Abstract
Many text classification problems in social networks, and other contexts, are also dynamic problems, where concepts drift through time, and meaningful labels are dynamic. In Twitter-based applications in particular, ensembles are often applied to problems that fit this description, for example sentiment analysis or adapting to drifting circumstances. While it can be straightforward to request different classifiers' input on such ensembles, our goal is to boost dynamic ensembles by combining performance metrics as efficiently as possible. We present a twofold performance-based framework to classify incoming tweets based on recent tweets. On the one hand, individual ensemble classifiers' performance is paramount in defining their contribution to the ensemble. On the other hand, examples are actively selected based on their ability to effectively contribute to the performance in classifying drifting concepts. The main step of the algorithm uses different performance metrics to determine both each classifier strength in the ensemble and each example importance, and hence lifetime, in the learning process. We demonstrate, on a drifted benchmark dataset, that our framework drives the classification performance considerably up for it to make a difference in a variety of applications.

Abstract
Network security encompasses distinct technologies and protocols, being behaviour based network Intrusion Detection Systems (IDS) a promising application to detect and identify zero-day attacks and vulnerabilities exploits. In order to overcome the weaknesses of signature-based IDS, behaviour-based IDS applies a wide set of machine learning technologies to learn the normal behaviour of the network, making it possible to detect malicious and not yet seen activities. The machine learning techniques that can be applied to IDS are vast, as are the methods to generate the datasets used for testing. This paper aims to evaluate CSE-CIC-IDS2018 dataset and benchmark a set of supervised bioinspired machine learning algorithms, namely CLONALG Artificial Immune System, Learning Vector Quantization (LVQ) and Back-Propagation Multi-Layer Perceptron (MLP). The results obtained were also compared with an ensemble strategy based on a majority voting algorithm. The results obtained show the appropriateness of using the dataset to test behaviour based network intrusion detection algorithms and the efficiency of MLP algorithm to detect zero-day attacks, when comparing with CLONALG and LVQ. © 2021, Springer Nature Singapore Pte Ltd.

Abstract

Abstract
A main problem for predicting cell line interactions with chemical compounds is the lack of a computational representation for cell lines. We describe a method for characterizing cell lines from scientific literature. We retrieve and process cell line-related scientific papers, perform a document classification algorithm, and then obtain a description of the information space of each cell line. We have successfully characterized a set of 300+ cell lines. © 2020 Owner/Author.

Abstract
Background: The clinical decision-making process in pressure ulcer management is complex, and its quality depends on both the nurse's experience and the availability of scientific knowledge. This process should follow evidence-based practices incorporating health information technologies to assist health care professionals, such as the use of clinical decision support systems. These systems, in addition to increasing the quality of care provided, can reduce errors and costs in health care. However, the widespread use of clinical decision support systems still has limited evidence, indicating the need to identify and evaluate its effects on nursing clinical practice. Objective: The goal of the review was to identify the effects of nurses using clinical decision support systems on clinical decision making for pressure ulcer management. Methods: The systematic review was conducted in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) recommendations. The search was conducted in April 2019 on 5 electronic databases: MEDLINE, SCOPUS, Web of Science, Cochrane, and CINAHL, without publication date or study design restrictions. Articles that addressed the use of computerized clinical decision support systems in pressure ulcer care applied in clinical practice were included. The reference lists of eligible articles were searched manually. The Mixed Methods Appraisal Tool was used to assess the methodological quality of the studies. Results: The search strategy resulted in 998 articles, 16 of which were included. The year of publication ranged from 1995 to 2017, with 45% of studies conducted in the United States. Most addressed the use of clinical decision support systems by nurses in pressure ulcers prevention in inpatient units. All studies described knowledge-based systems that assessed the effects on clinical decision making, clinical effects secondary to clinical decision support system use, or factors that influenced the use or intention to use clinical decision support systems by health professionals and the success of their implementation in nursing practice. Conclusions: The evidence in the available literature about the effects of clinical decision support systems (used by nurses) on decision making for pressure ulcer prevention and treatment is still insufficient. No significant effects were found on nurses' knowledge following the integration of clinical decision support systems into the workflow, with assessments made for a brief period of up to 6 months. Clinical effects, such as outcomes in the incidence and prevalence of pressure ulcers, remain limited in the studies, and most found clinically but nonstatistically significant results in decreasing pressure ulcers. It is necessary to carry out studies that prioritize better adoption and interaction of nurses with clinical decision support systems, as well as studies with a representative sample of health care professionals, randomized study designs, and application of assessment instruments appropriate to the professional and institutional profile. In addition, long-term follow-up is necessary to assess the effects of clinical decision support systems that can demonstrate a more real, measurable, and significant effect on clinical decision making.

Abstract
Quantum annealing provides a method to solve combinatorial optimization problems in complex energy landscapes by exploiting thermal fluctuations that exist in a physical system. This work introduces the mapping of a graph coloring problem based on pseudo-Boolean constraints to a working graph of the D-Wave Systems Inc. We start from the problem formulated as a set of constraints represented in propositional logic. We use the SATyrus approach to transform this set of constraints to an energy minimization problem. We convert the formulation to a quadratic unconstrained binary optimization problem (QUBO), applying polynomial reduction when needed, and solve the problem using different approaches: (a) classical QUBO using simulated annealing in a von Neumann machine; (b) QUBO in a simulated quantum environment; (c) actual quantum 1, QUBO using the D-Wave quantum machine and reducing polynomial degree using a D-Wave library; and (d) actual quantum 2, QUBO using the D-Wave quantum machine and reducing polynomial degree using our own implementation. We study how the implementations using these approaches vary in terms of the impact on the number of solutions found (a) when varying the penalties associated with the constraints and (b) when varying the annealing approach, simulated (SA) versus quantum (QA). Results show that both SA and QA produce good heuristics for this specific problem, although we found more solutions through the QA approach.