Abstract
This article performs an exploratory study of the potential of flow theory and FLIGBY game to contribute to develop entrepreneurship competencies among higher education students. For this purpose, this study considers the use of a focus group consisting of eight students enrolled in the entrepreneurship course in a higher educational institution in Portugal, in which students for two months explored FLIGBY. The results obtained allowed us to conclude that FLIGBY was also suitable to be explored in the context of entrepreneurship classes. Students emphasized the potential of the game to be applied for training of management skills, the recognition of their leadership skills, and the exploration of new approaches to the management challenges. Finally, it should be noted that the benefits offered by FLIGBY were experienced differently by students with professional experience in IT and management fields. Those students emphasized the application of the game to the real world and the potential offered for FLIGBY for allowing students to explore new skills and actions. © 2021, IGI Global.

Abstract
Quality management practices are widely implemented by companies, as they constitute a competitive advantage. Nowadays it is almost mandatory to follow quality standards, in order to make a product available on the market. However, facing new production paradigms, such as Industry 4.0, questions arise about how quality management processes could benefit and adapt in the era of digital technologies. Following a literature review approach, this paper lead to the development of a table that links the relationship between quality management practices and Industry 4.0 technologies that improve quality, as it aimed. © 2021 The Authors. Published by Elsevier B.V.

Abstract
Daily activities have been increasingly supported by intelligent devices and applications. Smart devices are constantly communicating through the Internet of Things (IoT) networks, either by sending collected data and notifying the actions taken or by receiving instructions for actions to be taken. Most of this communication requires the confidentiality of data through the usage of encryption algorithms, being the Advanced Encryption Standard (AES) algorithm one of the most used. However, how do the operation modes of AES algorithm perform in a resource-constraint device? This paper aims to evaluate the impact on the time to encrypt and decrypt different sized messages in IoT devices when using each one of the five AES modes of operation and the three key sizes defined. The test scenario was implemented using two programming languages, running on a Raspberry Pi device. The results achieved infers that Python was quicker and had a more homogeneous result set than JavaScript implementation in most AES operation modes. These results help to understand the trade-off between IoT devices' security needs and delays in communication caused by the selection of the AES algorithm operation mode.

Abstract
Lung cancer is the deadliest type of cancer worldwide and late detection is the major factor for the low survival rate of patients. Low dose computed tomography has been suggested as a potential screening tool but manual screening is costly and time-consuming. This has fuelled the development of automatic methods for the detection, segmentation and characterisation of pulmonary nodules. In spite of promising results, the application of automatic methods to clinical routine is not straightforward and only a limited number of studies have addressed the problem in a holistic way. With the goal of advancing the state of the art, the Lung Nodule Database (LNDb) Challenge on automatic lung cancer patient management was organized. The LNDb Challenge addressed lung nodule detection, segmentation and characterization as well as prediction of patient follow-up according to the 2017 Fleischner society pulmonary nodule guidelines. 294 CT scans were thus collected retrospectively at the Centro Hospitalar e Universitrio de So Joo in Porto, Portugal and each CT was annotated by at least one radiologist. Annotations comprised nodule centroids, segmentations and subjective characterization. 58 CTs and the corresponding annotations were withheld as a separate test set. A total of 947 users registered for the challenge and 11 successful submissions for at least one of the sub-challenges were received. For patient follow-up prediction, a maximum quadratic weighted Cohen's kappa of 0.580 was obtained. In terms of nodule detection, a sensitivity below 0.4 (and 0.7) at 1 false positive per scan was obtained for nodules identified by at least one (and two) radiologist(s). For nodule segmentation, a maximum Jaccard score of 0.567 was obtained, surpassing the interobserver variability. In terms of nodule texture characterization, a maximum quadratic weighted Cohen's kappa of 0.733 was obtained, with part solid nodules being particularly challenging to classify correctly. Detailed analysis of the proposed methods and the differences in performance allow to identify the major challenges remaining and future directions data collection, augmentation/generation and evaluation of under-represented classes, the incorporation of scan-level information for better decision making and the development of tools and challenges with clinical-oriented goals. The LNDb Challenge and associated data remain publicly available so that future methods can be tested and benchmarked, promoting the development of new algorithms in lung cancer medical image analysis and patient followup recommendation.

Abstract
Current state-of-the-art medical image segmentation methods require high quality datasets to obtain good performance. However, medical specialists often disagree on diagnosis, hence, datasets contain contradictory annotations. This, in turn, leads to difficulties in the optimization process of Deep Learning models and hinder performance. We propose a method to estimate uncertainty in Convolutional Neural Network (CNN) segmentation models, that makes the training of CNNs more robust to contradictory annotations. In this work, we model two types of uncertainty, heteroscedastic and epistemic, without adding any additional supervisory signal other than the ground-truth segmentation mask. As expected, the uncertainty is higher closer to vessel boundaries, and on top of thinner and less visible vessels where it is more likely for medical specialists to disagree. Therefore, our method is more suitable to learn from datasets created with heterogeneous annotators. We show that there is a correlation between the uncertainty estimated by our method and the disagreement in the segmentation provided by two different medical specialists. Furthermore, by explicitly modeling the uncertainty, the Intersection over Union of the segmentation network improves 5.7 percentage points.

Abstract
Vulnerability scanning tools can help secure the computer networks of organisations. Triggered by the release of the Tsunami vulnerability scanner by Google, the authors analysed and compared the commonly used, free-to-use vulnerability scanners. The performance, accuracy and precision of these scanners are quite disparate and vary accordingly to the target systems. The computational, memory and network resources required be these scanners also differ. We present a recent and detailed comparison of such tools that are available for use by organisations with lower resources such as small and medium-sized enterprises.