Abstract

Abstract
The lack of physical activity and poor nutrition triggers various diseases, among them is diabetes. In this context, several researches seek ways that can mitigate these diseases to provide a better quality of life for people. Therefore, the present work aims to analyze the possible inhibitors of the enzyme Dipeptidil Peptidase 4 that hypotheses will be stipulated for the creation of new drugs through molecular docking techniques, that is, a computational simulation of combinations of drugs of the family of gliptins with other antidiabetics (metformin, glyburide and cucurbitacin). Among the results, it was observed that the antidiabetic cucurbitacin combined with the gliptines obtained greater energy during the process.

Abstract
This study presents innovative analysis at the time, frequency and phase domain for lower limb joint angular coordination assessment at sagittal plane on human vertical countermovement (CM), comparing long CM on countermovement jump (CMJ) and short CM on drop jump (DJ) from 40 cm step with squat jump (SJ) in the absence of CM. Lower limb CM and muscle stretch-shortening cycle has been pointed as playing a key role on human gait efficiency as well as on run and jump performance with an open issue on objective and quantitative measures for lower limb joint angle coordination assessment at different CM in comparison with no CM condition. Case study is considered from subject specific with 20 years old, 84 kg of body mass and 1.84 m height, selected according to best performance criteria of maximum vertical jump height during CMJ, DJ and SJ from a small sample of n = 6 sports and physical education degree students with (21.5 ± 1.4) years old, (76.7 ± 9.3) kg mass and (1.79 ± 0.06) m height, with no previous injuries, specific sport abilities or training. Calibrated image system with two digital video cameras JVC GR-VL9800 operating at 100 Hz and direct linear transformation (DLT-11) was used along with Simi Motion System and Dempster adapted model with 14 segments to track 3D coordinates of joint marks and obtain joint angles, angular velocities and accelerations at sagittal plane by inverse kinematics. Entire signal analysis was implemented on complementary time, frequency and phase domains for lower limb joint angle coordination assessment at sagittal plane on human vertical jump for comparison of long, short and without CM condition. Comprehensive signal analysis allowed detection of distinct coordination at CMJ from DJ and SJ as well from untrained tested subjects to those reported on trained subjects namely with lower coordination at untrained subjects associated to inaptitude to potentiate short CM and thus presenting lower DJ performance than trained subjects. © Springer Nature Switzerland AG 2019.

Abstract
The prevalence and availability of cloud infrastructures has made them the de facto solution for storing and archiving data, both for organizations and individual users. Nonetheless, the cloud's wide spread adoption is still hindered by dependability and security concerns, particularly in applications with large data collections where efficient search and retrieval services are also major requirements. This leads to an increased tension between security, efficiency, and search expressiveness, which current state of the art solutions try to balance through complex cryptographic protocols that tradeoff efficiency and expressiveness for near optimal security. In this paper we tackle this tension by proposing BISEN, a new provably-secure boolean searchable symmetric encryption scheme that improves these three complementary dimensions by exploring the design space of isolation guarantees offered by novel commodity hardware such as Intel SGX, abstracted as Isolated Execution Environments (IEEs). BISEN is the first scheme to enable highly expressive and arbitrarily complex boolean queries, with minimal information leakage regarding performed queries and accessed data, and verifiability regarding fully malicious adversaries. Furthermore, by exploiting trusted hardware and the IEE abstraction, BISEN reduces communication costs between the client and the cloud, boosting query execution performance. Experimental validation and comparison with the state of art shows that BISEN provides better performance with enriched search semantics and security properties.

Abstract

Abstract
The challenges of financial systems have immediate or medium-term social effects. The financial industry is constantly searching for measures to reduce these challenges, especially for those with little or no access to financial services. While current communication technologies make services more accessible through digital mobile platforms, there are still difficulties in establishing viable customer arrangements. In addition to the increased investment in financial technologies, nonbanking financial institutions have now expanded to offer more flexible services tailored to individual circumstances, especially those in isolated rural areas. This research outlines the network model of nonbanking financial institutions in Romania, as well as a microfinance model, based on the financial analysis of four national indicators of nonbanking financial institutions. Data used are presented in absolute values, from the annual numerical series for the reference period 2007-2017. The new initiatives and features incorporated in this Romanian model should be applicable elsewhere and will actively contribute to the expansion and sustainability of financial services, with a positive inclusive impact on society.