research addresses the following question: What is the impact of communication efforts on the recruitment of young blood donors in Portugal? To answer this question, four specific objectives were set: (1) To evaluate the level of awareness among young individuals in this age group regarding blood donation; (2) to analyze and assess the communication strategies employed by the Portuguese Institute of Blood and Transplantation (IPST) to promote blood donation; (3) to investigate the motivations and barriers related to blood donation; and (4) to identify effective communication strategies for encouraging blood donation. To achieve the first objective, which is the primary focus of this article, a content analysis of 14 blood donation campaigns was conducted. For the second objective, an exploratory interview was held with a specialist from the IPST. The third objective is being addressed through a survey involving 390 young individuals, which has already been administered and revealed that over half of the respondents are not blood donors. The findings suggest that future campaigns should adopt more targeted segmentation strategies based on behavioral criteria and make greater use of integrated marketing communication to enhance effectiveness.

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Abstract
The rapid evolution of the automotive industry has driven the emergence of Connected and Autonomous Vehicles, raising significant concerns about the cybersecurity vulnerabilities inherent in their complex networks. This systematic review investigates cybersecurity in Connected and Autonomous Vehicles, focusing on internal and external networks and addressing four key research questions: (RQ1) What security controls exist in CAV networks? (RQ2) What methodologies are employed in cybersecurity studies? (RQ3) How effective are these methods, and what limitations do they present? (RQ4) What are the key themes, common approaches, and future research directions? Peer-reviewed studies published between 2019 and 2024 were included, using IEEE Xplore, Elsevier, MDPI, ACM Digital Library, and Springer as data sources. Following PRISMA 2020 guidelines, 111 relevant articles were analysed and grouped into seven themes: Authentication, Blockchain, Intrusion Detection Systems, Vehicle-to-Everything communication, Network Operation Centers, Security Operations Centers, and Systematic Reviews. The thematic synthesis highlighted study objectives, methodologies, and implemented security controls. This review identifies significant gaps in the literature, particularly in integrating Security Information and Event Management systems and the real-world validation of proposed security measures. It underscores the need for adaptive cybersecurity frameworks to address evolving threats and highlights the importance of collaboration between academia and industry. Furthermore, future research should prioritize the development of advanced security protocols, address scalability challenges, and explore the impact of emerging technologies such as Artificial Intelligence and 5G. Providing awareness and training is also essential to mitigate human error. These findings are a foundation for designing more resilient and secure Connected and Autonomous Vehicles systems.