Abstract
The unprecedented pervasiveness of IoT systems is pushing this technology into increasingly stringent domains. Such application scenarios become even more challenging due to the demand for encompassing the interplay between safety and security. The IEEE 802.15.4 DSME MAC behavior aims at addressing such systems by providing additional deterministic, synchronous multi-channel access support. However, despite the several improvements over the previous versions of the protocol, the standard lacks a complete solution to secure communications. In this front, we propose the integration of TAKS, an hybrid cryptography scheme, over a standard DSME network. In this paper, we describe the system architecture for integrating TAKS into DSME with minimum impact to the standard, and we venture into analysing the overhead of having such security solution over application delay and throughput. After a performance analysis, we learn that it is possible to achieve a minor impact of 1% to 14% on top of the expected network delay, depending on the platform used, while still guaranteeing strong security support over the DSME network.

Abstract
Extremely Large Telescopes are considered worldwide as one of the highest priorities in ground-based astronomy, for they have the potential to vastly advance astrophysical knowledge with detailed studies of subjects including the first objects in the Universe, exoplanets, super-massive black holes, and the nature and distribution of the dark matter and dark energy which dominate the Universe. ESO is building its own Extremely Large optical/infrared Telescope, the ELT. This new telescope will have a 39 m main mirror and will be the largest optical/NIR telescope in the world, able to work at the diffraction limit. METIS, one of the first light instruments of the ELT, has powerful imaging and spectrographic capabilities on the thermal wavelengths. It will allow the investigation of key properties of a wide range of objects, from exoplanets to star forming regions, and it is highly complementary to other facilities such as the JWST. METIS is an extremely complex instrument, weighing almost 11 ton, and requiring high positioning and steering precisions. Here we present the ELT's METIS' Warm Support Structure. It consists on a 7 leg elevation platform, a passive hexapod capable of providing METIS with sub-millimetre and arcsecond positioning and steering resolutions, and an access platform where personnel can perform in-situ maintenance activities. The support structure weighs less than 5 ton and is capable of surviving earthquake conditions with accelerations up to 5g. The current design is supported by FEM simulations in ANSYS®, and was approved for Phase C. © 2020 SPIE

Abstract
A key issue in the performance of modern containerized distributed systems, such as big data storage and processing stacks or micro service based applications, is the placement of each container, or container pod, in virtual and physical servers. Although it has been shown that inter-application traffic is an important factor in placement decisions, as it directly indicates how components interact, it has not been possible to accurately monitor it in an application independent way, thus putting it out of reach of cloud platforms. In this paper we present an efficient black-box monitoring approach for detecting and building a weighted communication graph of collaborating processes in a distributed system that can be queried for various purposes, including adaptive placement. The key to achieving high detail and low overhead without custom application instrumentation is to use a kernel-aided event driven strategy. We evaluate a prototype implementation with micro-benchmarks and demonstrate its usefulness for container placement in a distributed data storage and processing stack (i.e., Cassandra and Spark).

Abstract
Wireless Sensor Networks (WSN) can be used to acquire environmental variables useful for decision-making, such as agriculture and forestry. Installing a WSN on the forest will allow the acquisition of ecological variables of high importance on risk analysis and fire detection. The presented paper addresses two types of WSN developed modules that can be used on the forest to detect fire ignitions using LoRaWAN to establish the communication between the nodes and a central system. The collaboration between these modules generate a heterogeneous WSN; for this reason, both are designed to complement each other. The first module, the HTW, has sensors that acquire data on a wide scale in the target region, such as air temperature and humidity, solar radiation, barometric pressure, among others (can be expanded). The second, the 5FTH, has a set of sensors with point data acquisition, such as flame ignition, humidity, and temperature. To test HTW and 5FTH, a LoRaWAN communication based on the Lorix One gateway is used, demonstrating the acquisition and transmission of forest data (simulation and real cases). Even in internal or external environments, these results allow validating the developed modules. Therefore, they can assist authorities in fighting wildfire and forest surveillance systems in decision-making.

Abstract
Fibrinogen (Fg) is a pro-inflammatory protein with pro-healing properties. Previous work showed that fibrinogen 3D scaffolds (Fg-3D) promote bone regeneration, but the cellular players were not identified. Osteoclasts are bone resorbing cells that promote bone remodeling in close crosstalk with osteoblasts. Herein, the capacity of osteoclasts differentiated on Fg-3D to degrade the scaffolds and promote osteoblast differentiation was evaluated in vitro. Fg-3D scaffolds were prepared by freeze-drying and osteoclasts were differentiated from primary human peripheral blood monocytes. Results obtained showed osteoclasts expressing the enzymes cathepsin K and tartrate resistant acid phosphatase colonizing Fg-3D scaffolds. Osteoclasts were able to significantly degrade Fg-3D, reducing the scaffold's area, and increasing D-dimer concentration, a Fg degradation product, in their culture media. Osteoclast conditioned media from the first week of differentiation promoted significantly stronger human primary mesenchymal stem/stromal cell (MSC) osteogenic differentiation, evaluated by alkaline phosphatase activity. Moreover, week 1 osteoclast conditioned media promoted earlier MSC osteogenic differentiation, than chemical osteogenesis inductors. TGF-beta 1 was found increased in osteoclast conditioned media from week 1, when compared to week 3 of differentiation. Taken together, our results suggest that osteoclasts are able to differentiate and degrade Fg-3D, producing factors like TGF-beta 1 that promote MSC osteogenic differentiation.

Abstract
Emergency department crowding has been steadily increasing, with a significant part due to non-emergent pathologies. We developed a self-service kiosk to be used by patients while waiting from triage to treatment room allocation, which collects clinical history, usual medication, main complaint and, also collects vital signs. This information is processed and presented in a comprehensive way to the medical staff in order to accelerate diagnostics and treatment selection. This work describes and analyzes the results of the usability evaluation of this kiosk, taking into account the average time per screen, the average time of a complete kiosk session, the application design and the user interaction with devices and the system. The kiosk was tested in several environments with different types of users, allowing the identification of causes of problems and difficulties experienced, as well as solutions to improve the solution. © 2020 IEEE.