Abstract
Gramene (http://www.gramene.org) is a knowledgebase for comparative functional analysis in major crops and model plant species. The current release, #54, includes over 1.7 million genes from 44 reference genomes, most of which were organized into 62,367 gene families through orthologous and paralogous gene classification, whole-genome alignments, and synteny. Additional gene annotations include ontology-based protein structure and function; genetic, epigenetic, and phenotypic diversity; and pathway associations. Gramene's Plant Reactome provides a knowledgebase of cellular-level plant pathway networks. Specifically, it uses curated rice reference pathways to derive pathway projections for an additional 66 species based on gene orthology, and facilitates display of gene expression, gene-gene interactions, and user-defined omics data in the context of these pathways. As a community portal, Gramene integrates best-of-class software and infrastructure components including the Ensembl genome browser, Reactome pathway browser, and Expression Atlas widgets, and undergoes periodic data and software upgrades. Via powerful, intuitive search interfaces, users can easily query across various portals and interactively analyze search results by clicking on diverse features such as genomic context, highly augmented gene trees, gene expression anatomograms, associated pathways, and external informatics resources. All data in Gramene are accessible through both visual and programmatic interfaces.

Abstract
A new approach for robust edge detection on B-mode ultrasound images of the carotid artery is proposed in this paper. The proposed method uses anisotropic Gaussian derivative filters along with non-maximum suppression over the overall artery wall orientation in local regionS. The anisotropic filters allow using a wider integration scale along the edges while preserving the edge location precision. They also perform edge continuation, resulting in the connection of isolated edge points along linear segments, which is a valuable feature for the segmentation of the artery wall layerS. However, this usually results in false edges being detected near convex contours and isolated pointS. The use of non-maximum suppression over pooled local orientations is proposed to solve this issue. Experimental results are provided to demonstrate that the proposed edge detector outperforms other common methods in the detection of the lumen-intima and media-adventia layer interfaces of the carotid vessel wallS. Additionally, the resulting edges are more continuous and precisely located.

Abstract
Evaluating scientists based on their scientific production is often a controversial topic. Nevertheless, bibliometrics and algorithmic approaches can assist traditional peer review in numerous tasks, such as attributing research grants, deciding scientific committees, or choosing faculty promotions. Traditional bibliometrics focus on individual measures, disregarding the whole data (i.e., the whole network). Here we put forward OTARIOS, a graph-ranking method which combines multiple publication/citation criteria to rank authors. OTARIOS divides the original network in two subnetworks, insiders and outsiders, which is an adequate representation of citation networks with missing information. We evaluate OTARIOS on a set of five real networks, each with publications in distinct areas of Computer Science. When matching a metric’s produced ranking with best papers awards received, we observe that OTARIOS is >20 more accurate than traditional bibliometrics. We obtain the best results when OTARIOS considers (i) the author’s publication volume and publication recency, (ii) how recently his work is being cited by outsiders, and (iii) how recently his work is being cited by insiders and how individual he his.

Abstract
Health facilities produce an increasing and vast amount of data that must be efficiently analyzed. New approaches for healthcare monitoring are being developed every day and the Internet of Things (IoT) came to fill the still existing void on real-time monitoring. A new generation of mechanisms and techniques are being used to facilitate the practice of medicine, promoting faster diagnosis and prevention of diseases. We proposed a system that relies on IoT for storing and monitoring medical sensors data with analytic capabilities. To this end, we chose two approaches for storing this data which were thoroughly evaluated. Apache HBase presents a higher rate of data ingestion, when collaborating with the Kaa IoT platform, than Apache Cassandra, exhibiting good performance storing unstructured data, as presented in a healthcare environment. The outcome of this system has shown the possibility of a large number of medical sensors being simultaneously connected to the same platform (6000 records sent by the second or 48 ECG sensors with a frequency of 125Hz). The results presented in this paper are promising and should be further investigated as a comprehensive system would benefit the patient's diagnosis but also the physicians. © 2018 IEEE.

Abstract
Clustering naturally addresses many of the challenges of data streams and many data stream clustering algorithms (DSCAs) have been proposed. The literature does not, however, provide quantitative descriptions of how these algorithms behave in different circumstances. In this paper we study how the clusterings produced by different DSCAs change, relative to the ground truth, as quantitatively different types of concept drift are encountered. This paper makes two contributions to the literature. First, we propose a method for generating real-valued data streams with precise quantitative concept drift. Second, we conduct an experimental study to provide quantitative analyses of DSCA performance with synthetic real-valued data streams and show how to apply this knowledge to real world data streams. We find that large magnitude and short duration concept drifts are most challenging and that DSCAs with partitioning-based offline clustering methods are generally more robust than those with density-based offline clustering methods. Our results further indicate that increasing the number of classes present in a stream is a more challenging environment than decreasing the number of classes. Code related to this paper is available at: https://doi.org/10.5281/zenodo.1168699, https://doi.org/10.5281/zenodo.1216189, https://doi.org/10.5281/zenodo.1213802, https://doi.org/10.5281/zenodo.1304380.

Abstract