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Publicações

Publicações por Alexandre Henrique Neto

2023

Gastric cancer detection based on Colorectal Cancer transfer learning

Autores
Nobrega, S; Neto, A; Coimbra, M; Cunha, A;

Publicação
2023 IEEE 7TH PORTUGUESE MEETING ON BIOENGINEERING, ENBENG

Abstract
Gastric Cancer (GC) and Colorectal Cancer (CRC) are some of the most common cancers in the world. The most common diagnostic methods are upper endoscopy and biopsy. Possible expert distractions can lead to late diagnosis. GC is a less studied malignancy than CRC, leading to scarce public data that difficult the use of AI detection methods, unlike CRC where public data are available. Considering that CRC endoscopic images present some similarities with GC, a CRC Transfer Learning approach could be used to improve AI GC detectors. This paper evaluates a novel Transfer Learning approach for real-time GC detection, using a YOLOv4 model pre-trained on CRC detection. The results achieved are promising since GC detection improved relatively to the traditional Transfer Learning strategy.

2022

Preliminary Study of Deep Learning Algorithms for Metaplasia Detection in Upper Gastrointestinal Endoscopy

Autores
Neto, A; Ferreira, S; Libânio, D; Ribeiro, MD; Coimbra, MT; Cunha, A;

Publicação
Wireless Mobile Communication and Healthcare - 11th EAI International Conference, MobiHealth 2022, Virtual Event, November 30 - December 2, 2022, Proceedings

Abstract
Precancerous conditions such as intestinal metaplasia (IM) have a key role in gastric cancer development and can be detected during endoscopy. During upper gastrointestinal endoscopy (UGIE), misdiagnosis can occur due to technical and human factors or by the nature of the lesions, leading to a wrong diagnosis which can result in no surveillance/treatment and impairing the prevention of gastric cancer. Deep learning systems show great potential in detecting precancerous gastric conditions and lesions by using endoscopic images and thus improving and aiding physicians in this task, resulting in higher detection rates and fewer operation errors. This study aims to develop deep learning algorithms capable of detecting IM in UGIE images with a focus on model explainability and interpretability. In this work, white light and narrow-band imaging UGIE images collected in the Portuguese Institute of Oncology of Porto were used to train deep learning models for IM classification. Standard models such as ResNet50, VGG16 and InceptionV3 were compared to more recent algorithms that rely on attention mechanisms, namely the Vision Transformer (ViT), trained in 818 UGIE images (409 normal and 409 IM). All the models were trained using a 5-fold cross-validation technique and for validation, an external dataset will be tested with 100 UGIE images (50 normal and 50 IM). In the end, explainability methods (Grad-CAM and attention rollout) were used for more clear and more interpretable results. The model which performed better was ResNet50 with a sensitivity of 0.75 (±0.05), an accuracy of 0.79 (±0.01), and a specificity of 0.82 (±0.04). This model obtained an AUC of 0.83 (±0.01), where the standard deviation was 0.01, which means that all iterations of the 5-fold cross-validation have a more significant agreement in classifying the samples than the other models. The ViT model showed promising performance, reaching similar results compared to the remaining models. © 2023, ICST Institute for Computer Sciences, Social Informatics and Telecommunications Engineering.

2023

Colonoscopic Polyp Detection with Deep Learning Assist

Autores
Neto, A; Couto, D; Coimbra, MT; Cunha, A;

Publicação
Proceedings of the 18th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications, VISIGRAPP 2023, Volume 4: VISAPP, Lisbon, Portugal, February 19-21, 2023.

Abstract
Colorectal cancer is the third most common cancer and the second cause of cancer-related deaths in the world. Colonoscopic surveillance is extremely important to find cancer precursors such as adenomas or serrated polyps. Identifying small or flat polyps can be challenging during colonoscopy and highly dependent on the colonoscopist's skills. Deep learning algorithms can enable improvement of polyp detection rate and consequently assist to reduce physician subjectiveness and operation errors. This study aims to compare YOLO object detection architecture with self-attention models. In this study, the Kvasir-SEG polyp dataset, composed of 1000 colonoscopy annotated still images, were used to train (700 images) and validate (300images) the performance of polyp detection algorithms. Well-defined architectures such as YOLOv4 and different YOLOv5 models were compared with more recent algorithms that rely on self-attention mechanisms, namely the DETR model, to understand which technique can be more helpful and reliable in clinical practice. In the end, the YOLOv5 proved to be the model achieving better results for polyp detection with 0.81 mAP, however, the DETR had 0.80 mAP proving to have the potential of reaching similar performances when compared to more well-established architectures. © 2023 by SCITEPRESS - Science and Technology Publications, Lda.

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